• Contact Info
Publications in VIVO
 

Garcea, Robert L, M.D. Professor

Positions

Research Areas research areas

Research

research overview

  • My laboratory studies the structure and assembly of small DNA viruses. Specifically we are addressing three fundamental control points : 1) how is capsid assembly prevented in the cytoplasm, 2) how do the capsid proteins identify their genome for encapsidation, and 3) are specific nuclear sites used as 'workbenches' to couple viral DNA replication with capsid assembly. Our study of human papillomavirus assembly has been translated into the development of vaccine reagents for the prevention of cervical cancer. We are also developing new methods of vaccine storage and administration in order to generate thermostable, single-shot formulation of several antigens suitable for use in resource-poor areas of the world.

keywords

  • structure and assembly of small DNA viruses with a focus on polyoma and papillomaviruses, development of low cost HPV vaccines for underdeveloped countries, new methods of vaccine delivery

Publications

selected publications

Teaching

courses taught

  • MCDB 4750 Animal Virology (Spring 2019)
  • MCDB 4840 Upper-Division Independent Study (Spring 2019)
  • MCDB 4990 Honors Thesis (Spring 2019)
  • MCDB 5750 Animal Virology (Spring 2019)
  • MCDB 6000 Introduction to Laboratory Methods (Spring 2019)
  • MCDB 8990 Doctoral Dissertation (Spring 2019)
  • CHEM 6901 Research in Chemistry (Fall 2018)
  • MCDB 4980 Honors Research (Fall 2018)
  • MCDB 6000 Introduction to Laboratory Methods (Fall 2018)
  • MCDB 8990 Doctoral Dissertation (Fall 2018)
  • MCDB 4750 Animal Virology (Spring 2018)
  • MCDB 4840 Upper-Division Independent Study (Spring 2018)
  • MCDB 4990 Honors Thesis (Spring 2018)
  • MCDB 5750 Animal Virology (Spring 2018)
  • MCDB 6000 Introduction to Laboratory Methods (Spring 2018)
  • MCDB 8990 Doctoral Dissertation (Spring 2018)

Background

International Activities

global connections related to teaching and scholarly work (in recent years)

Other Profiles