Bioorganic and Medicinal Chemistry Letters Journal

Overview

publication venue for

• Extended structure-activity relationship studies of the [1,2,5]oxadiazolo [3,4-b]pyrazine-containing colistin adjuvants 2025
• Structure-activity relationship studies of [1,2,5]oxadiazolo[3,4-b] pyrazine-containing polymyxin-selective resistance-modifying agents 2022
• Oligodeoxynucleotides containing 2 '-amino-LNA nucleotides as constrained morpholino phosphoramidate and phosphorodiamidate monomers 2017
• Discovery and initial structure-activity relationships of N-benzyl tricyclic indolines as antibacterials for methicillin-resistant Staphylococcus aureus 2014
• Highly potent and selective 3-N-methylquinazoline-4(3H)-one based inhibitors of B-Raf^V600E kinase 2014
Fluorogenic assay of alkaline phosphatase activity based on the modulation of excited-state intramolecular proton transfer 2012
New inhibitors of colony spreading in Bacillus subtilis and Bacillus anthracis 2011
Non-oxime pyrazole based inhibitors of B-Raf kinase 2011
The Discovery of furo[2,3-c]pyridine-based indanone oximes as potent and selective B-Raf inhibitors 2011
Application of a novel in silico high-throughput screen to identify selective inhibitors for protein-protein interactions 2010
Syntheses of aminoalcohol-derived macrocycles leading to a small-molecule binder to and inhibitor of Sonic Hedgehog 2009
Quinazolin-2-ylamino-quinazolin-4-ols as novel non-nucleoside inhibitors of bacterial DNA polymerase III 2009
Potent and selective pyrazole-based inhibitors of B-Raf kinase 2008
The chemical and hydroxyl radical scavenging activity changes of ginsenoside-Rb-1 by heat processing 2008
Synthesis, in vitro and in vivo activity of thiamine antagonist transketolase inhibitors 2008
Synthesis of and evaluation of lipid A modification by 4-substituted 4-deoxy arabinose analogs as potential inhibitors of bacterial polymyxin resistance 2008
Non-charged thiamine analogs as inhibitors of enzyme transketolase 2008
Prodrug thiamine analogs as inhibitors of the enzyme transketolase 2008
In vitro selection of phosphorothiolated aptamers 1998
... more

Research

keywords

• 0304 Medicinal and Biomolecular Chemistry, 1115 Pharmacology and Pharmaceutical Sciences, 0305 Organic Chemistry