Potent and selective pyrazole-based inhibitors of B-Raf kinase
Journal Article
Overview
publication date
- August 15, 2008
has subject area
- Animals
- Biochemical Phenomena - Phosphorylation
- Biological Science Disciplines - Chemistry, Pharmaceutical
- Biological Science Disciplines - Drug Design
- Cell Line - Cell Line, Tumor
- Chemistry - Chemistry, Pharmaceutical
- Chemistry - Drug Design
- Crystallography, X-Ray
- Humans
- Investigative Techniques - Drug Design
- Metabolism - Phosphorylation
- Mice
- Models, Chemical
- Neoplasm Transplantation
- Organic Chemistry Phenomena - Phosphorylation
- Peptides - Proto-Oncogene Proteins B-raf
- Peptides - raf Kinases
- Protein Kinase Inhibitors
- Protein-Serine-Threonine Kinases - Proto-Oncogene Proteins B-raf
- Protein-Serine-Threonine Kinases - raf Kinases
- Proteins - Proto-Oncogene Proteins B-raf
- Proteins - raf Kinases
- Proto-Oncogene Proteins - Proto-Oncogene Proteins B-raf
- Proto-Oncogene Proteins - raf Kinases
- Pyrazoles
- Toxicity Tests - Inhibitory Concentration 50
- Toxicological Phenomena - Inhibitory Concentration 50
- Tumor Cells, Cultured - Cell Line, Tumor
has restriction
- closed
Date in CU Experts
- September 3, 2013 2:49 AM
Full Author List
- Hansen JD; Grina J; Newhouse B; Welch M; Topalov G; Littman N; Callejo M; Gloor S; Martinson M; Laird E
author count
- 17
citation count
- 64
published in
Other Profiles
International Standard Serial Number (ISSN)
- 0960-894X
Electronic International Standard Serial Number (EISSN)
- 1464-3405
Digital Object Identifier (DOI)
Additional Document Info
start page
- 4692
end page
- 4695
volume
- 18
issue
- 16