The Tetrahymena ribozyme cleaves a 5 '-methylene phosphonate monoester similar to 10(2)-fold faster than a normal phosphate diester: Implications for enzyme catalysis of phosphoryl transfer reactions
Journal Article
Overview
publication date
- September 18, 2001
has subject area
- Animals
- Biochemical Phenomena - Kinetics
- Catalysis
- Diagnostic Uses of Chemicals - Molecular Probes
- Enzymes - RNA, Catalytic
- Esters
- Laboratory Chemicals - Molecular Probes
- Mechanical Phenomena - Kinetics
- Models, Chemical
- Oligonucleotides
- Organophosphonates
- RNA, Untranslated - RNA, Catalytic
- Substrate Specificity
- Tetrahymena thermophila
- Thermodynamics
Full Author List
- Liao XM; Anjaneyulu PSR; Curley JF; Hsu M; Boehringer M; Caruthers MH; Piccirilli JA
published in
- Biochemistry Journal
Other Profiles
Digital Object Identifier (DOI)
Additional Document Info
start page
- 10911
end page
- 10926
volume
- 40
issue
- 37