Enzyme Inhibitors
PubMed MeSh Term
Overview
subject area of
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A Selective Inhibitor and Probe of the Cellular Functions of Jumonji C Domain-Containing Histone Demethylases Journal Article
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Activation of FAK and Src are receptor-proximal events required for netrin signaling Journal Article
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Allosteric Inhibition of PTP1B by a Nonpolar Terpenoid Journal Article
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An initial investigation of spinal mechanisms underlying pain enhancement induced by fractalkine, a neuronally released chemokine Journal Article
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Analysis of Three Architectures for Controlling PTP1B with Light Journal Article
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Atypical protein kinase Cs are the Ras effectors that mediate repression of myogenic satellite cell differentiation Journal Article
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Axial Stretch of Rat Single Ventricular Cardiomyocytes Causes an Acute and Transient Increase in Ca2+ Spark Rate Journal Article
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B6D2F1 Mice Are a Suitable Model of Oxidative Stress-Mediated Impaired Endothelium-Dependent Dilation With Aging Journal Article
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Bacterial peptidoglycan muropeptides benefit mitochondrial homeostasis and animal physiology by acting as ATP synthase agonists Journal Article
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Biophysical Rationale for the Selective Inhibition of PTP1B over TCPTP by Nonpolar Terpenoids Journal Article
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Calcineurin activity is required for cardiac remodelling in pregnancy Journal Article
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Cell biology - Lessons in rational drug design for protein kinases Journal Article
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Cytochrome P-450 2C9 signaling does not contribute to age-associated vascular endothelial dysfunction in humans Journal Article
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Delta-6-desaturase Links Polyunsaturated Fatty Acid Metabolism With Phospholipid Remodeling and Disease Progression in Heart Failure Journal Article
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Development of Substrate-Selective Probes for Affinity Pulldown of Histone Demethylases Journal Article
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Discovery of novel inhibitors for human intestinal maltase: virtual screening in a WISDOM environment and in vitro evaluation Journal Article
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ERK1/2 activation is a therapeutic target in age-related macular degeneration Journal Article
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ERK1/2 is required for myoblast proliferation but is dispensable for muscle gene expression and cell fusion Journal Article
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Effects of dopamine β-hydroxylase genotype and disulfiram inhibition on catecholamine homeostasis in mice Journal Article
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Endothelial Progenitor Cell Function, Apoptosis, and Telomere Length in Overweight/Obese Humans Journal Article
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Endothelial nitric oxide synthase inhibition does not alter endothelial progenitor cell colony forming capacity or migratory activity Journal Article
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Evidence that Mitotic Exit Is a Better Cancer Therapeutic Target Than Spindle Assembly Journal Article
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Fragile X mental retardation protein regulates heterosynaptic plasticity in the hippocampus. Journal Article
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Functional characterization of mouse α4β2 nicotinic acetylcholine receptors stably expressed in HEK293T cells Journal Article
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Global regulation of post-translational modifications on core histones Journal Article
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INFLUENCE OF ENDURANCE TRAINING ON THE AGE-RELATED DECLINE IN HEPATIC GLYCONEOGENESIS Journal Article
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INHIBITION OF THE HAMMERHEAD RIBOZYME BY NEOMYCIN Journal Article
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Identification and Mechanistic Studies of a Novel Ubiquitin E1 Inhibitor Journal Article
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Identification of novel MAP kinase pathway signaling targets by functional proteomics and mass spectrometry Journal Article
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Impaired endothelium-dependent vasodilation in overweight and obese adult humans is not limited to muscarinic receptor agonists Journal Article
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Impaired escape performance and enhanced conditioned fear in rats following exposure to an uncontrollable stressor are mediated by glutamate and nitric oxide in the dorsal raphe nucleus Journal Article
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In vivo induction of membrane damage by beta-amyloid peptide oligomers Journal Article
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Inhibiting PKMζ reveals dorsal lateral and dorsal medial striatum store the different memories needed to support adaptive behavior Journal Article
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Inhibition of mitogen-activated kinase signaling sensitizes HeLa cells to Fas receptor-mediated apoptosis Journal Article
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Insufficient sleep is associated with impaired nitric oxide-mediated endothelium-dependent vasodilation Journal Article
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Intracellular calcium and myosin isoform transitions - Calcineurin and calcium-calmodulin kinase pathways regulate preferential activation of the iia myosin heavy chain promoter Journal Article
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Involvement of spinal cord nuclear factor κB activation in rat models of proinflammatory cytokine-mediated pain facilitation Journal Article
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Isolation of long-lived mutants in Caenorhabditis elegans using selection for resistance to juglone Journal Article
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Mechanism of Competitive Inhibition and Destabilization of Acidothermus cellulolyticus Endoglucanase 1 by Ionic Liquids Journal Article
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Microbially Guided Discovery and Biosynthesis of Biologically Active Natural Products Journal Article
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Mitogen-activated protein kinases (Erk1,2) phosphorylate Lys-Ser-Pro (KSP) repeats in neurofilament proteins NF-H and NF-M Journal Article
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Mitotic phosphorylation of Golgi reassembly stacking protein 55 by mitogen-activated protein kinase ERK2 Journal Article
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Neonatal infection-induced memory impairment after lipopolysaccharide in adulthood is prevented via caspase-1 inhibition Journal Article
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Nitric Oxide-Mediated Endothlium-Dependent Vasodilation Is Impaired with Borderline High-LDL Cholesterol Journal Article
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Non-charged thiamine analogs as inhibitors of enzyme transketolase Journal Article
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Non-oxime pyrazole based inhibitors of B-Raf kinase Journal Article
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Novel Scaffolds of Cell-Active Histone Demethylase Inhibitors Identified from High-Throughput Screening Journal Article
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Oncogenes and tumor angiogenesis:: Differential modes of vascular endothelial growth factor up-regulation in ras-transformed epithelial cells and fibroblasts Journal Article
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PKC-permitted elevation of sarcolemmal K-ATP concentration may explain female-specific resistance to myocardial infarction Journal Article
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Parallel Multiplicative Target Screening against Divergent Bacterial Replicases: Identification of Specific Inhibitors with Broad Spectrum Potential Journal Article
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Pharmacologic inhibitors of MKK1 and MKK2 Journal Article
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Phosphatase inhibition leads to histone deacetylases 1 and 2 phosphorylation and disruption of corepressor interactions Journal Article
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Prodrug thiamine analogs as inhibitors of the enzyme transketolase Journal Article
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Prostaglandins are necessary and sufficient to induce contextual fear learning impairments after interleukin-1 beta injections into the dorsal hippocampus Journal Article
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Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor Journal Article
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Quantitative Analysis of Histone Demethylase Probes Using Fluorescence Polarization Journal Article
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Quinazolin-2-ylamino-quinazolin-4-ols as novel non-nucleoside inhibitors of bacterial DNA polymerase III Journal Article
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RNA aptamers to the peptidyl transferase inhibitor chloramphenicol Journal Article
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Rapid induction of apoptosis during Kinesin-5 inhibitor-induced mitotic arrest in HL60 cells Journal Article
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Rational Design of Novel Allosteric EYA2 Inhibitors as Potential Therapeutics for Multiple Brain Cancers. Journal Article
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Removal of FKBP12 enhances mTOR-Raptor interactions, LTP, memory, and perseverative/repetitive behavior. Journal Article
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Role of the cAMP signaling pathway in the regulation of gonadotropin-releasing hormone secretion in GT1 cells Journal Article
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Role of the loop containing residue 115 in the induced-fit mechanism of the bacterial cell wall biosynthetic enzyme MurA Journal Article
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Small molecule telomerase inhibitors are also potent inhibitors of telomeric C-strand synthesis. Journal Article
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Snake venom phospholipase A2s (Asp49 and Lys49) induce mechanical allodynia upon peri-sciatic administration: involvement of spinal cord glia, proinflammatory cytokines and nitric oxide Journal Article
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Social approach, anxiety, and altered tryptophan hydroxylase 2 activity in juvenile BALB/c and C57BL/6J mice Journal Article
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Spinal glia and proinflammatory cytokines mediate mirror-image neuropathic pain in rats Journal Article
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Stress-induced changes in blood leukocyte distribution - Role of adrenal steroid hormones Journal Article
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Switching human telomerase on and off with hPOT1 protein in vitro Journal Article
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Synthesis, in vitro and in vivo activity of thiamine antagonist transketolase inhibitors Journal Article
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The AP-3 complex: a coat of many colours Journal Article
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The essential and multifunctional TFIIH complex Journal Article
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The kinase suppressor of Ras (KSR) modulates growth factor and Ras signaling by uncoupling Elk-1 phosphorylation from MAP kinase activation Journal Article
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The role of calcium-independent phospholipase A2 in cardiolipin remodeling in the spontaneously hypertensive heart failure rat heart Journal Article
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Thiolutin is a zinc chelator that inhibits the Rpn11 and other JAMM metalloproteases Journal Article
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Traumatic brain injury-induced neuronal damage in the somatosensory cortex causes formation of rod-shaped microglia that promote astrogliosis and persistent neuroinflammation Journal Article
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Xanthine oxidase does not contribute to impaired peripheral conduit artery endothelium-dependent dilatation with ageing Journal Article
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