subject area of
- A Radical Intermediate in the Conversion of Pentachlorophenol to Tetrachlorohydroquinone by Sphingobium chlorophenolicum Journal Article
- A Small Molecule Inhibitor of Pot1 Binding to Article Telomeric DNA Journal Article
- Activation loop dynamics are controlled by conformation-selective inhibitors of ERK2 Journal Article
- Active-Site Environmental Factors Customize the Photophysics of Photoenzymatic Old Yellow Enzymes Journal Article
- Allosteric Inhibition of PTP1B by a Nonpolar Terpenoid Journal Article
- An E1-E2 fusion protein primes antiviral immune signalling in bacteria Journal Article
- Analysis of neutral mutational drift in an allosteric enzyme Journal Article
- Biophysical Rationale for the Selective Inhibition of PTP1B over TCPTP by Nonpolar Terpenoids Journal Article
- Caspase-Dependent Conversion of Dicer Ribonuclease into a Death-Promoting Deoxyribonuclease Journal Article
- Chiral histidine selection by D-ribose RNA Journal Article
- Comparative Hydrogen-Deuterium Exchange for a Mesophilic vs Thermophilic Dihydrofolate Reductase at 25 degrees C: Identification of a Single Active Site Region with Enhanced Flexibility in the Mesophilic Protein Journal Article
- Correlating Structural and Functional Heterogeneity of Immobilized Enzymes Journal Article
- Crystal Structure of CRN-4: Implications for Domain Function in Apoptotic DNA Degradation Journal Article
- Crystal structure of HsIUV complexed with a vinyl sulfone inhibitor: Corroboration of a proposed mechanism of allosteric activation of HsIV by HsIU Journal Article
- Differential Effects of a Mutation on the Normal and Promiscuous Activities of Orthologs: Implications for Natural and Directed Evolution Journal Article
- Discriminating between HuR and TTP binding sites using the k-spectrum kernel method Journal Article
- Dual mechanisms specify Doa4-mediated deubiquitination at multivesicular bodies Journal Article
- Dynamic equilibria in protein kinases Journal Article
- Effects of Acyclovir, Foscarnet, and Ribonucleotides on Herpes Simplex Virus-1 DNA Polymerase: Mechanistic Insights and a Novel Mechanism for Preventing Stable Incorporation of Ribonucleotides into DNA Journal Article
- Enhanced product stability in the hammerhead ribozyme. Journal Article
- Essential functions of amino-terminal domains in the yeast telomerase catalytic subunit revealed by selection for viable mutants Journal Article
- Evolutionarily Conserved Allosteric Communication in Protein Tyrosine Phosphatases Journal Article
- Hammerhead redux: does the new structure fit the old biochemical data? Journal Article
- Herpes Simplex Virus-1 Helicase-Primase: Roles of Each Subunit in DNA Binding and Phosphodiester Bond Formation Journal Article
- Histone Parylation factor 1 contributes to the inhibition of PARP1 by cancer drugs Journal Article
- Human DNA polymerase alpha uses a combination of positive and negative selectivity to polymerize purine dNTPs with high fidelity Journal Article
- Hydrogen deuterium exchange defines catalytically linked regions of protein flexibility in the catechol O-methyltransferase reaction Journal Article
- Inactivation of the uptake hydrogenase in the purple non-sulfur photosynthetic bacterium Rubrivivax gelatinosus CBS enables a biological water-gas shift platform for H-2 production Journal Article
- Microbially Guided Discovery and Biosynthesis of Biologically Active Natural Products Journal Article
- Mutation in TERT separates processivity from anchor-site function Journal Article
- Order, dynamics and metal-binding in the lead-dependent ribozyme Journal Article
- PKA catalytic subunit compartmentation regulates contractile and hypertrophic responses to beta-adrenergic signaling Journal Article
- Phylogenetic-comparative analysis of the eukaryal ribonuclease P RNA Journal Article
- Polymerase and Exonuclease Activities in Herpes Simplex Virus Type 1 DNA Polymerase Are Not Highly Coordinated Journal Article
- Rapid and Simple Ribozymic Aminoacylation Using Three Conserved Nucleotides Journal Article
- Redox Regulation of SH2-Domain-Containing Protein Tyrosine Phosphatases by Two Backdoor Cysteines Journal Article
- Structural Basis for Substrate Specificity in ArnB. A Key Enzyme in the Polymyxin Resistance Pathway of Gram-Negative Bacteria Journal Article
- Structure and kinetics of indole-3-glycerol phosphate synthase from Pseudomonas aeruginosa: Decarboxylation is not essential for indole formation Journal Article
- Structure of Est3 reveals a bimodal surface with differential roles in telomere replication Journal Article
- Structure of Mediator of RhoA-Dependent Invasion (MRDI) Explains Its Dual Function as a Metabolic Enzyme and a Mediator of Cell Invasion Journal Article
- Structure of the Human cGAS-DNA Complex Reveals Enhanced Control of Immune Surveillance Journal Article
- Structure-Based Assignment of Ile, Leu, and Val Methyl Groups in the Active and Inactive Forms of the Mitogen-Activated Protein Kinase Extracellular Signal-Regulated Kinase Journal Article
- Substitution of distal and active site residues reduces product inhibition of E1 from Acidothermus Cellulolyticus Journal Article
- TATA-binding Protein and Transcription Factor IIB Induce Transcript Slipping during Early Transcription by RNA Polymerase II Journal Article
- Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells Journal Article
- The Non-Coding B2 RNA Binds to the DNA Cleft and Active-Site Region of RNA Polymerase II Journal Article
- The carboxy-terminal domain of the DExD/H protein YxiN is sufficient to confer specificity for 23 S rRNA Journal Article
- The global conformation of the hammerhead ribozyme determined using residual dipolar couplings Journal Article
- The hexameric eukaryotic MCM helicase: Building symmetry from nonidentical parts Journal Article
- Translocation after synthesis of a four-nucleotide RNA commits RNA polymerase II to promoter escape Journal Article
- Two-step Ligand Binding in a (βα)8 Barrel Enzyme SUBSTRATE-BOUND STRUCTURES SHED NEW LIGHT ON THE CATALYTIC CYCLE OF HisA Journal Article
- Understanding histone acetyltransferase Rtt109 structure and function: how many chaperones does it take? Journal Article
- p38β Mitogen-Activated Protein Kinase Modulates Its Own Basal Activity by Autophosphorylation of the Activating Residue Thr180 and the Inhibitory Residues Thr241 and Ser261 Journal Article