DNA Polymerase III PubMed MeSh Term

Overview

subject area of

• A DNA polymerase III holoenzyme-like subassembly from an extreme thermophilic eubacterium.  Journal Article
• A bipartite polymerase-processivity factor interaction: only the internal beta binding site of the alpha subunit is required for processive replication by the DNA polymerase III holoenzyme.  Journal Article
• A novel assembly mechanism for the DNA polymerase III holoenzyme DnaX complex: association of deltadelta' with DnaX(4) forms DnaX(3)deltadelta'.  Journal Article
• A three-domain structure for the delta subunit of the DNA polymerase III holoenzyme delta domain III binds delta' and assembles into the DnaX complex.  Journal Article
• ACYCLIC GUANOSINE ANALOGS INHIBIT DNA POLYMERASE-ALPHA, POLYMERASE-DELTA, POLYMERASE-EPSILON WITH VERY DIFFERENT POTENCIES AND HAVE UNIQUE MECHANISMS OF ACTION  Journal Article
• Adenosine 5'-O-(3-thiotriphosphate) can support the formation of an initiation complex between the DNA polymerase III holoenzyme and primed DNA.  Journal Article
• Assembly of DNA polymerase III holoenzyme: co-assembly of gamma and tau is inhibited by DnaX complex accessory proteins but stimulated by DNA polymerase III core.  Journal Article
• Bacterial replicases and related polymerases  Journal Article
• Bacteriophage SPP1 DNA replication strategies promote viral and disable host replication in vitro  Journal Article
• Biotin tagging deletion analysis of domain limits involved in protein-macromolecular interactions. Mapping the tau binding domain of the DNA polymerase III alpha subunit.  Journal Article
• Breaking the rules: bacteria that use several DNA polymerase IIIs  Journal Article
• Carboxyl-terminal domain III of the delta' subunit of DNA polymerase III holoenzyme binds DnaX and supports cooperative DnaX complex assembly.  Journal Article
• Carboxyl-terminal domain III of the delta' subunit of the DNA polymerase III holoenzyme binds delta.  Journal Article
• Chaperoning of a Replicative Polymerase onto a Newly Assembled DNA-Bound Sliding Clamp by the Clamp Loader  Journal Article
• Characterization of 2'(3')-trinitrophenyl-ATP as an inhibitor of ATP-dependent initiation complex formation between the DNA polymerase III holoenzyme and primed DNA.  Journal Article
• Characterization of the unique C terminus of the Escherichia coli tau DnaX protein. Monomeric C-tau binds alpha AND DnaB and can partially replace tau in reconstituted replication forks.  Journal Article
• Chemical characterization and purification of the beta subunit of the DNA polymerase III holoenzyme from an overproducing strain.  Journal Article
• Chromosomal replicases as asymmetric dimers: studies of subunit arrangement and functional consequences.  Journal Article
• Cloning and identification of the product of the dnaE gene of Escherichia coli.  Journal Article
• Coordinated leading- and lagging-strand synthesis at the Escherichia coli DNA replication fork. IV. Reconstitution of an asymmetric, dimeric DNA polymerase III holoenzyme.  Journal Article
• Coupling of a replicative polymerase and helicase: a tau-DnaB interaction mediates rapid replication fork movement.  Journal Article
• Cycling of the E. coli lagging strand polymerase is triggered exclusively by the availability of a new primer at the replication fork  Journal Article
• DNA Polymerase alpha Subunit Residues and Interactions Required for Efficient Initiation Complex Formation Identified by a Genetic Selection  Journal Article
• DNA Replicases from a Bacterial Perspective  Journal Article
• DNA polymerase III holoenzyme from Thermus thermophilus identification, expression, purification of components, and use to reconstitute a processive replicase.  Journal Article
• DNA polymerase III holoenzyme of Escherichia coli.  Journal Article
• DNA polymerase III holoenzyme of Escherichia coli: an asymmetric dimeric replicative complex containing distinguishable leading and lagging strand polymerases.  Journal Article
• DNA polymerase III holoenzyme of Escherichia coli: components and function of a true replicative complex.  Journal Article
• DNA polymerase III holoenzyme. Components, structure, and mechanism of a true replicative complex.  Journal Article
• DNA polymerase III of Escherichia coli. Purification and identification of subunits.  Journal Article
• Detection of an epitope, not required for polymerization, that is conserved between E.coli DNA polymerases I and III and bacteriophage T4 DNA polymerase.  Journal Article
• Determination of the precise location and orientation of the Escherichia coli dnaE gene.  Journal Article
• Dissociation of the DNA polymerase III holoenzyme beta 2 subunits is accompanied by conformational change at distal cysteines 333.  Journal Article
• DnaX complex of Escherichia coli DNA polymerase III holoenzyme. Central role of tau in initiation complex assembly and in determining the functional asymmetry of holoenzyme.  Journal Article
• DnaX complex of Escherichia coli DNA polymerase III holoenzyme. Physical characterization of the DnaX subunits and complexes.  Journal Article
• DnaX complex of Escherichia coli DNA polymerase III holoenzyme. The chi psi complex functions by increasing the affinity of tau and gamma for delta.delta' to a physiologically relevant range.  Journal Article
• Escherichia coli DNA polymerase II is stimulated by DNA polymerase III holoenzyme auxiliary subunits.  Journal Article
• Escherichia coli DNA polymerase III holoenzyme footprints three helical turns of its primer.  Journal Article
• Escherichia coli DNA polymerase III holoenzyme subunits alpha, beta, and gamma directly contact the primer-template.  Journal Article
• Excess beta subunit can bypass the ATP requirement for highly processive synthesis by the Escherichia coli DNA polymerase III holoenzyme.  Journal Article
• Fluorescence energy transfer between the primer and the beta subunit of the DNA polymerase III holoenzyme.  Journal Article
• Glutamate overcomes the salt inhibition of DNA polymerase III holoenzyme.  Journal Article
• Identification of the acidic residues in the active site of DNA polymerase III.  Journal Article
• Identification of the beta-binding domain of the alpha subunit of Escherichia coli polymerase III holoenzyme.  Journal Article
• Identification, isolation, and characterization of the structural gene encoding the delta' subunit of Escherichia coli DNA polymerase III holoenzyme.  Journal Article
• Identification, isolation, and overexpression of the gene encoding the psi subunit of DNA polymerase III holoenzyme.  Journal Article
• Identification, molecular cloning and characterization of the gene encoding the chi subunit of DNA polymerase III holoenzyme of Escherichia coli.  Journal Article
• In vivo assembly of overproduced DNA polymerase III. Overproduction, purification, and characterization of the alpha, alpha-epsilon, and alpha-epsilon-theta subunits.  Journal Article
• Isolation, sequencing and overexpression of the gene encoding the theta subunit of DNA polymerase III holoenzyme.  Journal Article
• Localization of the active site of the alpha subunit of the Escherichia coli DNA polymerase III holoenzyme.  Journal Article
• Mismatch extension by Escherichia coli DNA polymerase III holoenzyme.  Journal Article
• Molecular cloning, sequencing, and overexpression of the structural gene encoding the delta subunit of Escherichia coli DNA polymerase III holoenzyme.  Journal Article
• Monoclonal antibodies specific for the alpha subunit of the Escherichia coli DNA polymerase III holoenzyme.  Journal Article
• Monoclonal antibodies specific for the tau subunit of the DNA polymerase III holoenzyme of Escherichia coli. Use to demonstrate that tau is the product of the dnaZX gene and that both it and gamma, the dnaZ gene product, are integral components of the same enzyme assembly.  Journal Article
• Only One ATP-binding DnaX Subunit Is Required for Initiation Complex Formation by the Escherichia coli DNA Polymerase III Holoenzyme  Journal Article
• Polymerase Chaperoning and Multiple ATPase Sites Enable the E. coli DNA Polymerase III Holoenzyme to Rapidly Form Initiation Complexes  Journal Article
• Proofreading activity of DNA polymerase III responds like elongation activity to auxiliary subunits.  Journal Article
• Properties of initiation complexes formed between Escherichia coli DNA polymerase III holoenzyme and primed DNA in the absence of ATP.  Journal Article
• Purification and characterization of DNA polymerase III'. Identification of tau as a subunit of the DNA polymerase III holoenzyme.  Journal Article
• Purification and characterization of the beta subunit of the DNA polymerase III holoenzyme of Escherichia coli.  Journal Article
• Purification of Escherichia coli DNA polymerase III holoenzyme.  Journal Article
• Quinazolin-2-ylamino-quinazolin-4-ols as novel non-nucleoside inhibitors of bacterial DNA polymerase III  Journal Article
• Reconstitution of a minimal DNA replicase from Pseudomonas aeruginosa and stimulation by non-cognate auxiliary factors.  Journal Article
• Reconstitution of the B-subtilis Replisome with 13 Proteins Including Two Distinct Replicases  Journal Article
• Reduction of the potent DNA polymerase III holoenzyme 3'----5' exonuclease activity by template-primer analogues.  Journal Article
• Role of the core DNA polymerase III subunits at the replication fork. Alpha is the only subunit required for processive replication.  Journal Article
• Sequence analysis of the Escherichia coli dnaE gene.  Journal Article
• Sequence analysis of the Escherichia coli dnaE gene.  Journal Article
• Site-specific pausing of deoxyribonucleic acid synthesis catalyzed by four forms of Escherichia coli DNA polymerase III.  Journal Article
• Size classes of products synthesized processively by DNA polymerase III and DNA polymerase III holoenzyme of Escherichia coli.  Journal Article
• Size classes of products synthesized processively by two subassemblies of Escherichia coli DNA polymerase III holoenzyme.  Journal Article
• Strand Displacement by DNA Polymerase III Occurs through a τ-ψ-χ Link to Single-stranded DNA-binding Protein Coating the Lagging Strand Template  Journal Article
• Tau binds and organizes Escherichia coli replication proteins through distinct domains. Domain III, shared by gamma and tau, binds delta delta ' and chi psi.  Journal Article
• Tau protects beta in the leading-strand polymerase complex at the replication fork.  Journal Article
• The DNA polymerase III holoenzyme: an asymmetric dimeric replicative complex with leading and lagging strand polymerases.  Journal Article
• The DnaX-binding subunits delta' and psi are bound to gamma and not tau in the DNA polymerase III holoenzyme.  Journal Article
• The Rate of Polymerase Release upon Filling the Gap between Okazaki Fragments Is Inadequate to Support Cycling during Lagging Strand Synthesis  Journal Article
• The adjacent dnaZ and dnaX genes of Escherichia coli are contained within one continuous open reading frame.  Journal Article
• The asymmetric dimeric polymerase hypothesis: a progress report.  Journal Article
• The base substitution and frameshift fidelity of Escherichia coli DNA polymerase III holoenzyme in vitro.  Journal Article
• The beta subunit of the DNA polymerase III holoenzyme becomes inaccessible to antibody after formation of an initiation complex with primed DNA.  Journal Article
• The beta subunit of the Escherichia coli DNA polymerase III holoenzyme interacts functionally with the catalytic core in the absence of other subunits.  Journal Article
• The chi psi subunits of DNA polymerase III holoenzyme bind to single-stranded DNA-binding protein (SSB) and facilitate replication of an SSB-coated template.  Journal Article
• The delta and delta ' subunits of the DNA polymerase III holoenzyme are essential for initiation complex formation and processive elongation.  Journal Article
• The dimer of the beta subunit of Escherichia coli DNA polymerase III holoenzyme is dissociated into monomers upon binding magnesium(II).  Journal Article
• The gamma subunit of DNA polymerase III holoenzyme of Escherichia coli is produced by ribosomal frameshifting.  Journal Article
• Transcriptional organization of the Escherichia coli dnaX gene.  Journal Article
• tau binds and organizes Escherichia coli replication proteins through distinct domains. Domain IV, located within the unique C terminus of tau, binds the replication fork, helicase, DnaB.  Journal Article
• tau binds and organizes Escherichia coli replication proteins through distinct domains: domain III, shared by gamma and tau, oligomerizes DnaX.  Journal Article
• tau binds and organizes Escherichia coli replication through distinct domains. Partial proteolysis of terminally tagged tau to determine candidate domains and to assign domain V as the alpha binding domain.  Journal Article
• tau couples the leading- and lagging-strand polymerases at the Escherichia coli DNA replication fork.  Journal Article

broader concept

• DNA-Directed DNA Polymerase  PubMed MeSh Term