Rifampin inhibits Toll-like receptor 4 signaling by targeting myeloid differentiation protein 2 and attenuates neuropathic pain
Journal Article
Overview
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Animals
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Animals, Newborn
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Antigens, Surface - Lymphocyte Antigen 96
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Biochemical Phenomena - Protein Binding
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Biochemical Phenomena - Signal Transduction
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Biological Factors - Interleukin-1beta
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Biological Factors - Interleukin-1beta
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Biological Factors - Tumor Necrosis Factor-alpha
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Biological Factors - Tumor Necrosis Factor-alpha
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Blood Proteins - Tumor Necrosis Factor-alpha
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Carrier Proteins - Lymphocyte Antigen 96
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Cell Line
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Cell Line, Transformed - HEK293 Cells
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Cell Physiological Phenomena - Signal Transduction
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Cells - Macrophages
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Cells - Microglia
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Cells, Cultured
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Chemistry Techniques, Analytical - Blotting, Western
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Connective Tissue Cells - Macrophages
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DNA-Binding Proteins - NF-kappa B
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Electrochemical Techniques - Blotting, Western
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Epithelial Cells - HEK293 Cells
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Heterocyclic Compounds, 4 or More Rings - Rifampin
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Humans
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Immune System - Macrophages
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Immunologic Techniques - Blotting, Western
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Inorganic Chemicals - Nitric Oxide
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Macrocyclic Compounds - Rifampin
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Male
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Metabolism - Protein Binding
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Mice
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Molecular Probe Techniques - Blotting, Western
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Molecular Probe Techniques - Blotting, Western
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Mononuclear Phagocyte System - Macrophages
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Multiprotein Complexes - NF-kappa B
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Myeloid Cells - Macrophages
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Nervous System - Microglia
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Nervous System Diseases - Hyperalgesia
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Nitrogen Compounds - Nitric Oxide
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Nitrogen Compounds - Nitric Oxide
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Nuclear Proteins - NF-kappa B
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Oxygen Compounds - Nitric Oxide
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Peptides - Interleukin-1beta
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Peptides - Interleukin-1beta
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Peptides - Tumor Necrosis Factor-alpha
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Peptides - Tumor Necrosis Factor-alpha
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Peripheral Nervous System Diseases - Neuralgia
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Pharmacological Phenomena - Dose-Response Relationship, Drug
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Proteins - Interleukin-1beta
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Proteins - Interleukin-1beta
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Proteins - Tumor Necrosis Factor-alpha
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Proteins - Tumor Necrosis Factor-alpha
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Proteins - Tumor Necrosis Factor-alpha
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Rats
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Rats, Sprague-Dawley
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Signs and Symptoms - Hyperalgesia
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Signs and Symptoms - Neuralgia
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Toll-Like Receptor 4
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Toxicological Phenomena - Dose-Response Relationship, Drug
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Transcription Factors - NF-kappa B
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Date in CU Experts
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September 6, 2013 5:12 AM
Full Author List
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Wang X; Grace PM; Pham MN; Cheng K; Strand KA; Smith C; Li J; Watkins LR; Yin H
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