The Anseth group designs biomaterial scaffolds with highly-controlled architectures and chemistries for three-dimensional cell culture, tissue regeneration, and biological assays. We are particularly interested in understanding how cells receive information from their microenvironment and then use this information to design functional biomaterials. Our approach exploits classical engineering principles and modeling, as control is required on many time scales, from seconds to months, and on many size scales, from the molecular to macroscopic. Our research spans the spectrum of fundamental studies to better understand the role of the biomaterial environment on cell function and the biology of tissue formation to targeted clinical applications in the design of in situ forming cell carriers that promote healing.
Biomaterials, regenerative medicine, stem cells and polymer chemistry
CHEN 4805 - Biomaterials
Provides an overview of biomaterials. Covers major classes of materials used in medical applications, properties, degradation mechanisms, and characterization methods, foreign body response, methods to control physiological response to biomaterial surfaces, biocompatibility, biomaterials used in soft and hard tissue replacements, drug delivery devices and tissue engineering, and design criteria for developing a material for a given biological application. Recommended prerequisite: CHEM 3331.