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Hoenger, Andreas Professor

Positions

Research Areas research areas

Research

research overview

  • My main research interests are functional and structural analyses by 3-D cryo-electron microscopy of cytoskeletal assemblies and macromolecular structures as well as cellular organelles. We apply cryo-electron tomography to investigate the structure function relationships of large macromolecular assemblies and cellular organelles within their native cytosolic environment. We operate two electron microscopes with the latest data recording systems, and peripheral equipment for specimen preparation and data analysis. I received funding to create a new Cryo-Electron Tomography facility (CU-Boulder Center for Cryo-ET: CCET, total funding about $8M). This will add a new FIBSEM microscope plus various peripheral equipment to the University and to MCD-Biology.

keywords

  • Cellbiology and Cytoskeleton assemblies, 3-D reconstruction of macromolecular assemblies and cellular organelles by cryo-electron microscopy, cryo-electron tomography

Publications

selected publications

Teaching

courses taught

  • MCDB 3501 - Structural Methods for Biological Macromolecules
    Primary Instructor - Fall 2018 / Fall 2019 / Fall 2020 / Spring 2022
    Teaches fundamental knowledge about protein structures, protein interactions and protein folding. Discusses in detail the most common methods on how proteins and macromolecular complexes are studied, such as X-ray crystallography, NMR-spectroscopy and electron microscopy. Offers about 50 percent direct teaching, 40 percent discussion of papers in a journal club style and 10 percent hands-on practicals on software packages relevant to structural biology. Recommended prerequisite: MCDB 2150 or EBIO 2070 (minimum grade C-). Formerly MCDB 4501.
  • MCDB 4100 - Special Topics
    Primary Instructor - Spring 2019
    May be repeated up to 6 total credit hours. Recommended prerequisites: MCDB 3135 and MCDB 3145 (minimum grade C-).
  • MCDB 5210 - Cell Structure and Function (Lecture and Discussion)
    Primary Instructor - Spring 2022
    -
  • MCDB 5230 - Graduate Core 1
    Primary Instructor - Fall 2021
    -

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