Neu, Corey P | CU Experts

Research

research overview

Dr. Neu's research focuses on multiscale biomechanics and mechanobiology of soft tissues, with a special emphasis on connective and cardiac tissues, making use of advanced magnetic resonance imaging and optical/atomic force microscopy-based techniques, to understand development, disease and regeneration in tissues and cells.

keywords

magnetic resonance imaging, biomechanics, imaging, cell and nuclear mechanobiology

Publications

selected publications

chapter
journal article
- Chondrocyte viability is lost during high-rate impact loading by transfer of amplified strain, but not stress, to pericellular and cellular regions. Osteoarthritis and Cartilage. 1822-1830. 2019
- The ecology and evolution of seed predation by Darwin's finches on Tribulus cistoides on the Galapagos Islands. Ecological Monographs. 2019
- Layer-specific arterial micromechanics and microstructure: Influences of age, anatomical location, and processing technique. Journal of Biomechanics. 113-121. 2019
- Deformation Microscopy for Dynamic Intracellular and Intranuclear Mapping of Mechanics with High Spatiotemporal Resolution. Cell Reports. 1607-+. 2019
- Raman spectroscopy-based water content is a negative predictor of articular human cartilage mechanical function. Osteoarthritis and Cartilage. 304-313. 2019
- Cartilage-on-cartilage contact: effect of compressive loading on tissue deformations and structural integrity of bovine articular cartilage. Osteoarthritis and Cartilage. 1699-1709. 2018
- Functional assessment of strains around a full-thickness and critical sized articular cartilage defect under compressive loading using MRI. Osteoarthritis and Cartilage. 1710-1721. 2018
- Annual Education Issue Writing a Review Article for Publication as Part of a Graduate Engineering Course. Journal of Biomechanical Engineering. 2018
- Biomimetic soft fibrous hydrogels for contractile and pharmacologically responsive smooth muscle. Acta Biomaterialia. 121-130. 2018
- Full-volume displacement mapping of anterior cruciate ligament bundles with dualMRI. Extreme Mechanics Letters. 7-14. 2018
- Functional MRI can detect changes in intratissue strains in a full thickness and critical sized ovine cartilage defect model. Journal of Biomechanics. 18-25. 2018
- Indentation mapping revealed poroelastic, but not viscoelastic, properties spanning native zonal articular cartilage. Acta Biomaterialia. 41-49. 2017
- Densification of Type I Collagen Matrices as a Model for Cardiac Fibrosis. Advanced Healthcare Materials. 2017
- In Vivo Multiscale and Spatially-Dependent Biomechanics Reveals Differential Strain Transfer Hierarchy in Skeletal Muscle. ACS Biomaterials Science and Engineering. 2798-2805. 2017
- Cyclic loading of human articular cartilage: The transition from compaction to fatigue. Journal of the Mechanical Behavior of Biomedical Materials. 734-742. 2017
- In Vivo Cellular Infiltration and Remodeling in a Decellularized Ovine Osteochondral Allograft. Tissue Engineering: Parts A, B, and C. 1274-1285. 2016
- Knockdown of the pericellular matrix molecule perlecan lowers in situ cell and matrix stiffness in developing cartilage. Developmental Biology. 242-247. 2016
- Dissociated and Reconstituted Cartilage Microparticles in Densified Collagen Induce Local hMSC Differentiation. Advanced Materials for Optics and Electronics. 5427-5436. 2016
- Mechanisms and Microenvironment Investigation of Cellularized High Density Gradient Collagen Matrices via Densification. Advanced Materials for Optics and Electronics. 2617-2628. 2016
- Mapping the Nonreciprocal Micromechanics of Individual Cells and the Surrounding Matrix Within Living Tissues. Scientific Reports. 2016
- Application of Elastography for the Noninvasive Assessment of Biomechanics in Engineered Biomaterials and Tissues. Annals of Biomedical Engineering. 705-724. 2016
- In vivo articular cartilage deformation: noninvasive quantification of intratissue strain during joint contact in the human knee. Scientific Reports. 2016
- Acellular and cellular high-density, collagen-fibril constructs with suprafibrillar organization. Biomaterials Science. 711-723. 2016
- Synthesis and characterization of a lubricin mimic (mLub) to reduce friction and adhesion on the articular cartilage surface. Biomaterials. 42-50. 2015
- Single cell spectroscopy: Noninvasive measures of small-scale structure and function. Methods. 119-128. 2013

Teaching

courses taught

MCEN 2023 - Statics and Structures
Primary Instructor - Spring 2018 / Spring 2019 / Spring 2020
Covers statics of particles, equivalent force systems, rigid bodies, equilibrium of rigid bodies in two and three dimensions, analysis of truss and frame structures, uniaxially-loaded members, distributed force systems and friction. Degree credit not granted for this course and CVEN 2121 or GEEN 2851.
MCEN 5228 - Special Topics in Mechanical Engineering
Primary Instructor - Fall 2019
Subject matter to be selected from topics of current interest. May be repeated up to 15 credit hours. Same as MCEN 4228.

Background

education and training

Ph.D., University of California-Davis 2004
M.S., Brown University 1999
B.Sc., Brown University 1998

awards and honors

Faculty Early Career Development (CAREER) Program, conferred by National Science Foundation, 2015
Faculty Early Career Development (CAREER) Program, conferred by National Science Foundation, 2014

International Activities

global connections related to teaching and scholarly work (in recent years)

Americas Transnational Region
Asia Continent
Belgium Country
Canada Country
China Country
Ecuador Country
Europe Continent
Ireland Country
Netherlands Country

Other Profiles

CU Experts

Neu, Corey P Donnelly Family Endowed Associate Professor

Positions

Research Areas

Research

research overview

keywords

Publications

selected publications

chapter

journal article

Teaching

courses taught

Background

education and training

awards and honors

International Activities

global connections related to teaching and scholarly work (in recent years)

Other Profiles

ORCID iD

Google Scholar

ResearchGate