Journal of Molecular Biology
Journal
Overview
publication venue for
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Context-dependence of T-loop Mediated Long-range RNA Tertiary Interactions
2023
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Regulation of Gene Expression Through Effector-dependent Conformational Switching by Cobalamin Riboswitches
2022
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Merging Established Mechanisms with New Insights: Condensates, Hubs, and the Regulation of RNA Polymerase II Transcription
2022
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Two Classes of Myosin Inhibitors, Para-nitroblebbistatin and Mavacamten, Stabilize β-Cardiac Myosin in Different Structural and Functional States
2021
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RNA Polymerase II Transcription
2021
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The Role of XPB/Ssl2 dsDNA Translocase Processivity in Transcription Start-site Scanning
2021
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Release of Human TFIIB from Actively Transcribing Complexes Is Triggered upon Synthesis of 7-and 9-nt RNAs
2020
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Multiple Modes of Protein-Protein Interactions Promote RNP Granule Assembly
2018
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Transcription Factor–Mediator Interfaces: Multiple and Multi-Valent
2017
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The HMGB1 C-Terminal Tail Regulates DNA Bending
2016
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Noncoding RNAs: Regulators of the Mammalian Transcription Machinery
2016
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Macromolecular Complexes in Transcription and Co-Transcriptional RNA Processing
2016
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A Highly Coupled Network of Tertiary Interactions in the SAM-I Riboswitch and Their Role in Regulatory Tuning
2015
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Contributions of the TEL-patch Amino Acid Cluster on TPP1 to Telomeric DNA Synthesis by Human Telomerase
2015
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Dynamic and Thermodynamic Response of the Ras Protein Cdc42Hs upon Association with the Effector Domain of PAK3
2014
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Extracellular-Regulated Kinase 2 Is Activated by the Enhancement of Hinge Flexibility
2014
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Structure and Function of Steroid Receptor RNA Activator Protein, the Proposed Partner of SRA Noncoding RNA
2014
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Multiple C-Terminal Tails within a Single E. coli SSB Homotetramer Coordinate DNA Replication and Repair
2013
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Structural Insights into Transcriptional Repression by Noncoding RNAs That Bind to Human Pol II
2013
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The Non-Coding B2 RNA Binds to the DNA Cleft and Active-Site Region of RNA Polymerase II
2013
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Molecular Mechanism of Membrane Binding of the GRP1 PH Domain
2013
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Nucleotides Adjacent to the Ligand-Binding Pocket are Linked to Activity Tuning in the Purine Riboswitch
2013
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Insights into the Regulatory Landscape of the Lysine Riboswitch
2012
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Life's Simple Measures: Unlocking the Proteome
2012
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Activator-Mediator Binding Stabilizes RNA Polymerase II Orientation within the Human Mediator-RNA Polymerase II-TFIIF Assembly
2012
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Effects of Pathogenic Proline Mutations on Myosin Assembly
2012
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Community-Wide Assessment of Protein-Interface Modeling Suggests Improvements to Design Methodology
2011
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The Rate of Polymerase Release upon Filling the Gap between Okazaki Fragments Is Inadequate to Support Cycling during Lagging Strand Synthesis
2011
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Hotspot-Centric De Novo Design of Protein Binders
2011
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Polymerase Chaperoning and Multiple ATPase Sites Enable the E. coli DNA Polymerase III Holoenzyme to Rapidly Form Initiation Complexes
2011
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Structure of the BamC Two-Domain Protein Obtained by Rosetta with a Limited NMR Data Set
2011
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Multiple POT1-TPP1 Proteins Coat and Compact Long Telomeric Single-Stranded DNA
2011
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Crystal Structure of BamD: An Essential Component of the β-Barrel Assembly Machinery of Gram-Negative Bacteria
2011
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Membrane Docking Geometry and Target Lipid Stoichiometry of Membrane-Bound PKCα C2 Domain: A Combined Molecular Dynamics and Experimental Study
2010
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Processive Selenocysteine Incorporation during Synthesis of Eukaryotic Selenoproteins
2010
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RNA Polymerase II and TAFs Undergo a Slow Isomerization after the Polymerase Is Recruited to Promoter-Bound TFIID
2010
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Discrimination between Closely Related Cellular Metabolites by the SAM-I Riboswitch
2010
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Lattice Structure of Cytoplasmic Microtubules in a Cultured Mammalian Cell
2009
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Insights into the Dynamics of Specific Telomeric Single-Stranded DNA Recognition by Pot1pN
2009
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Understanding the sequence specificity of tRNA binding to elongation factor Tu using tRNA mutagenesis.
2009
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A Structural Basis for the Recognition of 2′-Deoxyguanosine by the Purine Riboswitch
2009
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Hydrogen-exchange mass spectrometry reveals activation-induced changes in the conformational mobility of p38 alpha MAP kinase
2008
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TFIIA changes the conformation of the DNA in TBP/TATA complexes and increases their kinetic stability
2007
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Directed mutagenesis identifies amino acid residues involved in elongation factor Tu binding to yeast Phe-tRNAPhe.
2007
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HURP wraps microtubule ends with an additional tubulin sheet that has a novel conformation of tubulin
2007
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Thermodynamic and kinetic characterization of ligand binding to the purine riboswitch aptamer domain (vol 359, pg 754, 2006)
2006
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A new model for Schizosaccharomyces pombe telomere recognition: The telomeric single-stranded DNA-binding activity of Pot1(1-389)
2006
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Thermodynamic and kinetic characterization of ligand binding to the purine riboswitch aptamer domain
2006
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The crystal structure of GCAP3 suggests molecular mechanism of GCAP-linked cone dystrophies
2006
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Alanine scanning of MS2 coat protein reveals protein-phosphate contacts involved in thermodynamic hot spots.
2006
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Quantitative analysis of deoxynucleotide substitutions in the codon-anticodon helix.
2006
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Divergent evolution within protein superfolds inferred from profile-based phylogenetics
2005
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Hydrogen exchange solvent protection by an ATP analogue reveals conformational changes in ERK2 upon activation
2005
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A three-dimensional cryo-electron microscopy structure of the bacteriophage φKZ head
2005
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A bipartite polymerase-processivity factor interaction: only the internal beta binding site of the alpha subunit is required for processive replication by the DNA polymerase III holoenzyme.
2005
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Caveolin-1 interacts directly with dynamin-2
2005
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Crystal Structures of Human DcpS in Ligand-free and m7GDP-bound forms Suggest a Dynamic Mechanism for Scavenger mRNA Decapping
2005
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Surface-decoration of microtubules by human Tau
2004
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The 12 Å structure of trypsin-treated measles virus N-RNA
2004
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Structural basis for telomeric single-stranded DNA recognition by yeast Cdc13
2004
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Kinetic analysis of site-specific photoaptamer-protein cross-linking
2004
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Structural distortion of p53 by the mutation R249S and its rescue by a designed peptide: implications for "mutant conformation".
2004
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Complex formation with kinesin motor domains affects the structure of microtubules
2004
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A structural analysis of the interaction between ncd tail and tubulin protofilaments
2003
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Towards an understanding of the poliovirus replication complex: The solution structure of the soluble domain of the poliovirus 3A protein
2003
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Quantitative analysis of aspartate receptor signaling complex reveals that the homogeneous two-state model is inadequate: Development of a heterogeneous two-state model
2003
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Refined solution structure of the iron-responsive element RNA using residual dipolar couplings
2003
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Functional analysis of the glutathione S-transferase 3 from Onchocerca volvulus (Ov-GST-3): A parasite GST confers increased resistance to oxidative stress in Caenorhabditis elegans
2003
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The carboxy-terminal domain of the DExD/H protein YxiN is sufficient to confer specificity for 23 S rRNA
2002
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Crystal structure of HsIUV complexed with a vinyl sulfone inhibitor: Corroboration of a proposed mechanism of allosteric activation of HsIV by HsIU
2002
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The HIV plus-strand transfer reaction: determination of replication-competent intermediates and identification of a novel lentiviral element, the primer over-extension sequence.
2002
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Kinetic and mechanistic analysis of the RNA polymerase II transcription reaction at the human interleukin-2 promoter
2001
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Kinetic and mechanistic analysis of the RNA polymerase II transcrption reaction at the human interleukin-2 promoter.
2001
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Modifying the specificity of an RNA backbone contact
2001
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Identification of thermodynamically relevant interactions between EF-Tu and backbone elements of tRNA
2001
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Structural and energetic analysis of RNA recognition by a universally conserved protein from the signal recognition particle
2001
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Polymerization, three-dimensional structure and mechanical properties of Dictyostelium versus rabbit muscle actin filaments
2000
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A new look at the microtubule binding patterns of dimeric kinesins
2000
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Comparative sequence analysis of the complete human sarcomeric myosin heavy chain family: Implications for functional diversity
1999
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Nicotinic acetylcholine receptor at 4.6 Å resolution:: Transverse tunnels in the channel wall
1999
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Identification of the acidic residues in the active site of DNA polymerase III.
1999
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NMR solution structure of the lead-dependent ribozyme: Evidence for dynamics in RNA catalysis
1998
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Order, dynamics and metal-binding in the lead-dependent ribozyme
1998
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An atomic model of crystalline actin tubes: Combining electron microscopy with X-ray crystallography
1998
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The mathematics of SELEX against complex targets
1998
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The effects of salt on the TATA binding protein-DNA interaction from a hyperthermophilic archaeon
1998
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Structure and dynamics of the iron responsive element RNA: Implications for binding of the RNA by iron regulatory binding proteins
1997
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Solution structure of the first three zinc fingers of TFIIIA bound to the cognate DNA sequence: determinants of affinity and sequence specificity.
1997
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A DNA polymerase III holoenzyme-like subassembly from an extreme thermophilic eubacterium.
1997
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Crystals by design: A strategy for crystallization of a ribozyme derived from the Tetrahymena group I intron
1997
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A 29 residue region of the sarcomeric myosin rod is necessary for filament formation
1997
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Motor domains of kinesin and ncd interact with microtubule protofilaments with the same binding geometry
1997
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A network of heterogeneous hydrogen bonds in GNRA tetraloops
1996
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The crystal structure of a hyperthermophilic archaeal TATA-box binding protein.
1996
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Bent pseudoknots and novel RNA inhibitors of type 1 human immunodeficiency virus (HIV-1) reverse transcriptase
1996
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Polarity of 2-D and 3-D maps of tubulin sheets and motor-decorated sheets
1996
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Interaction of the Bacillus stearothermophilus ribosomal protein S15 with 16 S rRNA .1. Defining the minimal RNA site
1996
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Interaction of the Bacillus stearothermophilus ribosomal protein S15 with 16 S rRNA .2. Specificity determinants of RNA-protein recognition
1996
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In vitro evolution of the DNA binding sites of Escherichia coli methionine repressor, MetJ
1996
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IN-VITRO SELECTION OF SMALL RNAS THAT BIND TO ESCHERICHIA-COLI PHENYLALANYL-TRANSFER-RNA SYNTHETASE
1994
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GAAA TETRALOOP AND CONSERVED BULGE STABILIZE TERTIARY STRUCTURE OF A GROUP-I INTRON DOMAIN
1994
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VISUALIZATION OF A TERTIARY STRUCTURAL DOMAIN OF THE TETRAHYMENA GROUP-I INTRON BY ELECTRON-MICROSCOPY
1994
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TRANSLATION INITIATION COMPLEX-FORMATION WITH 30-S RIBOSOMAL PARTICLES MUTATED AT CONSERVED POSITIONS IN THE 3'-MINOR DOMAIN OF 16-S RNA
1993
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THE ORIENTATION OF PORIN OMPF IN THE OUTER-MEMBRANE OF ESCHERICHIA-COLI
1993
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AN EFFICIENT PROCEDURE FOR ASSIGNMENT OF THE PROTON, CARBON AND NITROGEN RESONANCES IN C-13/N-15 LABELED NUCLEIC-ACIDS
1993
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2-DIMENSIONAL CRYSTALLIZATION OF THE LIGHT-HARVESTING COMPLEX FROM RHODOSPIRILLUM-RUBRUM
1993
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ASSEMBLY OF THE BACTERIOPHAGE-T4 REPLICATION MACHINE REQUIRES THE ACIDIC CARBOXY TERMINUS OF GENE 32 PROTEIN
1993
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INVITRO EVOLUTION OF INTRINSICALLY BENT DNA
1992
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SELECTION OF HIGH-AFFINITY RNA LIGANDS TO THE BACTERIOPHAGE-R17 COAT PROTEIN
1992
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THERMAL MOTIONS OF SURFACE ALPHA-HELICES IN THE D-GALACTOSE CHEMOSENSORY RECEPTOR - DETECTION BY DISULFIDE TRAPPING
1992
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Regulation of open complex formation at the Escherichia coli galactose operon promoters. Simultaneous interaction of RNA polymerase, gal repressor and CAP/cAMP.
1992
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2-DIMENSIONAL CRYSTALS OF ESCHERICHIA-COLI MALTOPORIN AND THEIR INTERACTION WITH THE MALTOSE-BINDING PROTEIN
1992
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SELEXION - SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENT WITH INTEGRATED OPTIMIZATION BY NONLINEAR-ANALYSIS
1991
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Transcriptional organization of the Escherichia coli dnaX gene.
1991
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DETECTION OF ESCHERICHIA-COLI RIBOSOME BINDING AT TRANSLATION INITIATION SITES IN THE ABSENCE OF TRANSFER-RNA
1991
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INFLUENCE OF MESSENGER-RNA DETERMINANTS ON TRANSLATION INITIATION IN ESCHERICHIA-COLI
1991
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NUCLEAR-MAGNETIC-RESONANCE STUDIES OF THE HAMMERHEAD RIBOZYME DOMAIN - SECONDARY STRUCTURE FORMATION AND MAGNESIUM-ION DEPENDENCE
1991
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REGULATION OF SCALLOP MYOSIN BY MUTANT REGULATORY LIGHT-CHAINS
1990
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DETERMINING LOCAL CONFORMATIONAL VARIATIONS IN DNA - NUCLEAR-MAGNETIC-RESONANCE STRUCTURES OF THE DNA DUPLEXES D(CGCCTAATCG) AND D(CGTCACGCGC) GENERATED USING BACK-CALCULATION OF THE NUCLEAR OVERHAUSER EFFECT SPECTRA, A DISTANCE GEOMETRY ALGORITHM AND CONSTRAINED MOLECULAR-DYNAMICS
1990
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AUTOGENOUS TRANSLATIONAL OPERATOR RECOGNIZED BY BACTERIOPHAGE-T4 DNA-POLYMERASE
1990
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FULL-LENGTH RAT ALPHA AND BETA CARDIAC MYOSIN HEAVY-CHAIN SEQUENCES - COMPARISONS SUGGEST A MOLECULAR-BASIS FOR FUNCTIONAL DIFFERENCES
1989
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RIBONUCLEOPROTEIN COMPLEXES OF R17 COAT PROTEIN AND A TRANSLATIONAL OPERATOR ANALOG
1988
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ROLES OF OPERATOR AND NON-OPERATOR RNA SEQUENCES IN BACTERIOPHAGE R17 CAPSID ASSEMBLY
1988
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AUTOGENOUS REGULATORY SITE ON THE BACTERIOPHAGE-T4 GENE-32 MESSENGER-RNA
1988
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Solution structures of the rabbit neutrophil defensin NP-5
1988
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TRANSCRIPTIONAL ACTIVATION OF BACTERIOPHAGE-T4 MIDDLE PROMOTERS BY THE MOTA PROTEIN
1988
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5' EXON REQUIREMENT FOR SELF-SPLICING OF THE TETRAHYMENA-THERMOPHILA PRE-RIBOSOMAL RNA AND IDENTIFICATION OF A CRYPTIC 5' SPLICE SITE IN THE 3' EXON
1987
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SEQUENCES AND STUDIES OF BACTERIOPHAGE-T4 RII-MUTANTS
1987
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TRANSLATIONAL REPRESSION - BIOLOGICAL-ACTIVITY OF PLASMID-ENCODED BACTERIOPHAGE T4-REGA PROTEIN
1987
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NEW REACTIONS OF THE RIBOSOMAL-RNA PRECURSOR OF TETRAHYMENA AND THE MECHANISM OF SELF-SPLICING
1986
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INFORMATION-CONTENT OF BINDING-SITES ON NUCLEOTIDE-SEQUENCES
1986
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Characterization of regions of the Caenorhabditis elegans X chromosome containing vitellogenin genes
1986
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Calibration of the angular dependence of the amide proton-Cα proton coupling constants, 3JHNα, in a globular protein
1984
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Cloning of a yolk protein gene family from Caenorhabditis elegans
1984
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ORGANIZATION AND EXPRESSION OF NON-ALU FAMILY INTERSPERSED REPETITIVE DNA-SEQUENCES IN THE MOUSE GENOME
1984
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Binding of yeast tRNAPhe anticodon arm to Escherichia coli 30 S ribosomes.
1983
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AUTO-REGULATION OF GENE-EXPRESSION - QUANTITATIVE-EVALUATION OF THE EXPRESSION AND FUNCTION OF THE BACTERIOPHAGE-T4 GENE-32 (SINGLE-STRANDED-DNA BINDING) PROTEIN SYSTEM
1982
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ANALYSIS INVIVO OF TRANSLATIONAL MUTANTS OF THE RIIB CISTRON OF BACTERIOPHAGE-T4
1981
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MUTATIONS THAT DETOXIFY AN ABERRANT T4 MEMBRANE-PROTEIN
1981
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RII CISTRONS OF BACTERIOPHAGE-T4 - DNA-SEQUENCE AROUND THE INTERCISTRONIC DIVIDE AND POSITIONS OF GENETIC LANDMARKS
1981
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TRANSLATIONAL REINITIATION IN THE RIIB CISTRON OF BACTERIOPHAGE-T4
1981
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In situ hybridization of three transfer RNAs to the polytene chromosomes of Drosophila melanogaster.
1980
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CHROMATIN STRUCTURE OF THE RIBOSOMAL-RNA GENES OF TETRAHYMENA-THERMOPHILA AS ANALYZED BY TRIMETHYLPSORALEN CROSSLINKING INVIVO
1980
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IMMUNOSPECIFIC IDENTIFICATION AND 3-DIMENSIONAL STRUCTURE OF A MEMBRANE-BOUND ACETYLCHOLINE-RECEPTOR FROM TORPEDO-CALIFORNICA
1979
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STUDIES ON GENE-CONTROL REGIONS .9. EFFECT OF HYPOXANTHINE-SUBSTITUTED LAC OPERATORS ON THE LAC OPERATOR LAC REPRESSOR INTERACTION
1979
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AUTOGENOUS TRANSLATIONAL REPRESSION OF BACTERIOPHAGE-T4 GENE-32 EXPRESSION INVITRO
1978
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STUDIES ON GENE CONTROL REGIONS .7. EFFECT OF 5-BROMOURACIL-SUBSTITUTED LAC OPERATORS ON LAC OPERATOR LAC REPRESSOR INTERACTION
1978
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Quantitative in situ hybridization of ribosomal RNA species to polytene chromosomes of Drosophila melanogaster.
1977
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STRUCTURAL STUDIES OF A MEMBRANE-BOUND ACETYLCHOLINE-RECEPTOR FROM TORPEDO-CALIFORNICA
1977
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MUTATION THAT CONFERS TEMPERATURE SENSITIVITY ON TRANSLATION OF RIIB IN BACTERIOPHAGE-T4
1976
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ORGANIZATION OF HIGHLY REPEATED SEQUENCES IN MOUSE MAIN-BAND DNA
1976
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Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 2. Chemical synthesis of the deoxypolynucleotide segments corresponding to the nucleotide sequence 1-31
1976
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Oligonucleotide binding to the native and denatured conformers of yeast transfer RNA-3 Lea.
1974
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Stability of ribonucleic acid double-stranded helices.
1974
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Circular dichroism of double-helical oligoribonucleotides.
1973
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Stability of RNA hairpin loops: A 6 -C m -U 6 .
1973
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CIII. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast
1972
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CIV. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. Chemical synthesis of an icosadeoxynucleotide corresponding to the nucleotide sequence 21 to 40
1972
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CX. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. Synthesis of three decadeoxynucleotides corresponding to the nucleotide sequence 51 to 70
1972
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CXI. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. Synthesis of a dodecadeoxynucleotide and a heptadeoxynucleotide corresponding to the nucleotide sequence 66 to 77
1972
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CXIV. Total synthesis of the structural gene for an alanine transfer RNA from yeast. Enzymic joining of the chemically synthesized segments to form the DNA duplex corresponding to nucleotide sequence 46 to 77
1972
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Complementary oligonucleotide binding to transfer RNA.
1972
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CXVII. Hybridization of polydeoxynucleotides with tyrosine transfer RNA sequences to the r-strand of φ80psu^+III DNA
1972
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Pre-replicative development of the bacteriophage T4: RNA and protein synthesis in vivo and in vitro
1971
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Transcription and translation of sheared bacteriophage T4 DNA in vitro
1971
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Translation of the UGA triplet in vitro by tryptophan transfer RNA's
1971
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Self-complementary oligoribonucleotides: adenylic acid-uridylic acid block copolymers.
1971
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Self-complementary oligoribonucleotides: effects of helix defects and guanylic acid-cytidylic acid base pairs.
1971
Research
keywords
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0601 Biochemistry and Cell Biology, 0304 Medicinal and Biomolecular Chemistry