subject area of
- 3 ' terminal diversity of MRP RNA and other human noncoding RNAs revealed by deep sequencing Journal Article
- piggyBac as a high-capacity transgenesis and gene-therapy vector in human cells and mice Journal Article
- A glycan shield on chimpanzee CD4 protects against infection by primate lentiviruses (HIV/SIV) Journal Article
- A multicolor riboswitch-based platform for imaging of RNA in live mammalian cells Journal Article
- A myosin-7B-dependent endocytosis pathway mediates cellular entry of alpha-synuclein fibrils and polycation-bearing cargos Journal Article
- A putative N-terminal nuclear export sequence is sufficient for Mps1 nuclear exclusion during interphase Journal Article
- An Essential Role of Variant Histone H3.3 for Ectomesenchyme Potential of the Cranial Neural Crest Journal Article
- Bacterial cGAS-like enzymes synthesize diverse nucleotide signals Journal Article
- Bacterial peptidoglycan muropeptides benefit mitochondrial homeostasis and animal physiology by acting as ATP synthase agonists Journal Article
- CST does not evict elongating telomerase but prevents initiation by ssDNA binding Journal Article
- Cadherin cis and trans interactions are mutually cooperative Journal Article
- Cadherin clusters stabilized by a combination of specific and nonspecific cis-interactions Journal Article
- Cell-Type-Specific Chromatin States Differentially Prime Squamous Cell Carcinoma Tumor-Initiating Cells for Epithelial to Mesenchymal Transition Journal Article
- Centriole and Golgi microtubule nucleation are dispensable for the migration of human neutrophil-like cells Journal Article
- Changes to the TDP-43 and FUS Interactomes Induced by DNA Damage Journal Article
- Characterization of Single-Cell Osmotic Swelling Dynamics for New Physical Biomarkers Journal Article
- Computational and Functional Analysis of the Virus-Receptor Interface Reveals Host Range Trade-Offs in New World Arenaviruses Journal Article
- Contributions of the TEL-patch Amino Acid Cluster on TPP1 to Telomeric DNA Synthesis by Human Telomerase Journal Article
- Cyclophilins Facilitate Dissociation of the Human Papillomavirus Type 16 Capsid Protein L1 from the L2/DNA Complex following Virus Entry Journal Article
- Delta Np63 alpha represses anti-proliferative genes via H2A.Z deposition Journal Article
- Downregulation of MicroRNA miR-526a by Enterovirus Inhibits RIG-I-Dependent Innate Immune Response Journal Article
- ERK phosphorylation of MED14 in promoter complexes during mitogen-induced gene activation by Elk-1 Journal Article
- Epicardial YAP/TAZ orchestrate an immunosuppressive response following myocardial infarction Journal Article
- Estrogen receptor profiling and activity in cardiac myocytes Journal Article
- FASTKD1 and FASTKD4 have opposite effects on expression of specific mitochondrial RNAs, depending upon their endonuclease-like RAP domain Journal Article
- FUS binds the CTD of RNA polymerase II and regulates its phosphorylation at Ser2 Journal Article
- Glucuronic acid and the ethanol metabolite ethyl-glucuronide cause toll-like receptor 4 activation and enhanced pain Journal Article
- HMGB1 Activates Proinflammatory Signaling via TLR5 Leading to Allodynia Journal Article
- Heterochromatin anomalies and double-stranded RNA accumulation underlie C9orf72 poly(PR) toxicity Journal Article
- Human Pumilio Proteins Recruit Multiple Deadenylases to Efficiently Repress Messenger RNAs Journal Article
- Identification of human TERT elements necessary for telomerase recruitment to telomeres Journal Article
- Impact of human D398N single nucleotide polymorphism on intracellular calcium response mediated by alpha 3 beta 4 alpha 5 nicotinic acetylcholine receptors Journal Article
- Intrinsically active variants of Erk oncogenically transform cells and disclose unexpected autophosphorylation capability that is independent of TEY phosphorylation Journal Article
- Intrinsically disordered RGG/RG domains mediate degenerate specificity in RNA binding Journal Article
- Inventory of telomerase components in human cells reveals multiple subpopulations of hTR and hTERT Journal Article
- Ire1-mediated decay in mammalian cells relies on mRNA sequence, structure, and translational status Journal Article
- Largazole and Its Derivatives Selectively Inhibit Ubiquitin Activating Enzyme (E1) Journal Article
- Live-cell imaging reveals the dynamics of PRC2 and recruitment to chromatin by SUZ12-associated subunits Journal Article
- Loss of MeCP2 in adult 5-HT neurons induces 5-HT1A autoreceptors, with opposite sex-dependent anxiety and depression phenotypes Journal Article
- Microbial Siderophore Enterobactin Promotes Mitochondrial Iron Uptake and Development of the Host via Interaction with ATP Synthase Journal Article
- Microbially Guided Discovery and Biosynthesis of Biologically Active Natural Products Journal Article
- Molecular consequences of the R453C hypertrophic cardiomyopathy mutation on human β-cardiac myosin motor function Journal Article
- Morphine activates neuroinflammation in a manner parallel to endotoxin Journal Article
- Multiplexable, locus-specific targeting of long RNAs with CRISPR-Display Journal Article
- Nascent transcript analysis of glucocorticoid crosstalk with TNF defines primary and cooperative inflammatory repression Journal Article
- Nitric oxide produced by cytochrome c oxidase helps stabilize HIF-1 alpha in hypoxic mammalian cells Journal Article
- Nuclear TRIM25 Specifically Targets Influenza Virus Ribonucleoproteins to Block the Onset of RNA Chain Elongation Journal Article
- Nuclear compartmentalization of TERT mRNA and TUG1 lncRNA is driven by intron retention Journal Article
- Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains Journal Article
- Nudt21 Controls Cell Fate by Connecting Alternative Polyadenylation to Chromatin Signaling Journal Article
- Optically Diffracting Hydrogels for Screening Kinase Activity in Vitro and in Cell Lysate: Impact of Material and Solution Properties Journal Article
- Owl monkey CCR5 reveals synergism between CD4 and CCR5 in HIV-1 entry Journal Article
- Oxidative stress induces mitotic arrest by inhibiting Aurora A-involved mitotic spindle formation Journal Article
- PINK1 Triggers Autocatalytic Activation of Parkin to Specify Cell Fate Decisions Journal Article
- Paired heavy- and light-chain signatures contribute to potent SARS-CoV-2 neutralization in public antibody responses Journal Article
- Phosphorylation regulates human OCT4 Journal Article
- Programmable Extracellular Vesicles for Macromolecule Delivery and Genome Modifications Journal Article
- Programming human pluripotent stem cells into white and brown adipocytes Journal Article
- Promotion of vesicular zinc efflux by ZIP13 and its implications for spondylocheiro dysplastic Ehlers-Danlos syndrome Journal Article
- RABIF/MSS4 is a Rab-stabilizing holdase chaperone required for GLUT4 exocytosis Journal Article
- RNA Duplex Map in Living Cells Reveals Higher-Order Transcriptome Structure Journal Article
- RNA Seeds Higher-Order Assembly of FUS Protein Journal Article
- RNA sensor LGP2 inhibits TRAF ubiquitin ligase to negatively regulate innate immune signaling Journal Article
- RNase L Reprograms Translation by Widespread mRNA Turnover Escaped by Antiviral mRNAs Journal Article
- RNase L promotes the formation of unique ribonucleoprotein granules distinct from stress granules Journal Article
- Rare missense variants in CHRNB4 are associated with reduced risk of nicotine dependence Journal Article
- Rifampin inhibits Toll-like receptor 4 signaling by targeting myeloid differentiation protein 2 and attenuates neuropathic pain Journal Article
- SARS-CoV-2 spike S1 subunit induces neuroinflammatory, microglial and behavioral sickness responses: Evidence of PAMP-like properties Journal Article
- Select steroid hormone glucuronide metabolites can cause toll-like receptor 4 activation and enhanced pain Journal Article
- Selective use of primate CD4 receptors by HIV-1 Journal Article
- Single-cell imaging reveals unexpected heterogeneity of telomerase reverse transcriptase expression across human cancer cell lines Journal Article
- Sorafenib targets the mitochondrial electron transport chain complexes and ATP synthase to activate the PINK1-Parkin pathway and modulate cellular drug response Journal Article
- Structure and Function of Steroid Receptor RNA Activator Protein, the Proposed Partner of SRA Noncoding RNA Journal Article
- Synthetic chimeric nucleases function for efficient genome editing Journal Article
- TRIM28 regulates RNA polymerase II promoter-proximal pausing and pause release Journal Article
- TRIM5α Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation Journal Article
- Targeting of Polycomb Repressive Complex 2 to RNA by Short Repeats of Consecutive Guanines Journal Article
- Tau aggregates are RNA-protein assemblies that mislocalize multiple nuclear speckle components Journal Article
- The DEK oncoprotein is a Su(var) that is essential to heterochromatin integrity Journal Article
- The Herpes Simplex Virus 1 Protein ICP4 Acts as both an Activator and a Repressor of Host Genome Transcription during Infection Journal Article
- The Role of PIEZO2 in Human Mechanosensation Journal Article
- The SCF-Fbw7 ubiquitin ligase degrades MED13 and MED13L and regulates CDK8 module association with Mediator Journal Article
- The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity Journal Article
- The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair Journal Article
- The p38β Mitogen-activated Protein Kinase Possesses an Intrinsic Autophosphorylation Activity, Generated by a Short Region Composed of the α-G Helix and MAPK Insert Journal Article
- The structure of human CST reveals a decameric assembly bound to telomeric DNA Journal Article
- The β3 subunit of the nicotinic acetylcholine receptor: Modulation of gene expression and nicotine consumption Journal Article
- Toward a Consensus on the Binding Specificity and Promiscuity of PRC2 for RNA Journal Article
- Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains Journal Article
- UV inactivation of sewage isolated human adenovirus Journal Article
- Variants of the yeast MAPK Mpk1 are fully functional independently of activation loop phosphorylation Journal Article
- XPO5 promotes primary miRNA processing independently of RanGTP Journal Article
- p38β Mitogen-Activated Protein Kinase Modulates Its Own Basal Activity by Autophosphorylation of the Activating Residue Thr180 and the Inhibitory Residues Thr241 and Ser261 Journal Article