Gelation of a Monoclonal Antibody at the Silicone Oil-Water Interface and Subsequent Rupture of the Interfacial Gel Results in Aggregation and Particle Formation
Journal Article
Overview
publication date
- April 1, 2015
has subject area
- Alkalies - Water
- Anions - Water
- Biochemical Phenomena - Protein Denaturation
- Biological Science Disciplines - Chemistry, Pharmaceutical
- Biomedical and Dental Materials - Polysorbates
- Biomedical and Dental Materials - Silicone Oils
- Biophysical Phenomena - Protein Denaturation
- Blood Proteins - Antibodies, Monoclonal
- Chemistry - Chemistry, Pharmaceutical
- Chromatography, Gel
- Complex Mixtures - Gels
- Drug Stability
- Elasticity
- Ethylene Glycols - Polysorbates
- Globulins - Antibodies, Monoclonal
- Immunoproteins - Antibodies, Monoclonal
- Investigative Techniques - Rheology
- Investigative Techniques - Technology, Pharmaceutical
- Macromolecular Substances - Polysorbates
- Macromolecular Substances - Silicone Oils
- Manufactured Materials - Polysorbates
- Manufactured Materials - Silicone Oils
- Organosilicon Compounds - Silicone Oils
- Oxygen Compounds - Water
- Pharmaceutical Preparations - Gels
- Physics - Rheology
- Protein Aggregates
- Protein Conformation
- Protein Stability
- Surface-Active Agents
- Technology - Technology, Pharmaceutical
- Viscosity
has restriction
- closed
Date in CU Experts
- May 6, 2015 7:23 AM
Full Author List
- Mehta SB; Lewus R; Bee JS; Randolph TW; Carpenter JF
author count
- 5
citation count
- 65
published in
Other Profiles
International Standard Serial Number (ISSN)
- 0022-3549
Electronic International Standard Serial Number (EISSN)
- 1520-6017
Digital Object Identifier (DOI)
Additional Document Info
start page
- 1282
end page
- 1290
volume
- 104
issue
- 4