Single-cell pharmacokinetic imaging reveals a therapeutic strategy to overcome drug resistance to the microtubule inhibitor eribulin
Journal Article
Overview
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Animals
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Antineoplastic Agents
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Biological Science Disciplines - Chemistry, Pharmaceutical
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Carrier Proteins - ATP Binding Cassette Transporter, Subfamily B
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Carrier Proteins - ATP Binding Cassette Transporter, Subfamily B
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Cell Line
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Cell Survival
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Chemistry - Chemistry, Pharmaceutical
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Diagnostic Imaging - Microscopy, Confocal
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Diagnostic Imaging - Microscopy, Fluorescence
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Drug Delivery Systems - Drug Carriers
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Drug Resistance, Neoplasm
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Female
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Furans
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Gene Transfer Techniques - Transfection
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Heterocyclic Compounds, 2-Ring - Benzopyrans
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Humans
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Investigative Techniques - Microscopy, Confocal
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Investigative Techniques - Microscopy, Fluorescence
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Investigative Techniques - Xenograft Model Antitumor Assays
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Isoquinolines
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Ketones
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Membrane Proteins - ATP Binding Cassette Transporter, Subfamily B
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Membrane Proteins - ATP Binding Cassette Transporter, Subfamily B
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Membrane Proteins - ATP Binding Cassette Transporter, Subfamily B
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Mice, Nude
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Nanoparticles
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Neoplasm Transplantation - Xenograft Model Antitumor Assays
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Neoplasms
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Pharmaceutical Preparations - Drug Carriers
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Pharmacological Phenomena - Dose-Response Relationship, Drug
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Proteins - ATP Binding Cassette Transporter, Subfamily B
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Pyrans - Benzopyrans
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Recombinant Fusion Proteins
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Recombination, Genetic - Transfection
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Tetrazoles
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Toxicological Phenomena - Dose-Response Relationship, Drug
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Tubulin Modulators
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Date in CU Experts
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November 10, 2014 11:58 AM
Full Author List
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Laughney AM; Kim E; Sprachman MM; Miller MA; Kohler RH; Yang KS; Orth JD; Mitchison TJ; Weissleder R
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