subject area of
- 3-DIMENSIONAL MODEL OF THE ACTIVE-SITE OF THE SELF-SPLICING RIBOSOMAL-RNA PRECURSOR OF TETRAHYMENA Journal Article
- 5' EXON REQUIREMENT FOR SELF-SPLICING OF THE TETRAHYMENA-THERMOPHILA PRE-RIBOSOMAL RNA AND IDENTIFICATION OF A CRYPTIC 5' SPLICE SITE IN THE 3' EXON Journal Article
- In Crystallo Selection to Establish New RNA Crystal Contacts Journal Article
- A CONSERVED BASE PAIR WITHIN HELIX-P4 OF THE TETRAHYMENA RIBOZYME HELPS TO FORM THE TERTIARY STRUCTURE REQUIRED FOR SELF-SPLICING Journal Article
- A HAMMERHEAD RIBOZYME ALLOWS SYNTHESIS OF A NEW FORM OF THE TETRAHYMENA RIBOZYME HOMOGENEOUS IN LENGTH WITH A 3' END BLOCKED FOR TRANSESTERIFICATION Journal Article
- A LABILE PHOSPHODIESTER BOND AT THE LIGATION JUNCTION IN A CIRCULAR INTERVENING SEQUENCE RNA Journal Article
- A MODEL FOR THE RNA-CATALYZED REPLICATION OF RNA Journal Article
- A SELF-SPLICING GROUP-I INTRON IN THE NUCLEAR PRE-RIBOSOMAL-RNA OF THE GREEN-ALGA, ANKISTRODESMUS-STIPITATUS Journal Article
- A TETRAHYMENA INTRON NUCLEOTIDE CONNECTED TO THE GTP ARGININE SITE Journal Article
- ALTERATION OF SUBSTRATE-SPECIFICITY FOR THE ENDORIBONUCLEOLYTIC CLEAVAGE OF RNA BY THE TETRAHYMENA RIBOZYME Journal Article
- ALTERNATIVE SECONDARY STRUCTURES IN THE 5' EXON AFFECT BOTH FORWARD AND REVERSE SELF-SPLICING OF THE TETRAHYMENA INTERVENING SEQUENCE RNA Journal Article
- AMINOACYL ESTERASE-ACTIVITY OF THE TETRAHYMENA RIBOZYME Journal Article
- AN ULTRAVIOLET-INDUCIBLE ADENOSINE ADENOSINE CROSS-LINK REFLECTS THE CATALYTIC STRUCTURE OF THE TETRAHYMENA RIBOZYME Journal Article
- AUTOCATALYTIC CYCLIZATION OF AN EXCISED INTERVENING SEQUENCE RNA IS A CLEAVAGE LIGATION REACTION Journal Article
- An early transition state for folding of the P4-P6 RNA domain Journal Article
- BIOLOGICAL CATALYSIS BY RNA Journal Article
- Beginning to understand the end of the chromosome Journal Article
- CATALYSIS OF RNA CLEAVAGE BY A RIBOZYME DERIVED FROM THE GROUP-I INTRON OF ANABAENA PRE-TRNA(LEU) Journal Article
- CATALYSIS OF RNA CLEAVAGE BY THE TETRAHYMENA-THERMOPHILA RIBOZYME .1. KINETIC DESCRIPTION OF THE REACTION OF AN RNA SUBSTRATE COMPLEMENTARY TO THE ACTIVE-SITE Journal Article
- CATALYSIS OF RNA CLEAVAGE BY THE TETRAHYMENA-THERMOPHILA RIBOZYME .2. KINETIC DESCRIPTION OF THE REACTION OF AN RNA SUBSTRATE THAT FORMS A MISMATCH AT THE ACTIVE-SITE Journal Article
- CATALYTIC RNA - STRUCTURE AND MECHANISM Journal Article
- CHROMATIN STRUCTURE AT THE REPLICATION ORIGINS AND TRANSCRIPTION-INITIATION REGIONS OF THE RIBOSOMAL-RNA GENES OF TETRAHYMENA Journal Article
- CHROMATIN STRUCTURE OF THE RIBOSOMAL-RNA GENES OF TETRAHYMENA-THERMOPHILA AS ANALYZED BY TRIMETHYLPSORALEN CROSSLINKING INVIVO Journal Article
- COAXIALLY STACKED RNA HELICES IN THE CATALYTIC CENTER OF THE TETRAHYMENA RIBOZYME Journal Article
- COUPLING OF TETRAHYMENA RIBOSOMAL-RNA SPLICING TO BETA-GALACTOSIDASE EXPRESSION IN ESCHERICHIA-COLI Journal Article
- Comparison of crystal structure interactions and thermodynamics for stabilizing mutations in the Tetrahymena ribozyme Journal Article
- Conserved thermochemistry of guanosine nucleophile binding for structurally distinct group I ribozymes Journal Article
- Crystals by design: A strategy for crystallization of a ribozyme derived from the Tetrahymena group I intron Journal Article
- DEFINING THE INSIDE AND OUTSIDE OF A CATALYTIC RNA MOLECULE Journal Article
- DELETION OF NONCONSERVED HELICES NEAR THE 3' END OF THE RIBOSOMAL-RNA INTRON OF TETRAHYMENA-THERMOPHILA ALTERS SELF-SPLICING BUT NOT CORE CATALYTIC ACTIVITY Journal Article
- DETERMINANTS OF THE 3' SPLICE SITE FOR SELF-SPLICING OF THE TETRAHYMENA PRE-RRNA Journal Article
- DIFFERENT NUCLEOSOME SPACING IN TRANSCRIBED AND NON-TRANSCRIBED REGIONS OF THE RIBOSOMAL-RNA GENE IN TETRAHYMENA-THERMOPHILA Journal Article
- DIRECT MEASUREMENT OF OLIGONUCLEOTIDE SUBSTRATE BINDING TO WILD-TYPE AND MUTANT RIBOZYMES FROM TETRAHYMENA Journal Article
- DNA BIOCHEMISTRY - G-STRINGS AT CHROMOSOME ENDS Journal Article
- DNA CLEAVAGE CATALYZED BY THE RIBOZYME FROM TETRAHYMENA Journal Article
- Energetics and cooperativity of tertiary hydrogen bonds in RNA structure Journal Article
- Engineering cis-telomerase RNAs that add telomeric repeats to themselves Journal Article
- Evolution of Tetrahymena ribozyme mutants with increased structural stability Journal Article
- Exocyclic amine of the conserved G center dot U pair at the cleavage site of the Tetrahymena ribozyme contributes to 5'-splice site selection and transition state stabilization Journal Article
- FATE OF AN INTERVENING SEQUENCE RIBONUCLEIC-ACID - EXCISION AND CYCLIZATION OF THE TETRAHYMENA RIBOSOMAL RIBONUCLEIC-ACID INTERVENING SEQUENCE INVIVO Journal Article
- GUANOSINE BINDING REQUIRED FOR CYCLIZATION OF THE SELF-SPLICING INTERVENING SEQUENCE RIBONUCLEIC-ACID FROM TETRAHYMENA-THERMOPHILA Journal Article
- IDENTIFICATION OF RIBOZYMES WITHIN A RIBOZYME LIBRARY THAT EFFICIENTLY CLEAVE A LONG SUBSTRATE RNA Journal Article
- INTERMOLECULAR EXON LIGATION OF THE RIBOSOMAL-RNA PRECURSOR OF TETRAHYMENA - OLIGONUCLEOTIDES CAN FUNCTION AS 5' EXONS Journal Article
- INVITRO SPLICING OF THE RIBOSOMAL-RNA PRECURSOR IN NUCLEI OF TETRAHYMENA Journal Article
- Joining the two domains of a group I ribozyme to form the catalytic core Journal Article
- Kinetic pathway for folding of the Tetrahymena ribozyme revealed by three UV-inducible crosslinks Journal Article
- LOCALIZATION OF TRANSCRIBED REGIONS ON EXTRACHROMOSOMAL RIBOSOMAL-RNA GENES OF TETRAHYMENA-THERMOPHILA BY R-LOOP MAPPING Journal Article
- MECHANISM OF RECOGNITION OF THE 5' SPLICE SITE IN SELF-SPLICING GROUP-I INTRONS Journal Article
- METAL-ION CATALYSIS IN THE TETRAHYMENA RIBOZYME REACTION Journal Article
- METAL-ION REQUIREMENTS FOR SEQUENCE-SPECIFIC ENDORIBONUCLEASE ACTIVITY OF THE TETRAHYMENA RIBOZYME Journal Article
- MINOR-GROOVE RECOGNITION OF THE CONSERVED G-CENTER-DOT-U PAIR AT THE TETRAHYMENA RIBOZYME REACTION SITE Journal Article
- MITOCHONDRIAL TELOMERES - SURPRISING DIVERSITY OF REPEATED TELOMERIC DNA-SEQUENCES AMONG 6 SPECIES OF TETRAHYMENA Journal Article
- MONO-VALENT CATION INDUCED STRUCTURE OF TELOMERIC DNA - THE G-QUARTET MODEL Journal Article
- MOVEMENT OF THE GUIDE SEQUENCE DURING RNA CATALYSIS BY A GROUP-I RIBOZYME Journal Article
- MUTATIONS IN A NONCONSERVED SEQUENCE OF THE TETRAHYMENA RIBOZYME INCREASE ACTIVITY AND SPECIFICITY Journal Article
- Multiple folding pathways for the P4-P6 RNA domain Journal Article
- Mutagenesis and comparative sequence analysis of a base triple joining the two domains of group I ribozymes Journal Article
- NEW REACTIONS OF THE RIBOSOMAL-RNA PRECURSOR OF TETRAHYMENA AND THE MECHANISM OF SELF-SPLICING Journal Article
- OLIGOMERIZATION OF INTERVENING SEQUENCE RNA MOLECULES IN THE ABSENCE OF PROTEINS Journal Article
- ONE BINDING-SITE DETERMINES SEQUENCE SPECIFICITY OF TETRAHYMENA PRE-RIBOSOMAL-RNA SELF-SPLICING, TRANSSPLICING, AND RNA ENZYME-ACTIVITY Journal Article
- PHYLOGENETIC-RELATIONSHIPS AND ALTERED GENOME STRUCTURES AMONG TETRAHYMENA MITOCHONDRIAL DNAS Journal Article
- Quantifying the energetic interplay of RNA tertiary and secondary structure interactions Journal Article
- REACTIONS OF THE INTERVENING SEQUENCE OF THE TETRAHYMENA RIBOSOMAL RIBONUCLEIC-ACID PRECURSOR - PH-DEPENDENCE OF CYCLIZATION AND SITE-SPECIFIC HYDROLYSIS Journal Article
- RELATIVE ORIENTATION OF RNA HELICES IN A GROUP-I RIBOZYME DETERMINED BY HELIX EXTENSION ELECTRON-MICROSCOPY Journal Article
- REPLACEMENT OF THE CONSERVED G-CENTER-DOT-U WITH A G-C PAIR AT THE CLEAVAGE SITE OF THE TETRAHYMENA RIBOZYME DECREASES BINDING, REACTIVITY, AND FIDELITY Journal Article
- REPLICATION OF THE EXTRACHROMOSOMAL RIBOSOMAL-RNA GENES OF TETRAHYMENA-THERMOPHILIA Journal Article
- REPRESENTATION OF THE SECONDARY AND TERTIARY STRUCTURE OF GROUP-I INTRONS Journal Article
- REVERSE SELF-SPLICING OF THE TETRAHYMENA GROUP-I INTRON - IMPLICATION FOR THE DIRECTIONALITY OF SPLICING AND FOR INTRON TRANSPOSITION Journal Article
- REVERSIBILITY OF CYCLIZATION OF THE TETRAHYMENA RIBOSOMAL-RNA INTERVENING SEQUENCE - IMPLICATION FOR THE MECHANISM OF SPLICE SITE CHOICE Journal Article
- RIBOZYME INHIBITORS - DEOXYGUANOSINE AND DIDEOXYGUANOSINE ARE COMPETITIVE INHIBITORS OF SELF-SPLICING OF THE TETRAHYMENA RIBOSOMAL RIBONUCLEIC-ACID PRECURSOR Journal Article
- RIBOZYME RECOGNITION OF RNA BY TERTIARY INTERACTIONS WITH SPECIFIC RIBOSE 2'-OH GROUPS Journal Article
- RIBOZYME-CATALYZED AND NONENZYMATIC REACTIONS OF PHOSPHATE DIESTERS - RATE EFFECTS UPON SUBSTITUTION OF SULFUR FOR A NONBRIDGING PHOSPHORYL OXYGEN ATOM Journal Article
- RNA AS AN ENZYME Journal Article
- RNA AS AN ENZYME Journal Article
- RNA AS AN RNA-POLYMERASE - NET ELONGATION OF AN RNA PRIMER CATALYZED BY THE TETRAHYMENA RIBOZYME Journal Article
- RNA CHEMISTRY - RIBOZYME SELF-REPLICATION Journal Article
- RNA SPLICING - 3 THEMES WITH VARIATIONS Journal Article
- RNA tertiary folding monitored by fluorescence of covalently attached pyrene Journal Article
- ROLE OF CONSERVED SEQUENCE ELEMENT-9L AND ELEMENT-2 IN SELF-SPLICING OF THE TETRAHYMENA RIBOSOMAL-RNA PRECURSOR Journal Article
- SECONDARY STRUCTURE OF THE CIRCULAR FORM OF THE TETRAHYMENA RIBOSOMAL-RNA INTERVENING SEQUENCE - A TECHNIQUE FOR RNA STRUCTURE-ANALYSIS USING CHEMICAL PROBES AND REVERSE-TRANSCRIPTASE Journal Article
- SECONDARY STRUCTURE OF THE TETRAHYMENA RIBOSOMAL-RNA INTERVENING SEQUENCE - STRUCTURAL HOMOLOGY WITH FUNGAL MITOCHONDRIAL INTERVENING SEQUENCES Journal Article
- SELECTION OF CIRCULARIZATION SITES IN A GROUP-1 IVS RNA REQUIRES MULTIPLE ALIGNMENTS OF AN INTERNAL TEMPLATE-LIKE SEQUENCE Journal Article
- SELF-ASSEMBLY OF A GROUP-I INTRON ACTIVE-SITE FROM ITS COMPONENT TERTIARY STRUCTURAL DOMAINS Journal Article
- SELF-CATALYZED CYCLIZATION OF THE INTERVENING SEQUENCE RNA OF TETRAHYMENA - INHIBITION BY INTERCALATING DYES Journal Article
- SELF-CATALYZED CYCLIZATION OF THE INTERVENING SEQUENCE RNA OF TETRAHYMENA - INHIBITION BY METHIDIUMPROPYL.EDTA AND LOCALIZATION OF THE MAJOR DYE BINDING-SITES Journal Article
- SELF-SPLICING AND ENZYMATIC CLEAVAGE OF RNA BY A GROUP-I INTERVENING SEQUENCE Journal Article
- SELF-SPLICING AND ENZYMATIC-ACTIVITY OF AN INTERVENING SEQUENCE RNA FROM TETRAHYMENA Journal Article
- SELF-SPLICING RNA - AUTO-EXCISION AND AUTO-CYCLIZATION OF THE RIBOSOMAL-RNA INTERVENING SEQUENCE OF TETRAHYMENA Journal Article
- SELF-SPLICING RNA - IMPLICATIONS FOR EVOLUTION Journal Article
- SELF-SPLICING RNA AND AN RNA ENZYME IN TETRAHYMENA Journal Article
- SEQUENCE REQUIREMENTS FOR SELF-SPLICING OF THE TETRAHYMENA-THERMOPHILA PRE-RIBOSOMAL RNA Journal Article
- SEQUENCE-SPECIFIC ENDORIBONUCLEASE ACTIVITY OF THE TETRAHYMENA RIBOZYME - ENHANCED CLEAVAGE OF CERTAIN OLIGONUCLEOTIDE SUBSTRATES THAT FORM MISMATCHED RIBOZYME SUBSTRATE COMPLEXES Journal Article
- SITES OF CIRCULARIZATION OF THE TETRAHYMENA RIBOSOMAL-RNA IVS ARE DETERMINED BY SEQUENCE AND INFLUENCED BY POSITION AND SECONDARY STRUCTURE Journal Article
- SPECIFIC INTERACTION BETWEEN THE SELF-SPLICING RNA OF TETRAHYMENA AND ITS GUANOSINE SUBSTRATE - IMPLICATIONS FOR BIOLOGICAL CATALYSIS BY RNA Journal Article
- SPECIFICITY FOR 3',5'-LINKED SUBSTRATES IN RNA-CATALYZED RNA POLYMERIZATION Journal Article
- STEREOCHEMISTRY OF RNA CLEAVAGE BY THE TETRAHYMENA RIBOZYME AND EVIDENCE THAT THE CHEMICAL STEP IS NOT RATE-LIMITING Journal Article
- STRUCTURAL CONVENTIONS FOR GROUP-I INTRONS Journal Article
- STRUCTURES INVOLVED IN TETRAHYMENA RIBOSOMAL-RNA SELF-SPLICING AND RNA ENZYME-ACTIVITY Journal Article
- Self-splicing and enzymatic activity of an intervening sequence RNA from Tetrahymena Journal Article
- Self-splicing of group I introns. Journal Article
- Self-splicing of the Tetrahymena intron from mRNA in mammalian cells Journal Article
- Structural basis of the enhanced stability of a mutant ribozyme domain and a detailed view of RNA-solvent interactions Journal Article
- Structure of the Tetrahymena ribozyme:: Base triple sandwich and metal ion at the active site Journal Article
- TELOMERIC REPEATS OF TETRAHYMENA-MALACCENSIS MITOCHONDRIAL-DNA - A MULTIMODAL DISTRIBUTION THAT FLUCTUATES ERRATICALLY DURING GROWTH Journal Article
- TERTIARY STRUCTURE AROUND THE GUANOSINE-BINDING SITE OF THE TETRAHYMENA RIBOZYME Journal Article
- THE CHEMISTRY OF SELF-SPLICING RNA AND RNA ENZYMES Journal Article
- THE CONSERVED U.G PAIR IN THE 5' SPLICE SITE DUPLEX OF A GROUP-I INTRON IS REQUIRED IN THE 1ST BUT NOT THE 2ND STEP OF SELF-SPLICING Journal Article
- THE EFFICIENCY AND VERSATILITY OF CATALYTIC RNA - IMPLICATIONS FOR AN RNA WORLD Journal Article
- THE INTERVENING SEQUENCE EXCISED FROM THE RIBOSOMAL-RNA PRECURSOR OF TETRAHYMENA CONTAINS A 5'-TERMINAL GUANOSINE RESIDUE NOT ENCODED BY THE DNA Journal Article
- THE INTERVENING SEQUENCE OF THE RIBOSOMAL-RNA PRECURSOR IS CONVERTED TO A CIRCULAR RNA IN ISOLATED-NUCLEI OF TETRAHYMENA Journal Article
- THE INTERVENING SEQUENCE RNA OF TETRAHYMENA IS AN ENZYME Journal Article
- THE SELF-SPLICING RNA OF TETRAHYMENA IS TRAPPED IN A LESS ACTIVE CONFORMATION BY GEL PURIFICATION Journal Article
- THE TELOMERES OF THE LINEAR MITOCHONDRIAL-DNA OF TETRAHYMENA THERMOPHILA CONSIST OF 53-BP TANDEM REPEATS Journal Article
- THE TETRAHYMENA INTERVENING SEQUENCE RIBONUCLEIC-ACID ENZYME IS A PHOSPHOTRANSFERASE AND AN ACID-PHOSPHATASE Journal Article
- THE TETRAHYMENA RIBOZYME ACTS LIKE AN RNA RESTRICTION ENDONUCLEASE Journal Article
- TRANSCRIBED AND NON-TRANSCRIBED REGIONS OF TETRAHYMENA RIBOSOMAL GENE CHROMATIN HAVE DIFFERENT ACCESSIBILITIES TO MICROCOCCAL NUCLEASE Journal Article
- TRANSLOCATION OF AN RNA DUPLEX ON A RIBOZYME Journal Article
- Tetrahymena telomerase is active as a monomer Journal Article
- The Euplotes La motif protein p43 has properties of a telomerase-specific subunit Journal Article
- The intervening sequence RNA of Tetrahymena is an enzyme. 1986. Journal Article
- The parallel universe of RNA folding Journal Article
- Thermodynamic stability of the P4-P6 domain RNA tertiary structure measured by temperature gradient gel electrophoresis Journal Article
- Thermodynamics and kinetics for base-pair opening in the P1 duplex of the Tetrahymena group I ribozyme Journal Article
- Two major tertiary folding transitions of the Tetrahymena catalytic RNA. Journal Article
- VISUALIZING THE HIGHER-ORDER FOLDING OF A CATALYTIC RNA MOLECULE Journal Article
- X-ray crystallography of large RNAs: Heavy-atom derivatives by RNA engineering Journal Article