Dr. Batey's research focuses on the structure-function relationships of RNA. The model system that his research group utilizes is the riboswitch, an element found in messenger RNAs that can specifically bind a small molecule to direct gene expression in a cis-fashion. To understand how these genetic regulatory elements work, several aspects of their function are studied using x-ray crystallography to develop three-dimensional models of these RNAs and their complexes with small molecules and a set of biophysical, biochemical and molecular biological and genetic tools to relate ligand binding to gene regulation. A second area of research is understanding the structural and functional relationship to the transcriptome. This work focuses upon the transcription factor Sox2 and its ability to interact with dsRNA. Our current research is focused on two key questions: (1) how does RNA binding govern Sox2's biological activity and (2) do other related proteins have RNA-mediated activities.
CHEM 8991 - Doctoral Dissertation
All doctoral students must register for 30 hours of dissertation credit as part of the requirements for the degree. For a detailed discussion of doctoral dissertation credit, refer to the Graduate School section. (Spring 2019 UC Boulder)
MCDB 6000 - Introduction to Laboratory Methods
Introduces methodology and techniques used in biological research. Designed as a tutorial between a few students and one faculty member. Students are expected to read original research papers, discuss findings, and to plan and execute experiments in selected areas. Open only to MCDB graduate students. May be repeated up to 9 total credit hours. (Spring 2019 UC Boulder)
MCDB 8990 - Doctoral Dissertation
All doctoral students must register for not fewer than 30 hours of dissertation credit as part of the requirements for the degree. For a detailed discussion of doctoral dissertation credit, refer to the Graduate School section. (Spring 2019 UC Boulder)
CHEM 4700 - Foundations of Biochemistry
Covers chemistry of aqueous solutions; energetics in biology; structure of proteins, nucleic acids, carbohydrates, and membranes; protein evolution; macromolecular interactions; enzyme kinetics, mechanism and regulation. Will be taught from a strong chemical perspective and mastery of basic concepts of organic and physical chemistry will be required. Formerly CHEM 4700. Same as BCHM 5700. (Fall 2018 UC Boulder)
CHEM 5700 - Foundations of Biochemistry
Covers chemistry of aqueous solutions; energetics in biology; structure of proteins, nucleic acids, carbohydrates, and membranes; protein evolution; macromolecular interactions; enzyme kinetics, mechanism and regulation. Will be taught from a strong chemical perspective and mastery of basic concepts of organic and physical chemistry will be required. Formerly CHEM 5700. Same as BCHM 4700. (Fall 2018 UC Boulder)
CHEM 8991 - Doctoral Dissertation
All doctoral students must register for 30 hours of dissertation credit as part of the requirements for the degree. For a detailed discussion of doctoral dissertation credit, refer to the Graduate School section. (Fall 2018 UC Boulder)
MCDB 8990 - Doctoral Dissertation
All doctoral students must register for not fewer than 30 hours of dissertation credit as part of the requirements for the degree. For a detailed discussion of doctoral dissertation credit, refer to the Graduate School section. (Fall 2018 UC Boulder)
CHEM 8991 - Doctoral Dissertation
All doctoral students must register for 30 hours of dissertation credit as part of the requirements for the degree. For a detailed discussion of doctoral dissertation credit, refer to the Graduate School section. (Summer 2018 UC Boulder)
CHEM 8991 - Doctoral Dissertation
All doctoral students must register for 30 hours of dissertation credit as part of the requirements for the degree. For a detailed discussion of doctoral dissertation credit, refer to the Graduate School section. (Spring 2018 UC Boulder)
MCDB 6000 - Introduction to Laboratory Methods
Introduces methodology and techniques used in biological research. Designed as a tutorial between a few students and one faculty member. Students are expected to read original research papers, discuss findings, and to plan and execute experiments in selected areas. Open only to MCDB graduate students. May be repeated up to 9 total credit hours. (Spring 2018 UC Boulder)
MCDB 8990 - Doctoral Dissertation
All doctoral students must register for not fewer than 30 hours of dissertation credit as part of the requirements for the degree. For a detailed discussion of doctoral dissertation credit, refer to the Graduate School section. (Spring 2018 UC Boulder)
