Biochemistry Journal

Overview

publication venue for

• The RNA-Binding Domain of hnRNP U Extends beyond the RGG/RG Motifs 2024
• Structure and Function of ArnD. A Deformylase Essential for Lipid A Modification with 4-Amino-4-deoxy-l-arabinose and Polymyxin Resistance 2023
• Slow Dissociation from the PARP1-HPF1 Complex Drives Inhibitor Potency 2023
• Targeting the Conformational Change in ArnA Dehydrogenase for Selective Inhibition of Polymyxin Resistance 2023
• A Closed Form Model for Molecular Ratchet-Type Chemically Induced Dimerization Modules 2023
• How to Recruit a Promiscuous Enzyme to Serve a New Function 2023
• An Extended DNA Binding Domain of the Estrogen Receptor Alpha Directly Interacts with RNAs in Vitro 2022
• Replication Protein A Utilizes Differential Engagement of Its DNA- Binding Domains to Bind Biologically Relevant ssDNAs in Diverse Binding Modes 2022
• The DNA-Binding High-Mobility Group Box Domain of Sox Family Proteins Directly Interacts with RNA In Vitro 2022
• Optogenetic Analysis of Allosteric Control in Protein Tyrosine Phosphatases 2021
• Rosetta-Enabled Structural Prediction of Permissive Loop Insertion Sites in Proteins 2020
• Engineering of a Brighter Variant of the FusionRed Fluorescent Protein Using Lifetime Flow Cytometry and Structure-Guided Mutations 2020
• Activation Loop Dynamics Are Coupled to Core Motions in Extracellular Signal-Regulated Kinase-2 2020
• Feline Interleukin-31 Shares Overlapping Epitopes with the Oncostatin M Receptor and IL-31RA 2020
• Probing the Conformational Changes Associated with DNA Binding to PARP1 2020
• Nonspecific Binding of RNA to PARP1 and PARP2 Does Not Lead to Catalytic Activation 2019
• Correction to "Abietane-Type Diterpenoids Inhibit Protein Tyrosine Phosphatases by Stabilizing an Inactive Enzyme Conformation". 2019
• Recent Structural Insights into Polycomb Repressive Complex 2 Regulation and Substrate Binding 2019
• Evolutionarily Conserved Allosteric Communication in Protein Tyrosine Phosphatases 2018
• Abietane-Type Diterpenoids Inhibit Protein Tyrosine Phosphatases by Stabilizing an Inactive Enzyme Conformation 2018
• Abietane-Type Diterpenoids Inhibit Protein Tyrosine Phosphatases by Stabilizing an Inactive Enzyme Conformation. 2018
• Sedimentation Velocity Analysis with Fluorescence Detection of Mutant Huntingtin Exon 1 Aggregation in Drosophila melanogaster and Caenorhabditis elegans 2017
• Human CST Prefers G-Rich but Not Necessarily Telomeric Sequences 2017
• Extreme Dynamics in the BamA β-Barrel Seam 2017
• Protein Displacement by Herpes Helicase-Primase and the Key Role of UL42 during Helicase-Coupled DNA Synthesis by the Herpes Polymerase 2017
• Multimodal Recognition of Diverse Peptides by the C-Terminal SH2 Domain of Phospholipase C-γ1 Protein 2017
• Fine Epitope Mapping of Two Antibodies Neutralizing the Bordetella Adenylate Cyclase Toxin 2017
• Regulation of a Coupled MARCKS-PI3K Lipid Kinase Circuit by Calmodulin: Single-Molecule Analysis of a Membrane-Bound Signaling Module 2016
• Interfering with the Dimerization of the ErbB Receptors by Transmembrane Domain-Derived Peptides Inhibits Tumorigenic Growth in Vitro and in Vivo 2016
• Tying up the Ends: Plasticity in the Recognition of Single-Stranded DNA at Telomeres 2016
• Effects of Acyclovir, Foscarnet, and Ribonucleotides on Herpes Simplex Virus-1 DNA Polymerase: Mechanistic Insights and a Novel Mechanism for Preventing Stable Incorporation of Ribonucleotides into DNA 2016
• Structure-Based Assignment of Ile, Leu, and Val Methyl Groups in the Active and Inactive Forms of the Mitogen-Activated Protein Kinase Extracellular Signal-Regulated Kinase 2015
• Polymerase and Exonuclease Activities in Herpes Simplex Virus Type 1 DNA Polymerase Are Not Highly Coordinated 2015
• Slow Inhibition and Conformation Selective Properties of Extracellular Signal-Regulated Kinase 1 and 2 Inhibitors 2015
• A Radical Intermediate in the Conversion of Pentachlorophenol to Tetrachlorohydroquinone by Sphingobium chlorophenolicum 2014
• Increasing and Decreasing the Ultrastability of Bacterial Chemotaxis Core Signaling Complexes by Modifying Protein-Protein Contacts 2014
• The interface between Escherichia coli elongation factor Tu and aminoacyl-tRNA. 2014
• The Structure and Specificity of the Type III Secretion System Effector NleC Suggest a DNA Mimicry Mechanism of Substrate Recognition 2014
• Partial Unfolding of a Monoclonal Antibody: Role of a Single Domain in Driving Protein Aggregation 2014
• New Insights into Bacterial Chemoreceptor Array Structure and Assembly from Electron Cryotomography 2014
• Single-Molecule Studies Reveal a Hidden Key Step in the Activation Mechanism of Membrane-Bound Protein Kinase C-α 2014
• Structural Basis for Substrate Specificity in ArnB. A Key Enzyme in the Polymyxin Resistance Pathway of Gram-Negative Bacteria 2014
• Structure, Function, and On-Off Switching of a Core Unit Contact between CheA Kinase and CheW Adaptor Protein in the Bacterial Chemosensory Array: A Disulfide Mapping and Mutagenesis Study 2013
• Structure of Mediator of RhoA-Dependent Invasion (MRDI) Explains Its Dual Function as a Metabolic Enzyme and a Mediator of Cell Invasion 2013
• The PH Domain of Phosphoinositide-Dependent Kinase-1 Exhibits a Novel, Phospho-Regulated Monomer-Dimer Equilibrium with Important Implications for Kinase Domain Activation: Single-Molecule and Ensemble Studies 2013
• Defining a Key Receptor-CheA Kinase Contact and Elucidating Its Function in the Membrane-Bound Bacterial Chemosensory Array: A Disulfide Mapping and TAM-IDS Study 2013
• The 3.2 Å Resolution Structure of a Receptor:CheA:CheW Signaling Complex Defines Overlapping Binding Sites and Key Residue Interactions within Bacterial Chemosensory Arrays 2013
• The Orphan Protein Bis-γ-glutamylcystine Reductase Joins the Pyridine Nucleotide Disulfide Reductase Family 2013
• Synthetic Analogues of Nickel Superoxide Dismutase: A New Role for Nickel in Biology 2013
• Isolated Bacterial Chemosensory Array Possesses Quasi- and Ultrastable Components: Functional Links between Array Stability, Cooperativity, and Order 2012
• Duplex destabilization by four ribosomal DEAD-box proteins. 2012
• Single-Molecule Studies of the Lysine Riboswitch Reveal Effector-Dependent Conformational Dynamics of the Aptamer Domain 2012
• A Small Molecule Inhibitor of Pot1 Binding to Article Telomeric DNA 2012
• Hydrophobic Contributions to the Membrane Docking of Synaptotagmin 7 C2A Domain: Mechanistic Contrast between Isoforms 1 and 7 2012
• Single-Molecule Fluorescence Resonance Energy Transfer Shows Uniformity in TATA Binding Protein-Induced DNA Bending and Heterogeneity in Bending Kinetics 2012
• Pentachlorophenol Hydroxylase, a Poorly Functioning Enzyme Required for Degradation of Pentachlorophenol by Sphingobium chlorophenolicum 2012
• Assembly of Membrane-Bound Protein Complexes: Detection and Analysis by Single Molecule Diffusion 2012
• Initial- and Processive-Cut Products Reveal Cellobiohydrolase Rate Limitations and the Role of Companion Enzymes 2012
• The GRP1 PH Domain, Like the AKT1 PH Domain, Possesses a Sentry Glutamate Residue Essential for Specific Targeting to Plasma Membrane PI(3,4,5)P₃ 2011
• Comparative Hydrogen-Deuterium Exchange for a Mesophilic vs Thermophilic Dihydrofolate Reductase at 25 degrees C: Identification of a Single Active Site Region with Enhanced Flexibility in the Mesophilic Protein 2011
• Schizosaccharomyces pombe Protection of Telomeres 1 Utilizes Alternate Binding Modes To Accommodate Different Telomeric Sequences 2011
• B Family DNA Polymerases Asymmetrically Recognize Pyrimidines and Purines 2011
• Sequence-Specific Binding to Telomeric DNA Is Not a Conserved Property of the Cdc13 DNA Binding Domain 2011
• OS-FRET: A New One-Sample Method for Improved FRET Measurements 2011
• Regulation of Influenza RNA Polymerase Activity and the Switch between Replication and Transcription by the Concentrations of the vRNA 5′ End, the Cap Source, and the Polymerase 2010
• Multiple Turnovers of the Nicotino-Enzyme PdxB Require α-Keto Acids as Cosubstrates 2010
• Enhanced product stability in the hammerhead ribozyme. 2010
• Ultrafast Dynamics Show That the Theophylline and 3-Methylxanthine Aptamers Employ a Conformational Capture Mechanism for Binding Their Ligands 2010
• Parallel Multiplicative Target Screening against Divergent Bacterial Replicases: Identification of Specific Inhibitors with Broad Spectrum Potential 2010
• Mechanisms by Which Human DNA Primase Chooses To Polymerize a Nucleoside Triphosphate 2010
• Physical Instability of a Therapeutic Fc Fusion Protein: Domain Contributions to Conformational and Colloidal Stability 2009
• Herpes Simplex Virus-1 DNA Primase: A Remarkably Inaccurate yet Selective Polymerase 2009
• Herpes Simplex Virus-1 Helicase-Primase: Roles of Each Subunit in DNA Binding and Phosphodiester Bond Formation 2009
• Engineered Socket Study of Signaling through a Four-Helix Bundle: Evidence for a Yin-Yang Mechanism in the Kinase Control Module of the Aspartate Receptor 2009
• Interaction of Human DNA Polymerase alpha and DNA Polymerase I from Bacillus stearothermophilus with Hypoxanthine and 8-Oxoguanine Nucleotides 2009
• Ambivalent Incorporation of the Fluorescent Cytosine Analogues tC and tCo by Human DNA Polymerase α and Klenow Fragment 2009
• Nonadditivity in the Recognition of Single-Stranded DNA by the Schizosaccharomyces pombe Protection of Telomeres 1 DNA-Binding Domain, Pot1-DBD 2009
• The Core Signaling Proteins of Bacterial Chemotaxis Assemble To Form an Ultrastable Complex 2009
• Discrimination between Right and Wrong Purine dNTPs by DNA Polymerase I from Bacillus stearothermophilus 2009
• Thermal Domain Motions of CheA Kinase in Solution: Disulfide Trapping Reveals the Motional Constraints Leading to Trans-autophosphorylation 2009
• Identifying the Features of Purine dNTPs that Allow Accurate and Efficient DNA Replication by Herpes Simplex Virus I DNA Polymerase 2009
• Redox Regulation of SH2-Domain-Containing Protein Tyrosine Phosphatases by Two Backdoor Cysteines 2009
• Role of the 2-Amino Group of Purines during dNTP Polymerization by Human DNA Polymerase alpha 2009
• Differential RNA-dependent ATPase activities of four rRNA processing yeast DEAD-box proteins. 2008
• Molecular Mechanism of an Oncogenic Mutation That Alters Membrane Targeting: Glu17Lys Modifies the PIP Lipid Specificity of the AKT1 PH Domain 2008
• Interaction of herpes primase with the sugar of a NTP 2008
• Effect of PIP₂ binding on the membrane docking geometry of PKCα C2 domain:: An EPR site-directed spin-labeling and relaxation study 2008
• Catalytic diversity of extended hammerhead ribozymes. 2008
• Deciphering the mechanism of thermodynamic accommodation of telomeric oligonucleotide sequences by the Schizosaccharomyces pombe protection of telomeres 1 (Pot1pN) protein 2008
• A Trade-Off between Catalytic Power and Substrate Inhibition in TCHQ Dehalogenase 2008
• X-ray structure and microtubule interaction of the motor domain of neurospora crassa NcKin3, a kinesin with unusual processivity 2008
• Mass instability in isolated recombinant FixL heme domains of Bradyrhizobium japonicum 2008
• Structure of the conserved HAMP domain in an intact, membrane-bound chemoreceptor: A disulfide mapping study 2007
• Mutational analysis of the purine riboswitch aptamer domain 2007
• Why metabolic enzymes are essential or nonessential for growth of Escherichia coli k12 on glucose 2007
• Pre-Steady-State Kinetic Studies of the Reductive Dehalogenation Catalyzed by Tetrachlorohydroquinone Dehalogenase 2007
• Exploring the specificity of bacterial elongation factor Tu for different tRNAs. 2007
• Oxidation of methionine residues in recombinant human interleukin-1 receptor antagonist: Implications of conformational stability on protein oxidation kinetics 2007
• Mechanism of specific membrane targeting by C2 domains:: Localized pools of target lipids enhance Ca²⁺ affinity 2007
• Mechanism of the Severe Inhibition of Tetrachlorohydroquinone Dehalogenase by Its Aromatic Substrates 2007
• Efficient ligation of the Schistosoma hammerhead ribozyme 2007
• Human DNA polymerase alpha uses a combination of positive and negative selectivity to polymerize purine dNTPs with high fidelity 2007
• CheA kinase of bacterial chemotaxis: Chemical mapping of four essential docking sites 2006
• Temperature dependence of benzyl alcohol- and 8-anilinonaphthalene-1-sulfonate-induced aggregation of recombinant human interleukin-1 receptor antagonist 2006
• Metal ion dependence, thermodynamics, and kinetics for intramolecular docking of a GAAA tetraloop and receptor connected by a flexible linker 2006
• Identification of the determinants for the specific recognition of single-strand telomeric DNA by Cdc13 2006
• Herpes simplex virus 1 primase employs Watson-Crick hydrogen bonding to identify cognate nucleoside triphosphates 2005
• Herpes simplex virus 1 primase employs watson-crick hydrogen bonding to identify cognate nucleoside triphosphates. 2005
• Hammerheads derived from sTRSV show enhanced cleavage and ligation rate constants. 2005
• Ubiquitination of p21^Cip1/WAF1 by SCF^Skp2:: Substrate requirement and ubiquitination site selection 2005
• Evidence that the adaptation region of the aspartate receptor is a dynamic four-helix bundle: Cysteine and disulfide scanning studies 2005
• Predicting the binding affinities of misacylated tRNAs for Thermus thermophilus EF-Tu.GTP. 2005
• A Mechanistic Investigation of the Thiol−Disulfide Exchange Step in the Reductive Dehalogenation Catalyzed by Tetrachlorohydroquinone Dehalogenase 2005
• Conserved glycine residues in the cytoplasmic domain of the aspartate receptor play essential roles in kinase coupling and on-off switching 2005
• Escherichia coli DbpA is a 3' --> 5' RNA helicase. 2005
• Comparison of the global structure and dynamics of native and unmodified tRNA 2005
• Crystal structure and mechanism of the Escherichia coli ArnA (PmrI) transformylase domain. An enzyme for lipid A modification with 4-amino-4-deoxy-L-arabinose and polymyxin resistance. 2005
• Adaptation mechanism of the aspartate receptor: Electrostatics of the adaptation subdomain play a key role in modulating kinase activity 2005
• Call activation of the cPLA(2) C2 domain: Ordered binding of two Ca2+ ions with positive cooperativity 2004
• GRP1 pleckstrin homology domain: Activation parameters and novel search mechanism for rare target lipid 2004
• Evidence for increased local flexibility in psychrophilic alcohol dehydrogenase relative to its thermophilic homologue 2004
• Divergence of Function in the Thioredoxin Fold Suprafamily:  Evidence for Evolution of Peroxiredoxins from a Thioredoxin-like Ancestor 2004
• Crystal structure of Escherichia coli ArnA (PmrI) decarboxylase domain.: A key enzyme for lipid a modification with 4-amino-4-deoxy-L-arabinose and polymyxin resistance 2004
• Human DNA primase uses Watson-Crick hydrogen bonds to distinguish between correct and incorrect nucleoside triphosphates 2004
• Herpes simplex virus-1 primase: A polymerase with extraordinarily low fidelity 2004
• Herpes simplex virus-1 primase: a polymerase with extraordinarily low fidelity. 2004
• Contribution of the esterified amino acid to the binding of aminoacylated tRNAs to the ribosomal P- and A-sites. 2004
• The affinity of elongation factor Tu for an aminoacyl-tRNA is modulated by the esterified amino acid. 2004
• Microtubule-kinesin interface mutants reveal a site critical for communication 2004
• Side chains at the membrane-water interface modulate the signaling state of a transmembrane receptor 2004
• Mechanism of primer synthesis by the herpes simplex virus 1 helicase-primase 2004
• Histone -: DNA binding free energy cannot be measured in dilution-driven dissociation experiments 2004
• Membrane-docking loops of the cPLA2 C2 domain: Detailed structural analysis of the protein-membrane interface via site-directed spin-labeling 2003
• Membrane-docking loops of the cPLA2 C2 domain: detailed structural analysis of the protein-membrane interface via site-directed spin-labeling. 2003
• Facile polymerization of dNTPs bearing unnatural base analogues by DNA polymerase alpha and Klenow fragment (DNA polymerase I) 2003
• Facile polymerization of dNTPs bearing unnatural base analogues by DNA polymerase alpha and Klenow fragment (DNA polymerase I). 2003
• Sequence-specific and 3 '-end selective single-strand DNA binding by the Oxytricha nova telomere end binding protein alpha subunit 2003
• High-pressure refolding of bikunin protein aggregates: efficacy and thermodynamics. 2003
• Pressure-induced aggregation of interleukin-1 receptor antagonist (IL-1ra): mechanism and thermodynamics 2003
• Stability of benzotriazole derivatives with free Cu, Zn, Co, and metal-containing enzymes: Binding and interaction with superoxide dismutase and vitamin B-12. 2003
• The Euplotes La motif protein p43 has properties of a telomerase-specific subunit 2003
• Site-directed mutagenesis reveals the thermodynamic requirements for single-stranded DNA recognition by the telomere-binding protein Cdc13 2003
• Mapping out regions on the surface of the aspartate receptor that are essential for kinase activation 2003
• Motor domain mutation traps kinesin as a microtubule rigor complex 2003
• Role of a heterogeneous free state in the formation of a specific RNA-theophylline complex 2003
• C2 domain of protein kinase Cα:: Elucidation of the membrane docking surface by site-directed fluorescence and spin labeling 2003
• Oxidative dimer formation is the critical rate-limiting step for Parkinson's disease α-synuclein fibrillogenesis 2003
• Cooperative binding of single-stranded telomeric DNA by the Pot1 protein of Schizosaccharomyces pombe 2002
• Key role of template sequence for primer synthesis by the herpes simplex virus 1 helicase-primase 2002
• Synthesis of nucleotide analogues that potently and selectively inhibit human DNA primase 2002
• Structural and energetic analysis of metal ions essential to SRP signal recognition domain assembly 2002
• The global conformation of the hammerhead ribozyme determined using residual dipolar couplings 2002
• C2 domains of protein kinase C isoforms α, β, and γ:: Activation parameters and calcium stoichiometries of the membrane-bound state 2002
• Internal equilibrium of the hammerhead ribozyme is altered by the length of certain covalent cross-links 2002
• Aggregation of granulocyte colony stimulating factor under physiological conditions: Characterization and thermodynamic inhibition 2002
• Membrane orientation and position of the C2 domain from cPLA2 by site-directed spin labeling 2002
• Spectroscopic Characterization and O₂ Reactivity of the Trinuclear Cu Cluster of Mutants of the Multicopper Oxidase Fet3p 2002
• The p58 subunit of human DNA primase is important for primer initiation, elongation, and counting 2002
• Cooperative binding of ATP and RNA substrates to the DEAD/H protein DbpA 2002
• Cation charge and size selectivity of the C2 domain of cytosolic phospholipase A(2) 2002
• Effects of nucleotide analogues on Euplotes aediculatus telomerase processivity: Evidence for product-assisted translocation 2002
• Characterization of the Initial Steps in the Reductive Dehalogenation Catalyzed by Tetrachlorohydroquinone Dehalogenase 2002
• The Reaction Catalyzed by Tetrachlorohydroquinone Dehalogenase Does Not Involve Nucleophilic Aromatic Substitution 2002
• Inhibition of CMP-sialic acid transport into Golgi vesicles by nucleoside monophosphates 2001
• Energetics and affinity of the histone octamer for defined DNA sequences 2001
• The Tetrahymena ribozyme cleaves a 5′-methylene phosphonate monoester ∼10²-fold faster than a normal phosphate diester:: Implications for enzyme catalysis of phosphoryl transfer reactions 2001
• Changes in protein conformational mobility upon activation of ERK2 as detected by hydrogen exchange. 2001
• A stem-loop of Tetrahymena telomerase RNA distant from the template potentiates RNA folding and telomerase activity 2001
• C2 domains from different Ca²⁺ signaling pathways display functional and mechanistic diversity 2001
• Probing of metal-binding domains of RNA hairpin loops by laser-induced lanthanide(III) luminescence 2001
• Multiple folding pathways for the P4-P6 RNA domain 2000
• Active site dynamics in the lead-dependent ribozyme 2000
• Attractant regulation of the aspartate receptor-kinase complex: Limited cooperative interactions between receptors and effects of the receptor modification state 2000
• Mapping contacts between Escherichia coli alanyl tRNA synthetase and 2 ' hydroxyls using a complete tRNA molecule 2000
• Catalytic reaction pathway for the mitogen-activated protein kinase ERK2 2000
• Recruitment of a Double Bond Isomerase To Serve as a Reductive Dehalogenase during Biodegradation of Pentachlorophenol 2000
• Hammerhead cleavage of the phosphorodithioate linkage 2000
• Role of the loop containing residue 115 in the induced-fit mechanism of the bacterial cell wall biosynthetic enzyme MurA 2000
• Intact aminoacyl-tRNA is required to trigger GTP hydrolysis by elongation factor Tu on the ribosome 2000
• Using phosphorothioate-substituted RNA to investigate the thermodynamic role of phosphates in a sequence specific RNA-protein complex 2000
• Catalytic reaction pathway for the mitogen-activated protein kinase ERK2 2000
• RNA tertiary folding monitored by fluorescence of covalently attached pyrene 1999
• Abasic template lesions are strong chain terminators for DNA primase but not for DNA polymerase alpha during the synthesis of new DNA strands 1999
• Interactions of DNA with human DNA primase monitored with photoactivatable cross-linking agents: Implications for the role of the p58 subunit 1999
• Human DNA primase: Anion inhibition, manganese stimulation, and their effects on in vitro start-site selection 1999
• Signaling domain of the aspartate receptor is a helical hairpin with a localized kinase docking surface: Cysteine and disulfide scanning studies 1999
• Energetics and cooperativity of tertiary hydrogen bonds in RNA structure 1999
• Arg304 of human DNA primase is a key contributor to catalysis and NTP binding: Primase and the family X polymerases share significant sequence homology 1999
• Evidence that pcpA encodes 2,6-dichlorohydroquinone dioxygenase, the ring cleavage enzyme required for pentachlorophenol degradation in Sphingomonas chlorophenolica strain ATCC 39723 1999
• Identification of a site critical for kinase regulation on the central processing unit (CPU) helix of the aspartate receptor 1999
• Location of the membrane-docking face on the Ca2+-activated C2 domain of cytosolic phospholipase A(2) 1998
• Kinetic analysis of the RNA-dependent adenosinetriphosphatase activity of DbpA, an Escherichia coli DEAD protein specific for 23S ribosomal RNA 1998
• Thermodynamic dissection of the substrate-ribozyme interaction in the hammerhead ribozyme 1998
• The hydroxyl of threonine 13 of the bovine 70-kDa heat shock cognate protein is essential for transducing the ATP-induced conformational change. 1998
• Thermodynamic stability of the P4-P6 domain RNA tertiary structure measured by temperature gradient gel electrophoresis 1998
• Cysteine and disulfide scanning reveals two amphiphilic helices in the linker region of the aspartate chemoreceptor 1998
• Circular substrates of the hammerhead ribozyme shift the internal equilibrium further toward cleavage 1998
• A semiconserved residue inhibits complex formation by stabilizing interactions in the free state of a theophylline-binding RNA 1998
• Binding of the protein kinase PKR to RNAs with secondary structure defects: Role of the tandem A-G mismatch and noncontiguous helixes 1998
• Participation of the 3‘-CCA of tRNA in the Binding of Catalytic Mg²⁺ Ions by Ribonuclease P 1998
• Euplotes telomerase: Evidence for limited base-pairing during primer elongation and dGTP as an effector of translocation 1998
• Structural variation induced by different nucleotides at the cleavage site of the hammerhead ribozyme 1998
• Deuterium exchange mass spectrometry as a probe of protein kinase activation. Analysis of wild-type and constitutively active mutants of MAP kinase kinase-1 1998
• Kinetic and secondary structure analysis of Naegleria andersoni GIR1, a group I ribozyme whose putative biological function is site-specific hydrolysis 1997
• Ca2+-signaling cycle of a membrane-docking C2 domain 1997
• Optimizing the metal binding parameters of an EF-hand-like calcium chelation loop: Coordinating side chains play a more important tuning role than chelation loop flexibility 1997
• Hammerhead ribozymes with a faster cleavage rate 1997
• Effects of divalent metal ions on individual steps of the Tetrahymena ribozyme reaction 1997
• Eucaryotic DNA primase does not prefer to synthesize primers at pyrimidine rich DNA sequences when nucleoside triphosphates are present at concentrations found in whole cells 1997
• Redox-dependent structural changes in the nitrogenase P-cluster 1997
• A kinetic and thermodynamic analysis of cleavage site mutations in the hammerhead ribozyme 1997
• Uncompetitive substrate inhibition and noncompetitive inhibition by 5-n-undecyl-6-hydroxy-4,7-dioxobenzothiazole (UHDBT) and 2-n-Nonyl-4-hydroxyquinoline-N-oxide (NQNO) is observed for the cytochrome bo(3) complex: Implications for a Q(H-2)-loop proton translocation mechanism 1997
• A conformational change in the catalytic core of the hammerhead ribozyme upon cleavage of an RNA substrate 1997
• Interdependent domains controlling the enzymatic activity of mitogen-activated protein kinase kinase 1 1996
• Mutations in the Tetrahymena ribozyme internal guide sequence: Effects on docking of the P1 helix into the catalytic core and correlation with catalytic activity 1996
• Effects of protein stabilizing agents on thermal backbone motions: A disulfide trapping study 1996
• Minor-groove recognition of double-stranded RNA by the double-stranded RNA-binding domain from the RNA-activated protein kinase PKR 1996
• Biochemical and physicochemical properties of phosphorodithioate DNA 1996
• Inhibitory RNA ligand to reverse transcriptase from feline immunodeficiency virus 1996
• Tuning the equilibrium ion affinity and selectivity of the EF-hand calcium binding motif: Substitutions at the gateway position 1996
• Conformational switches involved in orchestrating the successive steps of group I RNA splicing 1996
• In vitro selection of RNA specifically cleaved by bacteriophage T4 RegB endonuclease 1996
• Kinetic tuning of the EF-Hand calcium binding motif: The gateway residue independently adjusts (I) barrier height and (II) equilibrium 1996
• Exocyclic amine of the conserved G center dot U pair at the cleavage site of the Tetrahymena ribozyme contributes to 5'-splice site selection and transition state stabilization 1996
• Exploration of the Relationship between Tetrachlorohydroquinone Dehalogenase and the Glutathione S-Transferase Superfamily 1996
• SELECTION AND CHARACTERIZATION OF RNAS REPLICATED BY Q-BETA REPLICASE 1995
• TEMPLATE RECOGNITION BY AN RNA-DEPENDENT RNA-POLYMERASE - IDENTIFICATION AND CHARACTERIZATION OF 2 RNA-BINDING SITES ON Q-BETA REPLICASE 1995
• DIVALENT METAL-IONS AND THE INTERNAL EQUILIBRIUM OF THE HAMMERHEAD RIBOZYME 1995
• SOLUTION STRUCTURE OF THE CUUG HAIRPIN LOOP - A NOVEL RNA TETRALOOP MOTIF 1995
• SOLUTION STRUCTURE OF BOVINE NEUTROPHIL BETA-DEFENSIN-12 - THE PEPTIDE FOLD OF THE BETA-DEFENSINS IS IDENTICAL TO THAT OF THE CLASSICAL DEFENSINS 1995
• THE ROLE OF 2'-HYDROXYL GROUPS IN AN RNA-PROTEIN INTERACTION 1995
• ARABINOFURANOSYL NUCLEOTIDES ARE NOT CHAIN-TERMINATORS DURING INITIATION OF NEW STRANDS OF DNA BY DNA-POLYMERASE ALPHA-PRIMASE 1995
• NEOMYCIN INHIBITION OF THE HAMMERHEAD RIBOZYME INVOLVES IONIC INTERACTIONS 1995
• MUTANTS OF THE BACTERIOPHAGE-MS2 COAT PROTEIN THAT ALTER ITS COOPERATIVE BINDING TO RNA 1995
• TRANSMEMBRANE SIGNALING BY THE ASPARTATE RECEPTOR - ENGINEERED DISULFIDES REVEAL STATIC REGIONS OF THE SUBUNIT INTERFACE 1995
• HIGH-AFFINITY SSDNA INHIBITORS OF THE REVERSE-TRANSCRIPTASE OF TYPE-1 HUMAN-IMMUNODEFICIENCY-VIRUS 1995
• EFFICIENT PROTEIN-FACILITATED SPLICING OF THE YEAST MITOCHONDRIAL BI5 INTRON 1995
• PROTON NMR AND STRUCTURAL FEATURES OF A 24-NUCLEOTIDE RNA HAIRPIN 1995
• IN-VITRO SELECTION OF RNA LIGANDS TO SUBSTANCE-P 1995
• A POSITIVE ENTROPY CHANGE FOR GUANOSINE BINDING AND FOR THE CHEMICAL STEP IN THE TETRAHYMENA RIBOZYME REACTION 1995
• HIGH-AFFINITY RNA LIGANDS TO ESCHERICHIA-COLI RIBOSOMES AND RIBOSOMAL-PROTEIN S1 - COMPARISON OF NATURAL AND UNNATURAL BINDING-SITES 1995
• LARGE-AMPLITUDE TWISTING MOTIONS OF AN INTERDOMAIN HINGE - A DISULFIDE TRAPPING STUDY OF THE GALACTOSE-GLUCOSE BINDING-PROTEIN 1995
• ACYCLIC GUANOSINE ANALOGS INHIBIT DNA POLYMERASE-ALPHA, POLYMERASE-DELTA, POLYMERASE-EPSILON WITH VERY DIFFERENT POTENCIES AND HAVE UNIQUE MECHANISMS OF ACTION 1995
• DEFINING A SMALLER RNA SUBSTRATE FOR ELONGATION-FACTOR TU 1995
• DETERMINATION OF V-MOS-CATALYZED PHOSPHORYLATION SITES AND AUTOPHOSPHORYLATION SITES ON MAP KINASE KINASE BY ESI/MS 1995
• THE INTERNAL EQUILIBRIUM OF THE HAMMERHEAD RIBOZYME REACTION 1995
• CATALYSIS OF RNA CLEAVAGE BY A RIBOZYME DERIVED FROM THE GROUP-I INTRON OF ANABAENA PRE-TRNA(LEU) 1994
• REPLACEMENT OF THE CONSERVED G-CENTER-DOT-U WITH A G-C PAIR AT THE CLEAVAGE SITE OF THE TETRAHYMENA RIBOZYME DECREASES BINDING, REACTIVITY, AND FIDELITY 1994
• THE 2,6-DIAMINOPURINE RIBOSIDE-CENTER-DOT-5-METHYLISOCYTIDINE WOBBLE BASE-PAIR - AN ISOENERGETIC SUBSTITUTION FOR THE STUDY OF G-CENTER-DOT-U PAIRS IN RNA 1994
• Purification and Characterization of 4-Chlorobenzoyl CoA Dehalogenase from Arthrobacter sp. Strain 4-CB1 1994
• Rational Design of Self-Cleaving pre-tRNA-Ribonuclease P RNA Conjugates 1994
• PROPERTIES OF AN IN-VITRO SELECTED PB2+ CLEAVAGE MOTIF 1994
• SELECTION OF HIGH-AFFINITY RNA LIGANDS TO REVERSE-TRANSCRIPTASE - INHIBITION OF CDNA SYNTHESIS AND RNASE-H ACTIVITY 1994
• ATTRACTANT-INDUCED AND DISULFIDE-INDUCED CONFORMATIONAL-CHANGES IN THE LIGAND-BINDING DOMAIN OF THE CHEMOTAXIS ASPARTATE RECEPTOR - A F-19 NMR-STUDY 1994
• A KINETIC AND THERMODYNAMIC FRAMEWORK FOR THE HAMMERHEAD RIBOZYME REACTION 1994
• TELOMERIC PROTEIN-DNA POINT CONTACTS IDENTIFIED BY PHOTO-CROSS-LINKING USING 5-BROMODEOXYURIDINE 1994
• CALF THYMUS DNA-POLYMERASE ALPHA-PRIMASE - COMMUNICATION AND PRIMER-TEMPLATE MOVEMENT BETWEEN THE 2 ACTIVE-SITES 1994
• TERTIARY INTERACTIONS WITH THE INTERNAL GUIDE SEQUENCE MEDIATE DOCKING OF THE P1 HELIX INTO THE CATALYTIC CORE OF THE TETRAHYMENA RIBOZYME 1993
• USING CIRCULAR PERMUTATION ANALYSIS TO REDEFINE THE R17 COAT PROTEIN-BINDING SITE 1993
• EVIDENCE FOR THE ROLE OF SOLVATED METAL HYDROXIDE IN THE HAMMERHEAD CLEAVAGE MECHANISM 1993
• CHARACTERIZATION OF A G-QUARTET FORMATION REACTION PROMOTED BY THE BETA-SUBUNIT OF THE OXYTRICHA TELOMERE-BINDING PROTEIN 1993
• NATURE OF THE RIBOSOMAL MESSENGER-RNA TRACK - ANALYSIS OF RIBOSOME-BINDING SITES CONTAINING DIFFERENT SEQUENCES AND SECONDARY STRUCTURES 1993
• DNA POLYMERASE-EPSILON - APHIDICOLIN INHIBITION AND THE RELATIONSHIP BETWEEN POLYMERASE AND EXONUCLEASE ACTIVITY 1993
• CONTRIBUTIONS OF 2'-HYDROXYL GROUPS OF THE RNA SUBSTRATE TO BINDING AND CATALYSIS BY THE TETRAHYMENA RIBOZYME - AN ENERGETIC PICTURE OF AN ACTIVE-SITE COMPOSED OF RNA 1993
• THE IMPORTANCE OF BEING RIBOSE AT THE CLEAVAGE SITE IN THE TETRAHYMENA RIBOZYME REACTION 1993
• SELF-SPLICING OF THE GROUP-I INTRON FROM ANABAENA PRE-TRANSFER-RNA - REQUIREMENT FOR BASE-PAIRING OF THE EXONS IN THE ANTICODON STEM 1993
• IN-VITRO ANALYSIS OF TRANSLATIONAL RATE AND ACCURACY WITH AN UNMODIFIED TRANSFER-RNA 1993
• AN INDEPENDENTLY FOLDING DOMAIN OF RNA TERTIARY STRUCTURE WITHIN THE TETRAHYMENA RIBOZYME 1993
• Multiple magnesium ions in the ribonuclease P reaction mechanism 1993
• NOVEL ION SPECIFICITY OF A CARBOXYLATE CLUSTER MG(II) BINDING-SITE - STRONG CHARGE SELECTIVITY AND WEAK SIZE SELECTIVITY 1993
• MECHANISM OF CALF THYMUS DNA PRIMASE - SLOW INITIATION, RAPID POLYMERIZATION, AND INTELLIGENT TERMINATION 1993
• KINETICS OF INTERMOLECULAR CLEAVAGE BY HAMMERHEAD RIBOZYMES 1992
• NMR-STUDIES OF DEFENSIN ANTIMICROBIAL PEPTIDES .1. RESONANCE ASSIGNMENT AND SECONDARY STRUCTURE DETERMINATION OF RABBIT NP-2 AND HUMAN HNP-1 1992
• NMR-STUDIES OF DEFENSIN ANTIMICROBIAL PEPTIDES .2. 3-DIMENSIONAL STRUCTURES OF RABBIT NP-2 AND HUMAN HNP-1 1992
• DETERMINATION OF RECOGNITION NUCLEOTIDES FOR ESCHERICHIA-COLI PHENYLALANYL-TRANSFER RNA-SYNTHETASE 1992
• INHIBITION OF DNA PRIMASE AND POLYMERASE-ALPHA BY ARABINOFURANOSYLNUCLEOSIDE TRIPHOSPHATES AND RELATED-COMPOUNDS 1992
• RECOGNITION OF YEAST TRANSFER RNA(PHE) BY ITS COGNATE YEAST PHENYLALANYL-TRANSFER RNA-SYNTHETASE - AN ANALYSIS OF SPECIFICITY 1992
• INVITRO SELECTION OF RNAS THAT UNDERGO AUTOLYTIC CLEAVAGE WITH PB2+ 1992
• In vitro selection of RNAs that undergo autolytic cleavage with Pb2+. 1992
• RECOGNITION OF TERTIARY STRUCTURE IN TRANSFER-RNAS BY RH(PHEN)2PHI3+, A NEW REAGENT FOR RNA STRUCTURE-FUNCTION MAPPING 1992
• Contributions of phylogenetically variable structural elements to the function of the ribozyme ribonuclease P 1992
• ROLE OF DIVALENT METAL-IONS IN THE HAMMERHEAD RNA CLEAVAGE REACTION 1991
• Mechanism of DNA polymerase .alpha. inhibition by aphidicolin 1991
• QUANTITATING AND ENGINEERING THE ION SPECIFICITY OF AN EF-HAND-LIKE CA2+ BINDING-SITE 1991
• SEQUENCE-SPECIFIC H-1-NMR ASSIGNMENTS, SECONDARY STRUCTURE, AND LOCATION OF THE CALCIUM-BINDING SITE IN THE 1ST EPIDERMAL GROWTH-FACTOR LIKE DOMAIN OF BLOOD-COAGULATION FACTOR-IX 1991
• COMPARISON OF OPERATOR-SPECIFIC AND NONSPECIFIC DNA-BINDING OF THE LAMBDA-CI REPRESSOR - [KC1] AND PH EFFECTS 1991
• OPEN CONFORMATION OF A SUBSTRATE-BINDING CLEFT - F-19 NMR-STUDIES OF CLEFT ANGLE IN THE D-GALACTOSE CHEMOSENSORY RECEPTOR 1991
• A SPECIFIC, UV-INDUCED RNA PROTEIN CROSS-LINK USING 5-BROMOURIDINE-SUBSTITUTED RNA 1991
• RIBOZYME-CATALYZED AND NONENZYMATIC REACTIONS OF PHOSPHATE DIESTERS - RATE EFFECTS UPON SUBSTITUTION OF SULFUR FOR A NONBRIDGING PHOSPHORYL OXYGEN ATOM 1991
• F-19 NMR-STUDIES OF THE D-GALACTOSE CHEMOSENSORY RECEPTOR .1. SUGAR BINDING YIELDS A GLOBAL STRUCTURAL-CHANGE 1991
• F-19 NMR-STUDIES OF THE D-GALACTOSE CHEMOSENSORY RECEPTOR .1. SUGAR BINDING YIELDS A GLOBAL STRUCTURAL-CHANGE 1991
• F-19 NMR-STUDIES OF THE D-GALACTOSE CHEMOSENSORY RECEPTOR .2. CA(II) BINDING YIELDS A LOCAL STRUCTURAL-CHANGE 1991
• F-19 NMR-STUDIES OF THE D-GALACTOSE CHEMOSENSORY RECEPTOR .2. CA(II) BINDING YIELDS A LOCAL STRUCTURAL-CHANGE 1991
• AUTONOMOUS FOLDING AND COENZYME BINDING OF THE EXCISED PYRIDOXAL 5'-PHOSPHATE BINDING DOMAIN OF ASPARTATE-AMINOTRANSFERASE FROM ESCHERICHIA-COLI 1991
• ALTERNATIVE SECONDARY STRUCTURES IN THE 5' EXON AFFECT BOTH FORWARD AND REVERSE SELF-SPLICING OF THE TETRAHYMENA INTERVENING SEQUENCE RNA 1991
• MECHANISM OF DNA-REPLICATION FIDELITY FOR 3 MUTANTS OF DNA-POLYMERASE-I - KLENOW FRAGMENT KF(EXO+), KF(POLA5), AND KF(EXO-) 1991
• INHIBITION OF DNA PRIMASE BY 9-BETA-D-ARABINOFURANOSYLADENOSINE TRIPHOSPHATE 1991
• COOPERATIVE BINDING OF R17 COAT PROTEIN TO RNA 1990
• SEQUENCE REQUIREMENTS OF THE HAMMERHEAD RNA SELF-CLEAVAGE REACTION 1990
• THE SELF-SPLICING RNA OF TETRAHYMENA IS TRAPPED IN A LESS ACTIVE CONFORMATION BY GEL PURIFICATION 1990
• CATALYSIS OF RNA CLEAVAGE BY THE TETRAHYMENA-THERMOPHILA RIBOZYME .1. KINETIC DESCRIPTION OF THE REACTION OF AN RNA SUBSTRATE COMPLEMENTARY TO THE ACTIVE-SITE 1990
• CATALYSIS OF RNA CLEAVAGE BY THE TETRAHYMENA-THERMOPHILA RIBOZYME .2. KINETIC DESCRIPTION OF THE REACTION OF AN RNA SUBSTRATE THAT FORMS A MISMATCH AT THE ACTIVE-SITE 1990
• ROLE OF THE CRO REPRESSOR CARBOXY-TERMINAL DOMAIN AND FLEXIBLE DIMER LINKAGE IN OPERATOR AND NONSPECIFIC DNA-BINDING 1990
• Reduction of the potent DNA polymerase III holoenzyme 3'----5' exonuclease activity by template-primer analogues. 1990
• AN ULTRAVIOLET-INDUCIBLE ADENOSINE ADENOSINE CROSS-LINK REFLECTS THE CATALYTIC STRUCTURE OF THE TETRAHYMENA RIBOZYME 1990
• CALCIUM(II) SITE SPECIFICITY - EFFECT OF SIZE AND CHARGE ON METAL-ION BINDING TO AN EF-HAND-LIKE SITE 1990
• LEAD-CATALYZED CLEAVAGE OF YEAST TRANSFER RNAPHE MUTANTS 1990
• ROLE OF THE TERTIARY NUCLEOTIDES IN THE INTERACTION OF YEAST PHENYLALANINE TRANSFER-RNA WITH ITS COGNATE SYNTHETASE 1990
• THE MECHANISM OF KLENOW FRAGMENT MISINCORPORATION 1990
• EARLY PHOTOLYSIS INTERMEDIATES OF THE ARTIFICIAL VISUAL PIGMENT 13-DEMETHYLRHODOPSIN 1990
• IRON(II)-ETHYLENEDIAMINETETRAACETIC ACID-CATALYZED CLEAVAGE OF RNA AND DNA OLIGONUCLEOTIDES - SIMILAR REACTIVITY TOWARD SINGLE-STRANDED AND DOUBLE-STRANDED FORMS 1990
• NANOSECOND PHOTOLYSIS OF RHODOPSIN - EVIDENCE FOR A NEW, BLUE-SHIFTED INTERMEDIATE 1990
• SOLUTION STRUCTURES OF PROTEINS FROM NMR DATA AND MODELING - ALTERNATIVE FOLDS FOR NEUTROPHIL PEPTIDE-5 1989
• LIMITED SAMPLING OF CONFORMATIONAL SPACE BY THE DISTANCE GEOMETRY ALGORITHM - IMPLICATIONS FOR STRUCTURES GENERATED FROM NMR DATA 1989
• METAL-ION REQUIREMENTS FOR SEQUENCE-SPECIFIC ENDORIBONUCLEASE ACTIVITY OF THE TETRAHYMENA RIBOZYME 1989
• STRUCTURE OF AN UNMODIFIED TRANSFER-RNA MOLECULE 1989
• SOLUTION STRUCTURES OF ALPHA-CONOTOXIN-G1 DETERMINED BY TWO-DIMENSIONAL NMR-SPECTROSCOPY 1989
• DETERMINATION OF RNA PROTEIN CONTACTS USING THIOPHOSPHATE SUBSTITUTIONS 1989
• PROPERTIES OF THE TELOMERIC DNA-BINDING PROTEIN FROM OXYTRICHA-NOVA 1989
• THERMAL-STABILITY OF RNA HAIRPINS CONTAINING A 4-MEMBERED LOOP AND A BULGE NUCLEOTIDE 1989
• SPECIFIC RNA-BINDING BY Q-BETA COAT PROTEIN 1989
• SEQUENCE-SPECIFIC ENDORIBONUCLEASE ACTIVITY OF THE TETRAHYMENA RIBOZYME - ENHANCED CLEAVAGE OF CERTAIN OLIGONUCLEOTIDE SUBSTRATES THAT FORM MISMATCHED RIBOZYME SUBSTRATE COMPLEXES 1988
• The dimer of the beta subunit of Escherichia coli DNA polymerase III holoenzyme is dissociated into monomers upon binding magnesium(II). 1988
• Kinetics and thermodynamics of the interaction of 5-fluoro-2'-deoxyuridylate with thymidylate synthase. 1987
• ROLE OF A BULGED-A RESIDUE IN A SPECIFIC RNA PROTEIN-INTERACTION 1987
• Kinetic mechanism of DNA polymerase I (Klenow) 1987
• Two-dimensional NMR studies of the antimicrobial peptide NP-5 1987
• GUANOSINE BINDING REQUIRED FOR CYCLIZATION OF THE SELF-SPLICING INTERVENING SEQUENCE RIBONUCLEIC-ACID FROM TETRAHYMENA-THERMOPHILA 1987
• RNA-BINDING SITE OF R17 COAT PROTEIN 1987
• POLYMER-SUPPORTED RNA-SYNTHESIS AND ITS APPLICATION TO TEST THE NEAREST-NEIGHBOR MODEL FOR DUPLEX STABILITY 1986
• Iron-sulfur centers in lactyl-CoA dehydratase 1986
• SPECIFIC SUBSTITUTION INTO THE ANTICODON LOOP OF YEAST TYROSINE TRANSFER-RNA 1986
• RIBOZYME INHIBITORS - DEOXYGUANOSINE AND DIDEOXYGUANOSINE ARE COMPETITIVE INHIBITORS OF SELF-SPLICING OF THE TETRAHYMENA RIBOSOMAL RIBONUCLEIC-ACID PRECURSOR 1986
• THE TETRAHYMENA INTERVENING SEQUENCE RIBONUCLEIC-ACID ENZYME IS A PHOSPHOTRANSFERASE AND AN ACID-PHOSPHATASE 1986
• IDENTIFICATION OF THE FIBROBLAST GROWTH-FACTOR RECEPTOR OF SWISS-3T3 CELLS AND MOUSE SKELETAL-MUSCLE MYOBLASTS 1986
• FREE-ENERGY CONTRIBUTIONS OF G.U AND OTHER TERMINAL MISMATCHES TO HELIX STABILITY 1986
• STABILITY OF XGCGCP, GCGCYP, AND XGCGCYP HELIXES - AN EMPIRICAL ESTIMATE OF THE ENERGETICS OF HYDROGEN-BONDS IN NUCLEIC-ACIDS 1986
• CALCIUM-BINDING TO COMPLEXES OF CALMODULIN AND CALMODULIN BINDING-PROTEINS 1985
• Nucleoside and nucleotide inactivation of R17 coat protein: evidence for a transient covalent RNA-protein bond. 1985
• Specific replacement of functional groups of uridine-33 in yeast phenylalanine transfer ribonucleic acid. 1985
• Aminoacylation of anticodon loop substituted yeast tyrosine transfer RNA. 1985
• NEW CHEMICAL METHODS FOR SYNTHESIZING DNA AND RNA 1985
• REACTIONS OF THE INTERVENING SEQUENCE OF THE TETRAHYMENA RIBOSOMAL RIBONUCLEIC-ACID PRECURSOR - PH-DEPENDENCE OF CYCLIZATION AND SITE-SPECIFIC HYDROLYSIS 1985
• SELF-SPLICING RNA 1985
• Chemically induced dynamic nuclear polarization studies of guanosine in nucleotides, dinucleotides, and oligonucleotides 1984
• BIOCHEMICAL-STUDIES USING SYNTHETIC DNA 1984
• STUDIES ON GENE-CONTROL REGIONS .15. INTERACTION OF AD2+D2 PROTEIN AND SIMIAN VIRUS-40 LARGE T-ANTIGEN WITH THE LARGE TUMOR-ANTIGEN BINDING SITE-I 1984
• Site-specific pausing of deoxyribonucleic acid synthesis catalyzed by four forms of Escherichia coli DNA polymerase III. 1983
• Interaction of R17 coat protein with synthetic variants of its ribonucleic acid binding site. 1983
• Mechanism of modulation of dopamine .beta.-monooxygenase by pH and fumarate as deduced from initial rate and primary deuterium isotope effect studies 1983
• Kinetic and thermodynamic characterization of the R17 coat protein-ribonucleic acid interaction. 1983
• Sequence-specific interaction of R17 coat protein with its ribonucleic acid binding site. 1983
• Kinetics for exchange of the imino protons of the d(C-G-C-G-A-A-T-T-C-G-C-G) double helix in complexes with the antibiotics netropsin and/or actinomycin 1983
• FATE OF AN INTERVENING SEQUENCE RIBONUCLEIC-ACID - EXCISION AND CYCLIZATION OF THE TETRAHYMENA RIBOSOMAL RIBONUCLEIC-ACID INTERVENING SEQUENCE INVIVO 1983
• IMMUNOAFFINITY PURIFICATION AND CHARACTERIZATION OF 5-[[[(IODOACETYL)AMINO]ETHYL]AMINO]NAPHTHALENE-1-SULFONIC ACID DERIVATIZED CALMODULIN 1983
• Enzymatic synthesis of a 21-nucleotide coat protein binding fragment of R17 ribonucleic acid. 1982
• Kinetics for exchange of imino protons in deoxyribonucleic acid, ribonucleic acid, and hybrid oligonucleotide helixes 1982
• Specific interaction of anticodon loop residues with yeast phenylalanyl-tRNA synthetase. 1982
• Enzymic and chemical structure mapping of mouse 28S ribosomal RNA-contacts in 5.8S ribosomal RNA 1982
• Independent binding sites in mouse 5.8S ribosomal RNA for 28S ribosomal RNA 1982
• Structural effects on the circular dichroism of ethidium ion nucleic acid complexes 1982
• Reversal of T4 RNA ligase. 1982
• Enzymatic replacement of the anticodon of yeast phenylalanine transfer ribonucleic acid. 1982
• DETERMINATION OF THE FREE-ENERGY COUPLING FOR BINDING OF CALCIUM-IONS AND TROPONIN-I TO CALMODULIN 1982
• INTERACTION OF A FLUORESCENT N-DANSYLAZIRIDINE DERIVATIVE OF TROPONIN-I WITH CALMODULIN IN THE ABSENCE AND PRESENCE OF CALCIUM 1982
• UNUSUAL ZWITTERION OF D,L-BETA-CARBOXYASPARTIC ACID - PKA AND X-RAY CRYSTALLOGRAPHIC MEASUREMENTS 1982
• Comparative study of ribonucleotides, deoxyribonucleotides, and hybrid oligonucleotide helixes by nuclear magnetic resonance 1981
• ALKALINE GEL-ELECTROPHORESIS OF DEOXYRIBONUCLEIC-ACID PHOTOREACTED WITH TRIMETHYLPSORALEN - RAPID AND SENSITIVE DETECTION OF INTERSTRAND CROSS-LINKS 1981
• PREPARATION OF A FLUORESCENT-LABELED DERIVATIVE OF CALMODULIN WHICH RETAINS ITS AFFINITY FOR CALMODULIN BINDING-PROTEINS 1981
• Interaction of Escherichia coli host factor protein with Q beta ribonucleic acid. 1980
• Interaction of Escherichia coli host factor protein with oligoriboadenylates. 1980
• A METHOD FOR LINKING FLUORESCENT LABELS TO POLYNUCLEOTIDES - APPLICATION TO STUDIES OF RIBOSOME-RIBONUCLEIC ACID INTERACTIONS 1980
• Bohr effect in Escherichia coli aspartate transcarbamylase. Linkages between substrate binding, proton binding, and conformational transitions. 1979
• Involvement of the mature domain in the in vitro maturation of Bacillus subtilis precursor 5S ribosomal RNA 1978
• Enzymatic oligoribonucleotide synthesis with T4 RNA ligase. 1978
• Synthesis of modified nucleoside 3',5'-bisphosphates and their incorporation into oligoribonucleotides with T4 RNA ligase. 1978
• 3'-Phosphatase activity in T4 polynucleotide kinase. 1977
• Involvement of precursor-specific segments in the in vitro maturation of Bacillus subtilis precursor 5S ribosomal RNA 1977
• Electron microscopy of DNA crosslinked with trimethylpsoralen: a probe for chromatin structure 1977
• Structure of the 5.8S RNA component of the 5.8S-28S ribosomal RNA junction complex 1977
• STUDIES ON GENE CONTROL REGIONS .1. CHEMICAL SYNTHESIS OF LACTOSE OPERATOR DEOXYRIBONUCLEIC-ACID SEGMENTS 1977
• STUDIES ON GENE CONTROL REGIONS .2. ENZYMATIC JOINING OF CHEMICALLY SYNTHESIZED LACTOSE OPERATOR DEOXYRIBONUCLEIC-ACID SEGMENTS 1977
• SYNTHESIS AND BIOLOGICAL-ACTIVITY OF A LAMBDA-PSEUDO OPERATOR 1977
• PARTIAL DENATURATION OF MOUSE DNA IN PREPARATIVE CSCL DENSITY GRADIENTS AT ALKALINE PH 1976
• Renaturation of a multisubunit multiactivity enzyme complex: recovery of phage Qβ RNA replicase, EF-Tu, and EF-Ts activities after denaturation in urea 1976
• Stepwise enzymatic oligoribonucleotide synthesis including modified nucleotides. 1975
• A filter assay for thymidylate synthetase using 5-fluoro-2'-deoxyuridylate as an active site titrant. 1974
• Mechanism of interaction of thymidylate synthetase with 5-fluorodeoxyuridylate. 1974
• Circular dichroism study of nine species of transfer ribonucleic acid. 1972
• Binding of complementary oligonucleotides to free and aminoacyl transfer ribonucleic acid synthetase bound transfer ribonucleic acid. 1972
• Reactions of Nucleosides on Polymer Supports. Synthesis of Thymidylylthymidylylthymidine^* 1967

Research

keywords

• 0601 Biochemistry and Cell Biology, 1101 Medical Biochemistry and Metabolomics, 0304 Medicinal and Biomolecular Chemistry