RNA, Untranslated - RNA, Catalytic | CU Experts

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In Crystallo Selection to Establish New RNA Crystal Contacts Journal Article
A CONSERVED BASE PAIR WITHIN HELIX-P4 OF THE TETRAHYMENA RIBOZYME HELPS TO FORM THE TERTIARY STRUCTURE REQUIRED FOR SELF-SPLICING Journal Article
A HAMMERHEAD RIBOZYME ALLOWS SYNTHESIS OF A NEW FORM OF THE TETRAHYMENA RIBOZYME HOMOGENEOUS IN LENGTH WITH A 3' END BLOCKED FOR TRANSESTERIFICATION Journal Article
A KINETIC AND THERMODYNAMIC FRAMEWORK FOR THE HAMMERHEAD RIBOZYME REACTION Journal Article
A POSITIVE ENTROPY CHANGE FOR GUANOSINE BINDING AND FOR THE CHEMICAL STEP IN THE TETRAHYMENA RIBOZYME REACTION Journal Article
A SELF-SPLICING GROUP-I INTRON IN THE NUCLEAR PRE-RIBOSOMAL-RNA OF THE GREEN-ALGA, ANKISTRODESMUS-STIPITATUS Journal Article
A SMALL CATALYTIC OLIGORIBONUCLEOTIDE Journal Article
A SMALL METALLORIBOZYME WITH A 2-STEP MECHANISM Journal Article
A TERTIARY INTERACTION IN THE TETRAHYMENA INTRON CONTRIBUTES TO SELECTION OF THE 5' SPLICE-SITE Journal Article
A TETRAHYMENA INTRON NUCLEOTIDE CONNECTED TO THE GTP ARGININE SITE Journal Article
A conformational change in the catalytic core of the hammerhead ribozyme upon cleavage of an RNA substrate Journal Article
A covalent crosslink converts the hammerhead ribozyme from a ribonuclease to an RNA ligase Journal Article
A kinetic and thermodynamic analysis of cleavage site mutations in the hammerhead ribozyme Journal Article
A natural ribozyme with 3 ',5 ' RNA ligase activity Journal Article
A preorganized active site in the crystal structure of the Tetrahymena ribozyme Journal Article
A re-investigation of the thio effect at the hammerhead cleavage site Journal Article
A second catalytic metal ion in a group I ribozyme Journal Article
A universal mode of helix packing in RNA Journal Article
ALTERATION OF SUBSTRATE-SPECIFICITY FOR THE ENDORIBONUCLEOLYTIC CLEAVAGE OF RNA BY THE TETRAHYMENA RIBOZYME Journal Article
AMINOACYL ESTERASE-ACTIVITY OF THE TETRAHYMENA RIBOZYME Journal Article
AN IMPORTANT RNA TERTIARY INTERACTION OF GROUP-I AND GROUP-II INTRONS IS IMPLICATED IN GRAM-POSITIVE RNASE-P RNAS Journal Article
AN INDEPENDENTLY FOLDING DOMAIN OF RNA TERTIARY STRUCTURE WITHIN THE TETRAHYMENA RIBOZYME Journal Article
AN ULTRAVIOLET-INDUCIBLE ADENOSINE ADENOSINE CROSS-LINK REFLECTS THE CATALYTIC STRUCTURE OF THE TETRAHYMENA RIBOZYME Journal Article
ANALYSIS OF THE STRUCTURE OF TETRAHYMENA NUCLEAR RNAS IN-VIVO - TELOMERASE RNA, THE SELF-SPLICING RIBOSOMAL-RNA INTRON, AND U2 SNRNA Journal Article
Active site dynamics in the lead-dependent ribozyme Journal Article
An RNA internal loop acts as a hinge to facilitate ribozyme folding and catalysis Journal Article
An early transition state for folding of the P4-P6 RNA domain Journal Article
Assembly of a ribonucleoprotein catalyst by tertiary structure capture Journal Article
Atomic level architecture of group I introns revealed Journal Article
Base and sugar requirements for RNA cleavage of essential nucleoside residues in internal loop B of the hairpin ribozyme: Implications for secondary structure Journal Article
CATALYSIS OF RNA CLEAVAGE BY A RIBOZYME DERIVED FROM THE GROUP-I INTRON OF ANABAENA PRE-TRNA(LEU) Journal Article
CATALYSIS OF RNA CLEAVAGE BY THE TETRAHYMENA-THERMOPHILA RIBOZYME .1. KINETIC DESCRIPTION OF THE REACTION OF AN RNA SUBSTRATE COMPLEMENTARY TO THE ACTIVE-SITE Journal Article
CATALYSIS OF RNA CLEAVAGE BY THE TETRAHYMENA-THERMOPHILA RIBOZYME .2. KINETIC DESCRIPTION OF THE REACTION OF AN RNA SUBSTRATE THAT FORMS A MISMATCH AT THE ACTIVE-SITE Journal Article
CATALYTIC RNA - STRUCTURE AND MECHANISM Journal Article
CHARACTERIZATION OF DEOXY-CONTAINING AND RIBO-CONTAINING OLIGONUCLEOTIDE SUBSTRATES IN THE HAMMERHEAD SELF-CLEAVAGE REACTION Journal Article
CIRCULARLY PERMUTED TRANSFER-RNAS AS SPECIFIC PHOTOAFFINITY PROBES OF RIBONUCLEASE-P RNA STRUCTURE Journal Article
COAXIALLY STACKED RNA HELICES IN THE CATALYTIC CENTER OF THE TETRAHYMENA RIBOZYME Journal Article
CONSERVED SEQUENCES AND STRUCTURES OF GROUP-I INTRONS - BUILDING AN ACTIVE-SITE FOR RNA CATALYSIS - A REVIEW Journal Article
CONTRIBUTIONS OF 2'-HYDROXYL GROUPS OF THE RNA SUBSTRATE TO BINDING AND CATALYSIS BY THE TETRAHYMENA RIBOZYME - AN ENERGETIC PICTURE OF AN ACTIVE-SITE COMPOSED OF RNA Journal Article
Catalytic diversity of extended hammerhead ribozymes. Journal Article
Circular substrates of the hammerhead ribozyme shift the internal equilibrium further toward cleavage Journal Article
Comparison of crystal structure interactions and thermodynamics for stabilizing mutations in the Tetrahymena ribozyme Journal Article
Comparison of the hammerhead cleavage reactions stimulated by monovalent and divalent cations Journal Article
Conserved thermochemistry of guanosine nucleophile binding for structurally distinct group I ribozymes Journal Article
Correlation of the guanosine exchangeable and nonexchangeable base protons in C-13-(IN)-N-15-labeled RNA with an HNC-TOCSY-CH experiment Journal Article
Crawling Out of the RNA World Journal Article
Cryoenzymology of the hammerhead ribozyme Journal Article
Crystal structure of a bacterial ribonuclease P RNA Journal Article
Crystal structure of a group I ribozyme domain: Principles of RNA packing Journal Article
Crystals by design: A strategy for crystallization of a ribozyme derived from the Tetrahymena group I intron Journal Article
DEFINING THE INSIDE AND OUTSIDE OF A CATALYTIC RNA MOLECULE Journal Article
DIRECT MEASUREMENT OF OLIGONUCLEOTIDE SUBSTRATE BINDING TO WILD-TYPE AND MUTANT RIBOZYMES FROM TETRAHYMENA Journal Article
DIVALENT METAL-IONS AND THE INTERNAL EQUILIBRIUM OF THE HAMMERHEAD RIBOZYME Journal Article
DIVERSITY OF OLIGONUCLEOTIDE FUNCTIONS Journal Article
DNA CLEAVAGE CATALYZED BY THE RIBOZYME FROM TETRAHYMENA Journal Article
EVIDENCE FOR THE ROLE OF SOLVATED METAL HYDROXIDE IN THE HAMMERHEAD CLEAVAGE MECHANISM Journal Article
Effects of divalent metal ions on individual steps of the Tetrahymena ribozyme reaction Journal Article
Efficient ligation of the Schistosoma hammerhead ribozyme Journal Article
Energetics and cooperativity of tertiary hydrogen bonds in RNA structure Journal Article
Enhanced product stability in the hammerhead ribozyme. Journal Article
Evolution of Biological Catalysis: Ribozyme to RNP Enzyme Journal Article
Evolution of Tetrahymena ribozyme mutants with increased structural stability Journal Article
Exocyclic amine of the conserved G center dot U pair at the cleavage site of the Tetrahymena ribozyme contributes to 5'-splice site selection and transition state stabilization Journal Article
Expression, purification, crystallization and preliminary diffraction analysis of RNase P protein from Thermotoga maritima Journal Article
FOLDING OF GROUP-I INTRONS FROM BACTERIOPHAGE-T4 INVOLVES INTERNALIZATION OF THE CATALYTIC CORE Journal Article
Fast cleavage kinetics of a natural hammerhead ribozyme Journal Article
Functional groups on the cleavage site pyrimidine nucleotide are required for stabilization of the hammerhead transition state Journal Article
GUANOSINE BINDING TO THE TETRAHYMENA RIBOZYME - THERMODYNAMIC COUPLING WITH OLIGONUCLEOTIDE BINDING Journal Article
HAMMERHEAD .2. Journal Article
Hammerhead cleavage of the phosphorodithioate linkage Journal Article
Hammerhead redux: does the new structure fit the old biochemical data? Journal Article
Hammerhead ribozyme kinetics Journal Article
Hammerhead ribozymes with a faster cleavage rate Journal Article
Hammerhead: Part 2. Journal Article
Hammerheads derived from sTRSV show enhanced cleavage and ligation rate constants. Journal Article
High-performance liquid chromatography purification of homogenous-length RNA produced by trans cleavage with a hammerhead ribozyme Journal Article
High-resolution structure of RNase P protein from Thermotoga maritima Journal Article
IDENTIFICATION OF RIBOZYMES WITHIN A RIBOZYME LIBRARY THAT EFFICIENTLY CLEAVE A LONG SUBSTRATE RNA Journal Article
IMPROVED MEASUREMENT OF C-13, P-31 J-COUPLING-CONSTANTS IN ISOTOPICALLY LABELED RNA Journal Article
INHIBITION OF THE HAMMERHEAD RIBOZYME BY NEOMYCIN Journal Article
Identification and characterization of a novel high affinity metal-binding site in the hammerhead ribozyme Journal Article
Improved distance analysis in RNA using network-editing techniques for overcoming errors due to spin diffusion Journal Article
Improved native affinity purification of RNA Journal Article
In vitro selection of a novel catalytic RNA: Characterization of a sulfur alkylation reaction and interaction with a small peptide Journal Article
In vitro selection of self-cleaving RNAs with a low pH optimum Journal Article
In vitro selection of the Naegleria GIR1 ribozyme identifies three base changes that dramatically improve activity Journal Article
Inhibition of the hammerhead ribozyme cleavage reaction by site-specific binding of Tb(III) Journal Article
Internal equilibrium of the hammerhead ribozyme is altered by the length of certain covalent cross-links Journal Article
Involvement of a specific metal ion in the transition of the hammerhead ribozyme to its catalytic conformation Journal Article
Joining the two domains of a group I ribozyme to form the catalytic core Journal Article
KINETIC CHARACTERIZATION OF INTRAMOLECULAR AND INTERMOLECULAR HAMMERHEAD RNAS WITH STEM-II DELETIONS Journal Article
KINETICS OF INTERMOLECULAR CLEAVAGE BY HAMMERHEAD RIBOZYMES Journal Article
Kinetic and secondary structure analysis of Naegleria andersoni GIR1, a group I ribozyme whose putative biological function is site-specific hydrolysis Journal Article
Kinetic characterization of two I/II format hammerhead ribozymes Journal Article
Kinetic pathway for folding of the Tetrahymena ribozyme revealed by three UV-inducible crosslinks Journal Article
Linking RNA biology to lncRNAs Journal Article
Local RNA structural changes induced by crystallization are revealed by SHAPE Journal Article
METAL-ION CATALYSIS IN THE TETRAHYMENA RIBOZYME REACTION Journal Article
METAL-ION REQUIREMENTS FOR SEQUENCE-SPECIFIC ENDORIBONUCLEASE ACTIVITY OF THE TETRAHYMENA RIBOZYME Journal Article
MINOR-GROOVE RECOGNITION OF THE CONSERVED G-CENTER-DOT-U PAIR AT THE TETRAHYMENA RIBOZYME REACTION SITE Journal Article
MOVEMENT OF THE GUIDE SEQUENCE DURING RNA CATALYSIS BY A GROUP-I RIBOZYME Journal Article
MUTATIONS AT THE GUANOSINE-BINDING SITE OF THE TETRAHYMENA RIBOZYME ALSO AFFECT SITE-SPECIFIC HYDROLYSIS Journal Article
MUTATIONS IN A NONCONSERVED SEQUENCE OF THE TETRAHYMENA RIBOZYME INCREASE ACTIVITY AND SPECIFICITY Journal Article
Measurement of carbon-phosphorus J coupling constants in RNA using spin-echo difference constant-time HCCH-COSY Journal Article
Metal ion specificities for folding and cleavage activity in the Schistosoma hammerhead ribozyme Journal Article
Modified nucleotidesmay have enhanced early RNA catalysis Journal Article
Monitoring post-translational modification of proteins with allosteric ribozymes Journal Article
Multiple folding pathways for the P4-P6 RNA domain Journal Article
Mutagenesis and comparative sequence analysis of a base triple joining the two domains of group I ribozymes Journal Article
Mutations in the Tetrahymena ribozyme internal guide sequence: Effects on docking of the P1 helix into the catalytic core and correlation with catalytic activity Journal Article
NEOMYCIN INHIBITION OF THE HAMMERHEAD RIBOZYME INVOLVES IONIC INTERACTIONS Journal Article
NMR solution structure of the lead-dependent ribozyme: Evidence for dynamics in RNA catalysis Journal Article
NUCLEAR-MAGNETIC-RESONANCE STUDIES OF THE HAMMERHEAD RIBOZYME DOMAIN - SECONDARY STRUCTURE FORMATION AND MAGNESIUM-ION DEPENDENCE Journal Article
NUMBERING SYSTEM FOR THE HAMMERHEAD Journal Article
Natural and artificial RNAs occupy the same restricted region of sequence space Journal Article
On the occasion of the 25(th) anniversary of the discovery of catalytic RNA Journal Article
Order, dynamics and metal-binding in the lead-dependent ribozyme Journal Article
Peptide bond formation by in vitro selected ribozymes Journal Article
Peptidyl-transferase ribozymes: trans reactions, structural characterization and ribosomal RNA-like features Journal Article
Photoaffinity cross-linking and RNA structure analysis Journal Article
Phylogenetic-comparative analysis of the eukaryal ribonuclease P RNA Journal Article
Probing the binding of Tb(III) and Eu(III) to the hammerhead ribozyme using luminescence spectroscopy Journal Article
Protein activation of a ribozyme: the role of bacterial RNase P protein Journal Article
RELATIVE ORIENTATION OF RNA HELICES IN A GROUP-I RIBOZYME DETERMINED BY HELIX EXTENSION ELECTRON-MICROSCOPY Journal Article
REPLACEMENT OF THE CONSERVED G-CENTER-DOT-U WITH A G-C PAIR AT THE CLEAVAGE SITE OF THE TETRAHYMENA RIBOZYME DECREASES BINDING, REACTIVITY, AND FIDELITY Journal Article
RIBOZYME RECOGNITION OF RNA BY TERTIARY INTERACTIONS WITH SPECIFIC RIBOSE 2'-OH GROUPS Journal Article
RIBOZYME REVEALED Journal Article
RIBOZYME-CATALYZED AND NONENZYMATIC REACTIONS OF PHOSPHATE DIESTERS - RATE EFFECTS UPON SUBSTITUTION OF SULFUR FOR A NONBRIDGING PHOSPHORYL OXYGEN ATOM Journal Article
RIBOZYME-MEDIATED REPAIR OF DEFECTIVE MESSENGER-RNA BY TARGETED TRANSSPLICING Journal Article
RIBOZYMES - HAMMERHEAD NAILED DOWN Journal Article
RNA - FISHING FOR FRESH CATALYSTS Journal Article
RNA AS AN ENZYME Journal Article
RNA AS AN RNA-POLYMERASE - NET ELONGATION OF AN RNA PRIMER CATALYZED BY THE TETRAHYMENA RIBOZYME Journal Article
RNA CATALYSIS BY A GROUP-I RIBOZYME - DEVELOPING A MODEL FOR TRANSITION-STATE STABILIZATION Journal Article
RNA CHEMISTRY - RIBOZYME SELF-REPLICATION Journal Article
RNA SUBSTRATE BINDING-SITE IN THE CATALYTIC CORE OF THE TETRAHYMENA RIBOZYME Journal Article
RNA as the catalyst for drug screening - Reporter ribozymes that allow monitoring of protein-nucleic acid and protein-protein interactions facilitate rapid identification of inhibitors for use in drug discovery. Journal Article
RNA finds a simpler way Journal Article
RNA tertiary folding monitored by fluorescence of covalently attached pyrene Journal Article
RNA tertiary structure mediation by adenosine platforms Journal Article
RNA-Puzzles Round III: 3D RNA structure prediction of five riboswitches and one ribozyme Journal Article
RNA-Puzzles Round IV: 3D structure predictions of four ribozymes and two aptamers Journal Article
ROLE OF DIVALENT METAL-IONS IN THE HAMMERHEAD RNA CLEAVAGE REACTION Journal Article
Rapid and Simple Ribozymic Aminoacylation Using Three Conserved Nucleotides Journal Article
Recurrent RNA motifs as scaffolds for genetically encodable small-molecule biosensors Journal Article
Riboswitches: still a lot of undiscovered country Journal Article
Ribozymes, the first 20 years Journal Article
SELF-ASSEMBLY OF A GROUP-I INTRON ACTIVE-SITE FROM ITS COMPONENT TERTIARY STRUCTURAL DOMAINS Journal Article
SELF-CLEAVING CATALYTIC RNA Journal Article
SELF-SPLICING AND ENZYMATIC CLEAVAGE OF RNA BY A GROUP-I INTERVENING SEQUENCE Journal Article
SELF-SPLICING OF THE GROUP-I INTRON FROM ANABAENA PRE-TRANSFER-RNA - REQUIREMENT FOR BASE-PAIRING OF THE EXONS IN THE ANTICODON STEM Journal Article
SELF-SPLICING RNA AND AN RNA ENZYME IN TETRAHYMENA Journal Article
SEQUENCE REQUIREMENTS OF THE HAMMERHEAD RNA SELF-CLEAVAGE REACTION Journal Article
SEQUENCE-DEPENDENT STRUCTURAL VARIATIONS OF HAMMERHEAD RNA ENZYMES Journal Article
SEQUENCE-SPECIFIC ENDORIBONUCLEASE ACTIVITY OF THE TETRAHYMENA RIBOZYME - ENHANCED CLEAVAGE OF CERTAIN OLIGONUCLEOTIDE SUBSTRATES THAT FORM MISMATCHED RIBOZYME SUBSTRATE COMPLEXES Journal Article
SPECIFICITY FOR 3',5'-LINKED SUBSTRATES IN RNA-CATALYZED RNA POLYMERIZATION Journal Article
STEREOCHEMISTRY OF RNA CLEAVAGE BY THE TETRAHYMENA RIBOZYME AND EVIDENCE THAT THE CHEMICAL STEP IS NOT RATE-LIMITING Journal Article
STUDIES ON THE HAMMERHEAD RNA SELF-CLEAVING DOMAIN Journal Article
SUBSTRATE SEQUENCE EFFECTS ON HAMMERHEAD RNA CATALYTIC EFFICIENCY Journal Article
Self-splicing of group I introns. Journal Article
Self-splicing of the Tetrahymena intron from mRNA in mammalian cells Journal Article
Solution structure of RNase P RNA Journal Article
Specificity of hammerhead ribozyme cleavage Journal Article
Steric interference modification of the hammerhead ribozyme Journal Article
Structural basis of the enhanced stability of a mutant ribozyme domain and a detailed view of RNA-solvent interactions Journal Article
Structural studies of catalytic RNAs by heteronuclear multi-dimensional NMR. Journal Article
Structural variation induced by different nucleotides at the cleavage site of the hammerhead ribozyme Journal Article
Structure of the Tetrahymena ribozyme:: Base triple sandwich and metal ion at the active site Journal Article
TERTIARY INTERACTIONS WITH THE INTERNAL GUIDE SEQUENCE MEDIATE DOCKING OF THE P1 HELIX INTO THE CATALYTIC CORE OF THE TETRAHYMENA RIBOZYME Journal Article
TERTIARY STRUCTURE AROUND THE GUANOSINE-BINDING SITE OF THE TETRAHYMENA RIBOZYME Journal Article
TETHERING RIBOZYMES TO A RETROVIRAL PACKAGING SIGNAL FOR DESTRUCTION OF VIRAL-RNA Journal Article
THE EFFECT OF BASE MISMATCHES IN THE SUBSTRATE RECOGNITION HELICES OF HAMMERHEAD RIBOZYMES ON BINDING AND CATALYSIS Journal Article
THE EFFICIENCY AND VERSATILITY OF CATALYTIC RNA - IMPLICATIONS FOR AN RNA WORLD Journal Article
THE IMPORTANCE OF BEING RIBOSE AT THE CLEAVAGE SITE IN THE TETRAHYMENA RIBOZYME REACTION Journal Article
THE INTERNAL EQUILIBRIUM OF THE HAMMERHEAD RIBOZYME REACTION Journal Article
THE SELF-SPLICING RNA OF TETRAHYMENA IS TRAPPED IN A LESS ACTIVE CONFORMATION BY GEL PURIFICATION Journal Article
THE TETRAHYMENA RIBOZYME ACTS LIKE AN RNA RESTRICTION ENDONUCLEASE Journal Article
THIOPHOSPHATE INTERFERENCE EXPERIMENTS LOCATE PHOSPHATES IMPORTANT FOR THE HAMMERHEAD RNA SELF-CLEAVAGE REACTION Journal Article
TRANSLOCATION OF AN RNA DUPLEX ON A RIBOZYME Journal Article
The Cech Symposium: A celebration of 25 years of ribozymes, 10 years of TERT, and 60 years of Tom Journal Article
The Noncoding RNA Revolution-Trashing Old Rules to Forge New Ones Journal Article
The Tetrahymena ribozyme cleaves a 5 '-methylene phosphonate monoester similar to 10(2)-fold faster than a normal phosphate diester: Implications for enzyme catalysis of phosphoryl transfer reactions Journal Article
The chemical repertoire of natural ribozymes Journal Article
The global conformation of the hammerhead ribozyme determined using residual dipolar couplings Journal Article
The hammerhead ribozyme Conference Proceeding
The intervening sequence RNA of Tetrahymena is an enzyme. 1986. Journal Article
The parallel universe of RNA folding Journal Article
The structure-function dilemma of the hammerhead ribozyme. Journal Article
Thermodynamic dissection of the substrate-ribozyme interaction in the hammerhead ribozyme Journal Article
Thermodynamics and kinetics for base-pair opening in the P1 duplex of the Tetrahymena group I ribozyme Journal Article
Toward predicting self-splicing and protein-facilitated splicing of group I introns Journal Article
Two major tertiary folding transitions of the Tetrahymena catalytic RNA. Journal Article
Use of intrinsic binding energy for catalysis by an RNA enzyme Journal Article
VISUALIZATION OF A TERTIARY STRUCTURAL DOMAIN OF THE TETRAHYMENA GROUP-I INTRON BY ELECTRON-MICROSCOPY Journal Article
VISUALIZING THE HIGHER-ORDER FOLDING OF A CATALYTIC RNA MOLECULE Journal Article
When to believe what you see. Journal Article
X-ray crystallography of large RNAs: Heavy-atom derivatives by RNA engineering Journal Article

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