The Discovery of furo[2,3-c]pyridine-based indanone oximes as potent and selective B-Raf inhibitors
Journal Article
Overview
publication date
- February 15, 2011
has subject area
- Animals
- Binding Sites
- Biochemical Phenomena - Structure-Activity Relationship
- Cell Line - Cell Line, Tumor
- Computer Simulation
- Humans
- Hydrocarbons, Aromatic - Indans
- Investigative Techniques - Drug Evaluation, Preclinical
- Investigative Techniques - Drug Evaluation, Preclinical
- Microsomes, Liver
- Models, Chemical
- Models, Molecular
- Oximes
- Peptides - Proto-Oncogene Proteins B-raf
- Pharmacological Phenomena - Structure-Activity Relationship
- Polycyclic Compounds - Indans
- Protein Kinase Inhibitors
- Protein-Serine-Threonine Kinases - Proto-Oncogene Proteins B-raf
- Proteins - Proto-Oncogene Proteins B-raf
- Proto-Oncogene Proteins - Proto-Oncogene Proteins B-raf
- Pyridines
- Rats
- Tumor Cells, Cultured - Cell Line, Tumor
has restriction
- closed
Date in CU Experts
- September 3, 2013 2:49 AM
Full Author List
- Buckmelter AJ; Ren L; Laird ER; Rast B; Miknis G; Wenglowsky S; Schlachter S; Welch M; Tarlton E; Grina J
author count
- 17
citation count
- 23
published in
Other Profiles
International Standard Serial Number (ISSN)
- 0960-894X
Electronic International Standard Serial Number (EISSN)
- 1464-3405
Digital Object Identifier (DOI)
Additional Document Info
start page
- 1248
end page
- 1252
volume
- 21
issue
- 4