Journal of Applied Physiology
Journal
Overview
publication venue for
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Athletics should embrace technology, not nostalgia.
2024
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When does technology become too advanced for track and field?
2024
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Effects of prosthetic stiffness and added mass on metabolic power and asymmetry in female runners with a leg amputation
2024
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Is it the people or the place? The remarkable 30-year period of integrative physiology research in the Carlson Gymnasium at the University of Colorado Boulder.
2024
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Writing effective letters of recommendation in physiology
2024
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Reply to Dr. Mougios
2024
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Scientific writing in physiology: confused/misused terms and phrases
2024
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The Tour de France, also possible for mortals? A comparison of a recreational and a World Tour cyclist
2024
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Endothelial-derived extracellular vesicles associated with electronic cigarette use impair cerebral microvascular cell function
2023
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Improvement in Cardiac Function and Regional LV Strain Following Intramyocardial Injection of a Hydrogel Early Post Myocardial Infarction in a Porcine Model
2023
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It is time to abandon single-value oxygen uptake energy equivalents
2023
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A multi-trial, retrospective analysis of the antihypertensive effects of high-resistance, low-volume inspiratory muscle strength training
2022
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Suppression of trimethylamine N-oxide with DMB mitigates vascular dysfunction, exercise intolerance, and frailty associated with a Western-style diet in mice
2022
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The metabolic cost of emulated aerodynamic drag forces in marathon running
2022
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To grant you an edge. Part 3. Considerations for writing competitive research career development proposals in the biomedical sciences
2022
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To grant you an edge: Part 1. General strategies for writing competitive biomedical research proposals
2022
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To grant you an edge: Part 2. Tactical tips for addressing specific aspects of biomedical research proposals
2022
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Musings on mentoring: teach your "children" well
2022
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Distribution of motor unit properties across human muscles
2022
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A (Baker's) dozen tips for enhancing early-stage academic career development in biomedical research
2021
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The academic biomedical research laboratory as a "small business"
2021
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Endothelin-1-induced endothelial microvesicles impair endothelial cell function
2020
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Effects of resveratrol or estradiol on postexercise endothelial function in estrogen-deficient postmenopausal women
2020
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Time-efficient physical training for enhancing cardiovascular function in midlife and older adults: promise and current research gaps
2019
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Hopping with degressive spring stiffness in a full-leg exoskeleton lowers metabolic cost compared with progressive spring stiffness and hopping without assistance
2019
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The historical context and scientific legacy of John O. Holloszy
2019
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Effects of HIV-1 gp120 and TAT-derived microvesicles on endothelial cell function
2019
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Healthy lifestyle-based approaches for successful vascular aging
2018
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Vascular aging
2018
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Habitual aerobic exercise and circulating proteomic patterns in healthy adults: relation to indicators of healthspan
2018
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Intraocular pressure and cardiovascular alterations investigated in artificial gravity as a countermeasure to spaceflight associated neuro-ocular syndrome
2018
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Last Word on Viewpoint: Use aerobic energy expenditure instead of oxygen uptake to quantify exercise intensity and predict endurance performance
2018
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Use aerobic energy expenditure instead of oxygen uptake to quantify exercise intensity and predict endurance performance
2018
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Mitochondria-targeted antioxidant therapy with MitoQ ameliorates aortic stiffening in old mice
2018
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The biomechanics of the fastest sprinter with a unilateral transtibial amputation
2018
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Ocular changes over 60 min in supine and prone postures
2017
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Prosthetic model, but not stiffness or height, affects the metabolic cost of running for athletes with unilateral transtibial amputations
2017
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Reduced prosthetic stiffness lowers the metabolic cost of running for athletes with bilateral transtibial amputations
2017
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Habitual aerobic exercise does not protect against micro-or macrovascular endothelial dysfunction in healthy estrogen-deficient postmenopausal women
2017
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Force steadiness as a predictor of time to complete a pegboard test of dexterity in young men and women
2016
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Fatigue-induced adjustment in antagonist coactivation by old adults during a steadiness task
2016
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Acute effects of changes to the gravitational vector on the eye
2016
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Effects of sodium nitrite supplementation on vascular function and related small metabolite signatures in middle-aged and older adults
2016
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Energetics of vertical kilometer foot races; is steeper cheaper?
2016
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Inappropriate interpretation of surface EMG signals and muscle fiber characteristics impedes understanding of the control of neuromuscular function
2015
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Modulation of motor unit activity in biceps brachii by neuromuscular electrical stimulation applied to the contralateral arm
2015
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Reply to De Luca, Nawab, and Kline: The proposed method to validate surface EMG signal decomposition remains problematic
2015
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Sodium nitrite supplementation improves motor function and skeletal muscle inflammatory profile in old male mice
2015
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The extraction of neural strategies from the surface EMG: an update
2014
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Glial TLR4 signaling does not contribute to opioid-induced depression of respiration
2014
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Edward F. Adolph Distinguished Lecture: The remarkable anti-aging effects of aerobic exercise on systemic arteries
2014
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The effect of spaceflight on mouse olfactory bulb volume, neurogenesis, and cell death indicates the protective effect of novel environment
2014
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Inorganic nitrite supplementation for healthy arterial aging
2014
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Vascular endothelial function and oxidative stress are related to dietary niacin intake among healthy middle-aged and older adults
2014
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PET/CT imaging of age- and task-associated differences in muscle activity during fatiguing contractions
2013
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Discharge properties of motor units during steady isometric contractions performed with the dorsiflexor muscles
2012
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Akt and MAPK signaling mediate pregnancy-induced cardiac adaptation
2012
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The energetic cost of maintaining lateral balance during human running
2012
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Plasma norepinephrine is an independent predictor of vascular endothelial function with aging in healthy women
2011
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Exercise-induced cardiac preconditioning: how exercise protects your achy-breaky heart
2011
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Neuromuscular adjustments that constrain submaximal EMG amplitude at task failure of sustained isometric contractions
2011
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Bouncing to conclusions: clear evidence for the metabolic cost of generating muscular force
2011
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Muscle activity and time to task failure differ with load compliance and target force for elbow flexor muscles
2011
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Human aging and CD31+ T-cell number, migration, apoptotic susceptibility, and telomere length
2010
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Cancellous bone adaptation to tibial compression is not sex dependent in growing mice
2010
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Myostatin expression is increased by food deprivation in a muscle-specific manner and contributes to muscle atrophy during prolonged food deprivation in mice
2010
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Epigenetics: an emerging player in health and disease
2010
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An integrative model of motor unit activity during sustained submaximal contractions
2010
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Recruitment and derecruitment characteristics of motor units in a hand muscle of young and old adults
2010
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Counterpoint: Artificial legs do not make artificially fast running speeds possible.
2010
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Implantation increases tensile strength and collagen content of self-assembled tendon constructs
2010
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Last Word on Point:Counterpoint: Artificial limbs do/do not make artificially fast running speeds possible
2010
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Point:Counterpoint: Artificial limbs do/do not make artificially fast running speeds possible
2010
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Leg exoskeleton reduces the metabolic cost of human hopping
2009
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The fastest runner on artificial legs: different limbs, similar function?
2009
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THE INTERPOLATED TWITCH AND THE FORCE CAPACITY OF MUSCLE
2009
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Effects of spaceflight on innate immune function and antioxidant gene expression
2009
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Pound for pound: Working out how obesity influences the energetics of walking
2009
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Effects of spaceflight on murine skeletal muscle gene expression
2009
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Shifts in bone marrow cell phenotypes caused by spaceflight
2009
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Spaceflight effects on T lymphocyte distribution, function and gene expression
2009
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IT IS NOT A WAVELET ANALYSIS
2008
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MOTOR UNIT RECRUITMENT THRESHOLD
2008
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Cytochrome P-450 2C9 signaling does not contribute to age-associated vascular endothelial dysfunction in humans
2008
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Habitual exercise and arterial aging
2008
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Independent effects of weight and mass on plantar flexor activity during walking: implications for their contributions to body support and forward propulsion
2008
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Decreased maximal heart rate with aging is related to reduced β-adrenergic responsiveness but is largely explained by a reduction in intrinsic heart rate
2008
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Electromyographic measures of muscle activation and changes in muscle architecture of human elbow flexors during fatiguing contractions
2008
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Short-term treadmill running in the rat: what kind of stressor is it?
2007
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High-dose ascorbic acid infusion abolishes chronic vasoconstriction and restores resting leg blood flow in healthy older men
2007
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Perspectives in innate and acquired cardioprotection: cardioprotection acquired through exercise
2007
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Acquired and innate cardioprotection
2007
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Thermic effect of food and beta-adrenergic thermogenic responsiveness in habitually exercising and sedentary healthy adult humans
2007
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Matrix metalloproteinase-1 therapy improves muscle healing
2007
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Point: Counterpoint "The lactate paradox does/does not occur during exercise at high altitude" - Response
2007
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Accessory muscle activity contributes to the variation in time to task failure for different arm postures and loads
2007
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Accessory muscle activity contributes to the variation in time to task failure for different arm postures and loads.
2007
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Aging, exercise, and endothelial progenitor cell clonogenic and migratory capacity in men
2007
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Commentary on viewpoint "Human experimentation: No accurate, quantitative data"?
2007
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Oxidative stress contributes to chronic leg vasoconstriction in estrogen-deficient postmenopausal women
2007
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Sensitivity of the cross-correlaton between simulated surface EMGs for two muscles to detect motor unit synchronization
2007
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Impaired flow-mediated dilation with age is not explained by L-arginine bioavailability or endothelial asymmetric dimethylarginine protein expression
2007
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Training adaptations in the behavior of human motor units
2006
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Highlighted topic - Neural changes associated with training
2006
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Neural changes associated with training.
2006
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Regional variation of tibialis anterior tendon mechanics is lost following denervation
2006
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Sexual dimorphism of the intracellular heat shock protein 72 response
2006
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Amplitude cancellation reduces the size of motor unit potentials averaged from the surface EMG
2006
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Effects of obesity and sex on the energetic cost and preferred speed of walking
2006
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Positive effects of intermittent hypoxia (live high : train low) on exercise performance are/are not mediated primarily by augmented red cell volume - Point : counterpoint comments
2006
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Adrenergic receptors mediate stress-induced elevations in extracellular Hsp72
2005
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Prolonged muscle vibration increases stretch reflex amplitude, motor unit discharge rate, and force fluctuations in a hand muscle
2005
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Expression of phospholemman and its association with Na+-K+-ATPase in skeletal muscle:: effects of aging and exercise training
2005
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Muscle endurance is greater for old men compared with strength-matched young men
2005
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Task failure during fatiguing contractions performed by humans
2005
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Energy cost and muscular activity required for leg swing during walking
2005
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Metabolic energy and muscular activity required for leg swing in running
2005
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Practice reduces motor unit discharge variability in a hand muscle and improves manual dexterity in old adults
2005
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Ascorbic acid does not affect the age-associated reduction in maximal cardiac output and oxygen consumption in healthy adults
2005
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Independent metabolic costs of supporting body weight and accelerating body mass during walking
2005
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Influence of amplitude cancellation on the simulated surface electromyogram
2005
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Influence of aging on sex differences in muscle fatigability
2004
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Influence of age and physical activity on the primary in vivo antibody and T cell-mediated responses in men
2004
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The 1-to 2-Hz oscillations in muscle force are exacerbated by stress, especially in older adults
2004
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Men are more fatigable than strength-matched women when performing intermittent submaximal contractions
2004
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Strength training reduces force fluctuations during anisometric contractions of the quadriceps femoris muscles in old adults
2004
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The extraction of neural strategies from the surface EMG
2004
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Fatigability of the elbow flexor muscles for a sustained submaximal contraction is similar in men and women matched for strength
2004
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Plasma C-reactive protein is not elevated in physically active postmenopausal women taking hormone replacement therapy
2004
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Exercise training preserves coronary flow and reduces infarct size after ischemia-reperfusion in rat heart
2003
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No effect of menstrual cycle phase on lactate threshold
2003
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Skeletal muscle adaptations to microgravity exposure in the mouse
2003
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Circulating cytokines and endotoxin are not necessary for the activation of the sickness or corticosterone response produced by peripheral E-coli challenge
2003
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Influence of age and run training on cardiac Na+/Ca2+ exchange
2003
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Invited review: Dynamic exercise performance in Masters athletes: insight into the effects of primary human aging on physiological functional capacity
2003
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Mild renal hypertension alters run training effects on the frequency response of rat cardiomyocyte mechanics
2003
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Preventing annoyance from odors in spaceflight: a method for evaluating the sensory impact of rodent housing
2003
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Loss of desmin leads to impaired voluntary wheel running and treadmill exercise performance
2003
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B-1 cell (CD5+/CD11b+) numbers and nIgM levels are elevated in physically active vs. sedentary rats
2003
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Fluctuations in acceleration during voluntary contractions lead to greater impairment of movement accuracy in old adults
2003
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Metabolic cost of generating muscular force in human walking: insights from load-carrying and speed experiments
2003
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Activation among the elbow flexor muscles differs when maintaining arm position during a fatiguing contraction
2003
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Greater rate of decline in maximal aerobic capacity with age in endurance-trained than in sedentary men
2003
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Energy cost and muscular activity required for propulsion during walking
2003
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Genetic models in applied physiology - Selected contribution: Effects of spaceflight on immunity in the C57BL/6 mouse. I. Immune population distributions
2003
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Genetic models in applied physiology - Selected contribution: Effects of spaceflight on immunity in the C57BL/6 mouse. II. Activation, cytokines, erythrocytes, and platelets
2003
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Genetic models in applied physiology: selected contribution: effects of spaceflight on immunity in the C57BL/6 mouse. I. Immune population distributions.
2003
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Contralateral activity in a homologous hand muscle during voluntary contractions is greater in old adults
2003
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Declines in physiological functional capacity with age: a longitudinal study in peak swimming performance
2003
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Increased serum nIgM in voluntarily physically active rats: a potential role for B-1 cells
2003
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Changes in muscle activation can prolong the endurance time of a submaximal isometric contraction in humans
2003
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Role of extracellular HSP72 in acute stress-induced potentiation of innate immunity in active rats
2003
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Decline in insulin action with age in endurance-trained humans
2002
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Nonuniform activation of the agonist muscle does not covary with index finger acceleration in old adults
2002
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Elevated IL-1 beta contributes to antibody suppression produced by stress
2002
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Changes in maximal aerobic capacity with age in endurance-trained women: 7-yr follow-up
2002
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Genetic variability in forced and voluntary endurance exercise performance in seven inbred mouse strains
2002
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Exercise training alters an anoxia-induced, glibenclamide-sensitive current in rat ventricular cardiocytes
2002
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Regular aerobic exercise and the age-related increase in carotid artery intima-media thickness in healthy men
2002
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Older adults are less steady during submaximal isometric contractions with the knee extensor muscles
2002
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Skeletal muscle adaptations in response to voluntary wheel running in myosin heavy chain null mice
2002
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Sex differences in the fatigability of arm muscles depends on absolute force during isometric contractions
2001
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Glibenclamide improves postischemic recovery of myocardial contractile function in trained and sedentary rats
2001
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Maximal aerobic capacity across age in healthy Hispanic and Caucasian women
2001
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Activation of the arousal response can impair performance on a simple motor task
2001
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Women at altitude: short-term exposure to hypoxia and/or alpha(1)-adrenergic blockade reduces insulin sensitivity
2001
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Renal hypertension prevents run training modification of cardiomyocyte diastolic Ca2+ regulation in male rats
2001
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Cardiac and skeletal muscle adaptations to voluntary wheel running in the mouse
2001
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Sprint training shortens prolonged action potential duration in postinfarction rat myocyte: mechanisms
2001
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Endurance training alters outward K+ current characteristics in rat cardiocytes
2001
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Activation of the arousal response and impairment of performance increase with anxiety and stressor intensity
2001
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Alterations in enzymes involved in fat metabolism after acute and chronic altitude exposure
2001
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Catecholamine responses to alpha-adrenergic blockade during exercise in women acutely exposed to altitude
2001
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Interleukin-6 response to exercise and high-altitude exposure:: influence of α-adrenergic blockade
2001
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Long-term activity in upper- and lower-limb muscles of humans
2001
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Sprint training restores normal contractility in postinfarction rat myocytes
2000
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Coactivation of the antagonist muscle does not covary with steadiness in old adults
2000
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Sprint training normalizes Ca2+ transients and SR function in postinfarction rat myocytes
2000
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Women at altitude: carbohydrate utilization during exercise at 4,300 m
2000
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Women at altitude: energy requirement at 4,300 m
2000
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In situ SR function in postinfarction myocytes
1999
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Strength training improves the steadiness of slow lengthening contractions performed by old adults
1999
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Differential expression of stress proteins in rat myocardium after free wheel or treadmill run training
1999
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Effects of chronic run training on Na+-dependent Ca2+ efflux from rat left ventricular myocytes
1999
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Metabolic cost of generating horizontal forces during human running
1999
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Walking in simulated reduced gravity: mechanical energy fluctuations and exchange
1999
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Shortening and [Ca2+] dynamics of left ventricular myocytes isolated from exercise-trained rats
1998
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O-2 extraction maintains O-2 uptake during submaximal exercise with beta-adrenergic blockade at 4,300 m
1998
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Catecholamine response during 12 days of high-altitude exposure (4,300 m) in women
1998
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Sprint training attenuates myocyte hypertrophy and improves Ca2+ homeostasis in postinfarction myocytes
1998
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Alterations in myocardial signal transduction due to aging and chronic dynamic exercise
1998
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Force-treadmill for measuring vertical and horizontal ground reaction forces
1998
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Older adults can maximally activate the biceps brachii muscle by voluntary command
1998
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Greater rate of decline in maximal aerobic capacity with age in physically active vs. sedentary healthy women
1997
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Age-related declines in maximal aerobic capacity in regularly exercising vs. sedentary women: A meta-analysis
1997
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Norepinephrine spillover at rest and during submaximal exercise in young and old subjects
1997
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Age and gender interactions in physiological functional capacity: Insight from swimming performance
1997
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Blood pressure risk factors in healthy postmenopausal women: Physical activity and hormone replacement
1997
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Eccentric contractions require unique activation strategies by the nervous system
1996
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Muscle fiber hypertrophy: Hyperplasia, and capillary density in college men after resistance training
1996
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LESSER VAGAL WITHDRAWAL DURING ISOMETRIC-EXERCISE WITH AGE
1995
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PHYSIOLOGICAL DETERMINANTS OF 10-KM PERFORMANCE IN HIGHLY TRAINED FEMALE RUNNERS OF DIFFERENT AGES
1995
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REDUCED MOTOR UNIT ACTIVATION OF MUSCLE-SPINDLES AND TENDON ORGANS IN THE IMMOBILIZED CAT HINDLIMB
1995
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SHORT-TERM IMMOBILIZATION HAS A MINIMAL EFFECT ON THE STRENGTH AND FATIGABILITY OF A HUMAN HAND MUSCLE
1995
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TRAINING-RELATED ENHANCEMENT IN THE CONTROL OF MOTOR OUTPUT IN ELDERLY HUMANS
1994
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MAXIMAL AEROBIC CAPACITY AND TOTAL BLOOD-VOLUME IN HIGHLY TRAINED MIDDLE-AGED AND OLDER FEMALE ENDURANCE ATHLETES
1994
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ARM MUSCLE SYMPATHETIC-NERVE ACTIVITY DURING PREPARATION FOR AND INITIATION OF LEG-CYCLING EXERCISE IN HUMANS
1994
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ENDURANCE EXERCISE TRAINING IS ASSOCIATED WITH ELEVATED BASAL SYMPATHETIC-NERVE ACTIVITY IN HEALTHY OLDER HUMANS
1994
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SENSITIVITY OF MUSCLE PROTON SPIN-SPIN RELAXATION-TIME AS AN INDEX OF MUSCLE ACTIVATION
1994
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BEHAVIOR OF MOTOR UNITS IN HUMAN BICEPS BRACHII DURING A SUBMAXIMAL FATIGUING CONTRACTION
1994
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TOTAL BLOOD-VOLUME IN HEALTHY-YOUNG AND OLDER MEN
1994
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SYSTEMIC HYPERTENSION AT 4,300 M IS RELATED TO SYMPATHOADRENAL ACTIVITY
1994
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BETA-ADRENERGIC-BLOCKADE DOES NOT PREVENT THE LACTATE RESPONSE TO EXERCISE AFTER ACCLIMATIZATION TO HIGH-ALTITUDE
1994
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EXERCISE TRAINING DOES NOT COMPENSATE FOR AGE-RELATED DECREASE IN MYOCARDIAL GLUT-4 CONTENT
1994
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INFLUENCE OF ACTIVE MUSCLE SIZE ON SYMPATHETIC-NERVE DISCHARGE DURING ISOMETRIC CONTRACTIONS IN HUMANS
1993
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ECHOCARDIOGRAPHIC EVALUATION OF SIZE, FUNCTION, AND MASS OF NORMAL AND HYPERTROPHIED RAT VENTRICLES
1993
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AGE-RELATED IMMUNOSENESCENCE IN FISCHER 344 RATS - INFLUENCE OF EXERCISE TRAINING
1992
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NEUROBIOLOGY OF MUSCLE FATIGUE
1992
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A COMPARISON OF THE OXYGEN DRIFT IN DOWNHILL VS LEVEL RUNNING
1992
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PLASMA-CATECHOLAMINE AND LACTATE RESPONSE DURING GRADED-EXERCISE WITH VARIED GLYCOGEN CONDITIONS
1991
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DECREASED RELIANCE ON LACTATE DURING EXERCISE AFTER ACCLIMATIZATION TO 4,300M
1991
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OXYGEN-TRANSPORT DURING STEADY-STATE SUBMAXIMAL EXERCISE IN CHRONIC HYPOXIA
1991
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INCREASED DEPENDENCE ON BLOOD-GLUCOSE AFTER ACCLIMATIZATION TO 4,300 M
1991
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Carrying loads with springy poles
1991
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MAXIMUM BILATERAL CONTRACTIONS ARE MODIFIED BY NEURALLY MEDIATED INTERLIMB EFFECTS
1991
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The mechanics of running under simulated low gravity
1991
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INFLUENCE OF AGE AND EXERCISE TRAINING ON LIPID-METABOLISM IN FISCHER-344 RATS
1989
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INFLUENCE OF PLASMA-CATECHOLAMINES ON THE LACTATE THRESHOLD DURING GRADED-EXERCISE
1989
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ACUTE ANEMIA INCREASES LACTATE PRODUCTION AND DECREASES CLEARANCE DURING EXERCISE
1989
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ANESTHETIC EFFECTS ON LIVER AND MUSCLE GLYCOGEN CONCENTRATIONS - REST AND POSTEXERCISE
1989
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SYMPATHETIC RESPONSE TO EXERCISE IN VARIOUS TISSUES WITH ADVANCING AGE
1989
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CARDIAC ADAPTATIONS TO ENDURANCE TRAINING IN RATS WITH A CHRONIC MYOCARDIAL-INFARCTION
1989
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A Treadmill-Mounted Force Platform
1989
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DETERMINANTS OF VO2MAX IN RATS AFTER HIGH-INTENSITY SPRINT TRAINING
1989
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SYMPATHETIC ACTIVATION IS ASSOCIATED WITH INCREASES IN EMG DURING FATIGUING EXERCISE
1989
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COEXISTENCE OF TWITCH POTENTIATION AND TETANIC FORCE DECLINE IN RAT HINDLIMB MUSCLE
1988
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EFFECT OF AORTIC ARTERIAL CATHETERIZATION ON TISSUE GLYCOGEN-CONTENT
1988
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MEASUREMENTS OF METABOLIC-RATE IN RATS - A COMPARISON OF TECHNIQUES
1988
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GLYCOGEN CONCENTRATIONS AND ENDURANCE CAPACITY OF RATS WITH CHRONIC HEART-FAILURE
1988
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EFFECT OF TRAINING DETRAINING ON SUBMAXIMAL EXERCISE RESPONSES IN HUMANS
1987
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COMPLEXITY OF LACTATE KINETICS - REPLY
1986
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Delayed onset muscle soreness following repeated bouts of downhill running.
1985
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ADAPTIVE RESPONSE OF HYPERTROPHIED SKELETAL-MUSCLE TO ENDURANCE TRAINING
1985
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DYNAMIC EXERCISE TRAINING IN FOXHOUNDS .2. ANALYSIS OF SKELETAL-MUSCLE
1985
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FIBER NUMBER AND SIZE IN OVERLOADED CHICKEN ANTERIOR LATISSIMUS DORSI MUSCLE
1983
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ACUTE FASTING AND FIBER NUMBER IN RAT SOLEUS MUSCLE
1982
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EFFECT OF TRAINING ON BETA-ADRENERGIC-RECEPTOR NUMBER IN RAT-HEART
1982
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MUSCULAR ENLARGEMENT AND NUMBER OF FIBERS IN SKELETAL-MUSCLES OF RATS
1981
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Effect of hyperoxia on oxygen consumption in exercising ponies.
1979
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Effects of prosthetic stiffness and added mass on metabolic power and asymmetry in female runners with a leg amputation.
2024
Research
keywords
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06 Biological Sciences, 11 Medical and Health Sciences