research overview
- Dr. Bryant's research focuses on designing 3D biomaterials, which she employs 3D models to answer fundamental biological questions and designs 3D cell scaffolds to guide tissue growth and integration for regenerative medicine. In particular, her laboratory has a keen interest in understanding mechanotransduction pathways in cells and understanding the importance of loading in tissue regeneration for cartilage, bone, tendon, and cardiovascular tissues. Her laboratory has also been very interested in uncovering the mechanisms of how the body responds to implanted biomaterials and using this knowledge to develop novel strategies that promote healing and facilitate integration of the engineered tissue into the host tissue, supporting long-term function. Through careful control over the 3D environment, particularly in the presence of physiological cues, her lab hopes to better understand cellular processes towards translating her materials-based technologies in vivo and improving functional tissue regeneration and integration.