publication venue for

• Single-molecule Microscopy Reveals That TFIIE Subunits Dynamically Interact With Preinitiation Complexes in a Manner Impacted by TFIIH 2025
• The RNA-binding Selectivity of the RGG/ RG Motifs of hnRNP U is Abolished by Elements Within the C-terminal Intrinsically Disordered Region 2024
• GMMA Can Stabilize Proteins Across Different Functional Constraints 2024
• Activation Loop Plasticity and Active Site Coupling in the MAP Kinase, ERK2 2023
• Context-dependence of T-loop Mediated Long-range RNA Tertiary Interactions 2023
• Regulation of Gene Expression Through Effector-dependent Conformational Switching by Cobalamin Riboswitches 2022
• Spn1 and Its Dynamic Interactions with Spt6, Histones and Nucleosomes 2022
• Merging Established Mechanisms with New Insights: Condensates, Hubs, and the Regulation of RNA Polymerase II Transcription 2022
• Two Classes of Myosin Inhibitors, Para-nitroblebbistatin and Mavacamten, Stabilize β-Cardiac Myosin in Different Structural and Functional States 2021
• RNA Polymerase II Transcription 2021
• The Role of XPB/Ssl2 dsDNA Translocase Processivity in Transcription Start-site Scanning 2021
• Archaea: The Final Frontier of Chromatin 2021
• Release of Human TFIIB from Actively Transcribing Complexes Is Triggered upon Synthesis of 7-and 9-nt RNAs 2020
• Multiple Modes of Protein-Protein Interactions Promote RNP Granule Assembly 2018
• Transcription Factor Mediator Interfaces: Multiple and Multi-Valent 2017
• The HMGB1 C-Terminal Tail Regulates DNA Bending 2016
• Macromolecular Complexes in Transcription and Co-Transcriptional RNA Processing 2016
• Noncoding RNAs: Regulators of the Mammalian Transcription Machinery 2016
• A Highly Coupled Network of Tertiary Interactions in the SAM-I Riboswitch and Their Role in Regulatory Tuning 2015
• Contributions of the TEL-patch Amino Acid Cluster on TPP1 to Telomeric DNA Synthesis by Human Telomerase 2015
• Dynamic and Thermodynamic Response of the Ras Protein Cdc42Hs upon Association with the Effector Domain of PAK3 2014
• Extracellular-Regulated Kinase 2 Is Activated by the Enhancement of Hinge Flexibility 2014
• Structure and Function of Steroid Receptor RNA Activator Protein, the Proposed Partner of SRA Noncoding RNA 2014
• Multiple C-Terminal Tails within a Single E. coli SSB Homotetramer Coordinate DNA Replication and Repair 2013
• Structural Insights into Transcriptional Repression by Noncoding RNAs That Bind to Human Pol II 2013
• The Non-Coding B2 RNA Binds to the DNA Cleft and Active-Site Region of RNA Polymerase II 2013
• Molecular Mechanism of Membrane Binding of the GRP1 PH Domain 2013
• Nucleotides Adjacent to the Ligand-Binding Pocket are Linked to Activity Tuning in the Purine Riboswitch 2013
• Insights into the Regulatory Landscape of the Lysine Riboswitch 2012
• Life's Simple Measures: Unlocking the Proteome 2012
• Activator-Mediator Binding Stabilizes RNA Polymerase II Orientation within the Human Mediator-RNA Polymerase II-TFIIF Assembly 2012
• Effects of Pathogenic Proline Mutations on Myosin Assembly 2012
• Community-Wide Assessment of Protein-Interface Modeling Suggests Improvements to Design Methodology 2011
• The Rate of Polymerase Release upon Filling the Gap between Okazaki Fragments Is Inadequate to Support Cycling during Lagging Strand Synthesis 2011
• Hotspot-Centric De Novo Design of Protein Binders 2011
• Polymerase Chaperoning and Multiple ATPase Sites Enable the E. coli DNA Polymerase III Holoenzyme to Rapidly Form Initiation Complexes 2011
• Structure of the BamC Two-Domain Protein Obtained by Rosetta with a Limited NMR Data Set 2011
• Multiple POT1-TPP1 Proteins Coat and Compact Long Telomeric Single-Stranded DNA 2011
• Crystal Structure of BamD: An Essential Component of the β-Barrel Assembly Machinery of Gram-Negative Bacteria 2011
• The Transcription Factor Spn1 Regulates Gene Expression via a Highly Conserved Novel Structural Motif 2010
• Membrane Docking Geometry and Target Lipid Stoichiometry of Membrane-Bound PKCα C2 Domain: A Combined Molecular Dynamics and Experimental Study 2010
• RNA Polymerase II and TAFs Undergo a Slow Isomerization after the Polymerase Is Recruited to Promoter-Bound TFIID 2010
• Discrimination between Closely Related Cellular Metabolites by the SAM-I Riboswitch 2010
• Structural and Biophysical Studies of Human PARP-1 in Complex with Damaged DNA 2010
• Lattice Structure of Cytoplasmic Microtubules in a Cultured Mammalian Cell 2009
• Insights into the Dynamics of Specific Telomeric Single-Stranded DNA Recognition by Pot1pN 2009
• Understanding the sequence specificity of tRNA binding to elongation factor Tu using tRNA mutagenesis. 2009
• A Structural Basis for the Recognition of 2′-Deoxyguanosine by the Purine Riboswitch 2009
• Hydrogen-exchange mass spectrometry reveals activation-induced changes in the conformational mobility of p38 alpha MAP kinase 2008
• A beta-hairpin comprising the nuclear localization sequence sustains the self-associated states of nucleosome assembly protein 1. 2008
• TFIIA changes the conformation of the DNA in TBP/TATA complexes and increases their kinetic stability 2007
• Directed mutagenesis identifies amino acid residues involved in elongation factor Tu binding to yeast Phe-tRNAPhe. 2007
• HURP wraps microtubule ends with an additional tubulin sheet that has a novel conformation of tubulin 2007
• Thermodynamic and kinetic characterization of ligand binding to the purine riboswitch aptamer domain (vol 359, pg 754, 2006) 2006
• Nucleosome core particles containing a poly(dA center dot dT) sequence element exhibit a locally distorted DNA structure 2006
• A new model for Schizosaccharomyces pombe telomere recognition: The telomeric single-stranded DNA-binding activity of Pot1(1-389) 2006
• Thermodynamic and kinetic characterization of ligand binding to the purine riboswitch aptamer domain 2006
• The crystal structure of GCAP3 suggests molecular mechanism of GCAP-linked cone dystrophies 2006
• Alanine scanning of MS2 coat protein reveals protein-phosphate contacts involved in thermodynamic hot spots. 2006
• The solvation interface is a determining factor in peptide conformational preferences 2006
• Quantitative analysis of deoxynucleotide substitutions in the codon-anticodon helix. 2006
• Divergent evolution within protein superfolds inferred from profile-based phylogenetics 2005
• Hydrogen exchange solvent protection by an ATP analogue reveals conformational changes in ERK2 upon activation 2005
• A three-dimensional cryo-electron microscopy structure of the bacteriophage φKZ head 2005
• A bipartite polymerase-processivity factor interaction: only the internal beta binding site of the alpha subunit is required for processive replication by the DNA polymerase III holoenzyme. 2005
• Caveolin-1 interacts directly with dynamin-2 2005
• Crystal Structures of Human DcpS in Ligand-free and m7GDP-bound forms Suggest a Dynamic Mechanism for Scavenger mRNA Decapping 2005
• Nucleosomes in solution exist as a mixture of twist-defect states 2005
• Defined structural changes occur in a nucleosome upon Amt1 transcription factor binding 2004
• Mcm10 and Cdc45 cooperate in origin activation in Saccharomyces cerevisiae 2004
• Mcm10 and Cdc45 Cooperate in Origin Activation in Saccharomyces cerevisiae 2004
• Surface-decoration of microtubules by human Tau 2004
• The 12 Å structure of trypsin-treated measles virus N-RNA 2004
• Structural basis for telomeric single-stranded DNA recognition by yeast Cdc13 2004
• Kinetic analysis of site-specific photoaptamer-protein cross-linking 2004
• Structural distortion of p53 by the mutation R249S and its rescue by a designed peptide: Implications for "Mutant conformation" 2004
• Complex formation with kinesin motor domains affects the structure of microtubules 2004
• A structural analysis of the interaction between ncd tail and tubulin protofilaments 2003
• Towards an understanding of the poliovirus replication complex: The solution structure of the soluble domain of the poliovirus 3A protein 2003
• Quantitative analysis of aspartate receptor signaling complex reveals that the homogeneous two-state model is inadequate: Development of a heterogeneous two-state model 2003
• Refined solution structure of the iron-responsive element RNA using residual dipolar couplings 2003
• Crystal structures of nucleosome core particles in complex with minor groove DNA-binding ligands 2003
• Functional analysis of the glutathione S-transferase 3 from Onchocerca volvulus (Ov-GST-3): A parasite GST confers increased resistance to oxidative stress in Caenorhabditis elegans 2003
• Simulation of folding of a small alpha-helical protein in atomistic detail using worldwide-distributed computing (vol 323, pg 927, 2002) 2002
• The carboxy-terminal domain of the DExD/H protein YxiN is sufficient to confer specificity for 23 S rRNA 2002
• Simulation of folding of a small alpha-helical protein in atomistic detail using worldwide-distributed computing 2002
• Native-like mean structure in the unfolded ensemble of small proteins 2002
• Blocking transcription through a nucleosome with synthetic DNA ligands 2002
• Solvent mediated interactions in the structure of the nucleosome core particle at 1.9 Å resolution 2002
• Crystal structure of HsIUV complexed with a vinyl sulfone inhibitor: Corroboration of a proposed mechanism of allosteric activation of HsIV by HsIU 2002
• The HIV plus-strand transfer reaction: determination of replication-competent intermediates and identification of a novel lentiviral element, the primer over-extension sequence. 2002
• Kinetic and mechanistic analysis of the RNA polymerase II transcription reaction at the human interleukin-2 promoter 2001
• Kinetic and mechanistic analysis of the RNA polymerase II transcrption reaction at the human interleukin-2 promoter. 2001
• Modifying the specificity of an RNA backbone contact 2001
• Sequence-specific recognition of DNA in the nucleosome by pyrrole-imidazole polyamides 2001
• Identification of thermodynamically relevant interactions between EF-Tu and backbone elements of tRNA 2001
• Structural and energetic analysis of RNA recognition by a universally conserved protein from the signal recognition particle 2001
• Polymerization, three-dimensional structure and mechanical properties of Dictyostelium versus rabbit muscle actin filaments 2000
• A new look at the microtubule binding patterns of dimeric kinesins 2000
• Comparative sequence analysis of the complete human sarcomeric myosin heavy chain family: Implications for functional diversity 1999
• Nicotinic acetylcholine receptor at 4.6 Å resolution: Transverse tunnels in the channel wall 1999
• Identification of the acidic residues in the active site of DNA polymerase III. 1999
• NMR solution structure of the lead-dependent ribozyme: Evidence for dynamics in RNA catalysis 1998
• Order, dynamics and metal-binding in the lead-dependent ribozyme 1998
• The effects of salt on the TATA binding protein-DNA interaction from a hyperthermophilic archaeon 1998
• An atomic model of crystalline actin tubes: Combining electron microscopy with X-ray crystallography 1998
• The mouse mammary tumour virus promoter positioned on a tetramer of histones H3 and H4 binds nuclear factor 1 and OTF1 1998
• The mathematics of SELEX against complex targets 1998
• Structure and dynamics of the iron responsive element RNA: Implications for binding of the RNA by iron regulatory binding proteins 1997
• Solution structure of the first three zinc fingers of TFIIIA bound to the cognate DNA sequence: determinants of affinity and sequence specificity. 1997
• Characterization of nucleosome core particles containing histone proteins made in bacteria 1997
• A DNA polymerase III holoenzyme-like subassembly from an extreme thermophilic eubacterium. 1997
• Crystals by design: A strategy for crystallization of a ribozyme derived from the Tetrahymena group I intron 1997
• A 29 residue region of the sarcomeric myosin rod is necessary for filament formation 1997
• Motor domains of kinesin and ncd interact with microtubule protofilaments with the same binding geometry 1997
• A network of heterogeneous hydrogen bonds in GNRA tetraloops 1996
• The crystal structure of a hyperthermophilic archaeal TATA-box binding protein 1996
• Bent pseudoknots and novel RNA inhibitors of type 1 human immunodeficiency virus (HIV-1) reverse transcriptase 1996
• Polarity of 2-D and 3-D maps of tubulin sheets and motor-decorated sheets 1996
• Interaction of the Bacillus stearothermophilus ribosomal protein S15 with 16 S rRNA .1. Defining the minimal RNA site 1996
• Interaction of the Bacillus stearothermophilus ribosomal protein S15 with 16 S rRNA .2. Specificity determinants of RNA-protein recognition 1996
• In vitro evolution of the DNA binding sites of Escherichia coli methionine repressor, MetJ 1996
• IN-VITRO SELECTION OF SMALL RNAS THAT BIND TO ESCHERICHIA-COLI PHENYLALANYL-TRANSFER-RNA SYNTHETASE 1994
• GAAA TETRALOOP AND CONSERVED BULGE STABILIZE TERTIARY STRUCTURE OF A GROUP-I INTRON DOMAIN 1994
• VISUALIZATION OF A TERTIARY STRUCTURAL DOMAIN OF THE TETRAHYMENA GROUP-I INTRON BY ELECTRON-MICROSCOPY 1994
• TRANSLATION INITIATION COMPLEX-FORMATION WITH 30-S RIBOSOMAL PARTICLES MUTATED AT CONSERVED POSITIONS IN THE 3'-MINOR DOMAIN OF 16-S RNA 1993
• THE ORIENTATION OF PORIN OMPF IN THE OUTER-MEMBRANE OF ESCHERICHIA-COLI 1993
• AN EFFICIENT PROCEDURE FOR ASSIGNMENT OF THE PROTON, CARBON AND NITROGEN RESONANCES IN C-13/N-15 LABELED NUCLEIC-ACIDS 1993
• 2-DIMENSIONAL CRYSTALLIZATION OF THE LIGHT-HARVESTING COMPLEX FROM RHODOSPIRILLUM-RUBRUM 1993
• ASSEMBLY OF THE BACTERIOPHAGE-T4 REPLICATION MACHINE REQUIRES THE ACIDIC CARBOXY TERMINUS OF GENE 32 PROTEIN 1993
• INVITRO EVOLUTION OF INTRINSICALLY BENT DNA 1992
• SELECTION OF HIGH-AFFINITY RNA LIGANDS TO THE BACTERIOPHAGE-R17 COAT PROTEIN 1992
• THERMAL MOTIONS OF SURFACE ALPHA-HELICES IN THE D-GALACTOSE CHEMOSENSORY RECEPTOR - DETECTION BY DISULFIDE TRAPPING 1992
• Regulation of open complex formation at the Escherichia coli galactose operon promoters. Simultaneous interaction of RNA polymerase, gal repressor and CAP/cAMP. 1992
• 2-DIMENSIONAL CRYSTALS OF ESCHERICHIA-COLI MALTOPORIN AND THEIR INTERACTION WITH THE MALTOSE-BINDING PROTEIN 1992
• SELEXION - SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENT WITH INTEGRATED OPTIMIZATION BY NONLINEAR-ANALYSIS 1991
• Transcriptional organization of the Escherichia coli dnaX gene. 1991
• DETECTION OF ESCHERICHIA-COLI RIBOSOME BINDING AT TRANSLATION INITIATION SITES IN THE ABSENCE OF TRANSFER-RNA 1991
• INFLUENCE OF MESSENGER-RNA DETERMINANTS ON TRANSLATION INITIATION IN ESCHERICHIA-COLI 1991
• NUCLEAR-MAGNETIC-RESONANCE STUDIES OF THE HAMMERHEAD RIBOZYME DOMAIN - SECONDARY STRUCTURE FORMATION AND MAGNESIUM-ION DEPENDENCE 1991
• REGULATION OF SCALLOP MYOSIN BY MUTANT REGULATORY LIGHT-CHAINS 1990
• DETERMINING LOCAL CONFORMATIONAL VARIATIONS IN DNA - NUCLEAR-MAGNETIC-RESONANCE STRUCTURES OF THE DNA DUPLEXES D(CGCCTAATCG) AND D(CGTCACGCGC) GENERATED USING BACK-CALCULATION OF THE NUCLEAR OVERHAUSER EFFECT SPECTRA, A DISTANCE GEOMETRY ALGORITHM AND CONSTRAINED MOLECULAR-DYNAMICS 1990
• AUTOGENOUS TRANSLATIONAL OPERATOR RECOGNIZED BY BACTERIOPHAGE-T4 DNA-POLYMERASE 1990
• FULL-LENGTH RAT ALPHA AND BETA CARDIAC MYOSIN HEAVY-CHAIN SEQUENCES - COMPARISONS SUGGEST A MOLECULAR-BASIS FOR FUNCTIONAL DIFFERENCES 1989
• RIBONUCLEOPROTEIN COMPLEXES OF R17 COAT PROTEIN AND A TRANSLATIONAL OPERATOR ANALOG 1988
• ROLES OF OPERATOR AND NON-OPERATOR RNA SEQUENCES IN BACTERIOPHAGE R17 CAPSID ASSEMBLY 1988
• AUTOGENOUS REGULATORY SITE ON THE BACTERIOPHAGE-T4 GENE-32 MESSENGER-RNA 1988
• Solution structures of the rabbit neutrophil defensin NP-5 1988
• TRANSCRIPTIONAL ACTIVATION OF BACTERIOPHAGE-T4 MIDDLE PROMOTERS BY THE MOTA PROTEIN 1988
• 5' EXON REQUIREMENT FOR SELF-SPLICING OF THE TETRAHYMENA-THERMOPHILA PRE-RIBOSOMAL RNA AND IDENTIFICATION OF A CRYPTIC 5' SPLICE SITE IN THE 3' EXON 1987
• SEQUENCES AND STUDIES OF BACTERIOPHAGE-T4 RII-MUTANTS 1987
• TRANSLATIONAL REPRESSION - BIOLOGICAL-ACTIVITY OF PLASMID-ENCODED BACTERIOPHAGE T4-REGA PROTEIN 1987
• NEW REACTIONS OF THE RIBOSOMAL-RNA PRECURSOR OF TETRAHYMENA AND THE MECHANISM OF SELF-SPLICING 1986
• INFORMATION-CONTENT OF BINDING-SITES ON NUCLEOTIDE-SEQUENCES 1986
• Characterization of regions of the Caenorhabditis elegans X chromosome containing vitellogenin genes 1986
• Calibration of the angular dependence of the amide proton-Cα proton coupling constants, 3JHNα, in a globular protein 1984
• Cloning of a yolk protein gene family from Caenorhabditis elegans 1984
• ORGANIZATION AND EXPRESSION OF NON-ALU FAMILY INTERSPERSED REPETITIVE DNA-SEQUENCES IN THE MOUSE GENOME 1984
• Binding of yeast tRNAPhe anticodon arm to Escherichia coli 30 S ribosomes. 1983
• AUTO-REGULATION OF GENE-EXPRESSION - QUANTITATIVE-EVALUATION OF THE EXPRESSION AND FUNCTION OF THE BACTERIOPHAGE-T4 GENE-32 (SINGLE-STRANDED-DNA BINDING) PROTEIN SYSTEM 1982
• ANALYSIS INVIVO OF TRANSLATIONAL MUTANTS OF THE RIIB CISTRON OF BACTERIOPHAGE-T4 1981
• MUTATIONS THAT DETOXIFY AN ABERRANT T4 MEMBRANE-PROTEIN 1981
• RII CISTRONS OF BACTERIOPHAGE-T4 - DNA-SEQUENCE AROUND THE INTERCISTRONIC DIVIDE AND POSITIONS OF GENETIC LANDMARKS 1981
• TRANSLATIONAL REINITIATION IN THE RIIB CISTRON OF BACTERIOPHAGE-T4 1981
• In situ hybridization of three transfer RNAs to the polytene chromosomes of Drosophila melanogaster. 1980
• CHROMATIN STRUCTURE OF THE RIBOSOMAL-RNA GENES OF TETRAHYMENA-THERMOPHILA AS ANALYZED BY TRIMETHYLPSORALEN CROSSLINKING INVIVO 1980
• STUDIES ON GENE-CONTROL REGIONS .9. EFFECT OF HYPOXANTHINE-SUBSTITUTED LAC OPERATORS ON THE LAC OPERATOR LAC REPRESSOR INTERACTION 1979
• AUTOGENOUS TRANSLATIONAL REPRESSION OF BACTERIOPHAGE-T4 GENE-32 EXPRESSION INVITRO 1978
• STUDIES ON GENE CONTROL REGIONS .7. EFFECT OF 5-BROMOURACIL-SUBSTITUTED LAC OPERATORS ON LAC OPERATOR LAC REPRESSOR INTERACTION 1978
• Quantitative in situ hybridization of ribosomal RNA species to polytene chromosomes of Drosophila melanogaster. 1977
• MUTATION THAT CONFERS TEMPERATURE SENSITIVITY ON TRANSLATION OF RIIB IN BACTERIOPHAGE-T4 1976
• ORGANIZATION OF HIGHLY REPEATED SEQUENCES IN MOUSE MAIN-BAND DNA 1976
• Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 2. Chemical synthesis of the deoxypolynucleotide segments corresponding to the nucleotide sequence 1-31 1976
• Oligonucleotide binding to the native and denatured conformers of yeast transfer RNA-3 Lea. 1974
• Stability of ribonucleic acid double-stranded helices. 1974
• Circular dichroism of double-helical oligoribonucleotides. 1973
• Stability of RNA hairpin loops: A 6 -C m -U 6 . 1973
• CIII. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast 1972
• CIV. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. Chemical synthesis of an icosadeoxynucleotide corresponding to the nucleotide sequence 21 to 40 1972
• CX. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. Synthesis of three decadeoxynucleotides corresponding to the nucleotide sequence 51 to 70 1972
• CXI. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. Synthesis of a dodecadeoxynucleotide and a heptadeoxynucleotide corresponding to the nucleotide sequence 66 to 77 1972
• CXIV. Total synthesis of the structural gene for an alanine transfer RNA from yeast. Enzymic joining of the chemically synthesized segments to form the DNA duplex corresponding to nucleotide sequence 46 to 77 1972
• Complementary oligonucleotide binding to transfer RNA. 1972
• CXVII. Hybridization of polydeoxynucleotides with tyrosine transfer RNA sequences to the r-strand of φ80psu^+III DNA 1972
• Pre-replicative development of the bacteriophage T4: RNA and protein synthesis in vivo and in vitro 1971
• Transcription and translation of sheared bacteriophage T4 DNA in vitro 1971
• Translation of the UGA triplet in vitro by tryptophan transfer RNA's 1971
• Self-complementary oligoribonucleotides: adenylic acid-uridylic acid block copolymers. 1971
• Self-complementary oligoribonucleotides: effects of helix defects and guanylic acid-cytidylic acid base pairs. 1971