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Publications in VIVO
 

Han, Min Professor and Howard Hughes Medical Institute Investigator

Positions

Research Areas research areas

Research

research overview

  • Han lab has engaged in dynamic research programs addressing important biological problems related to human diseases, primarily using C. elegans and mouse. The lab always aims for important questions in relatively unexplored areas and encourages researchers to generate their own ideas. In the early 90s, the lab focused on identifying key regulators of the RTK-RAS-MAP kinase signaling, and then extended efforts to tackling genetic redundancy. In the late 90s, some researchers moved to study cellular/morphogenesis events during development, including discovering the SUN-KASH NE complexes and their functions. The lab has also made breakthrough advances in studying the functions of miRNAs and non-canonic caspase activities using systematic methods. In recent years, the lab discovered four novel nutrient sensing mechanisms that regulate development, reproductivity and behavior in response to changes in fatty acids and nucleotide variants. We are also exploring nutrients from gut microbes.

keywords

  • Functions of lipids, lipid metabolism and small RNAs in animal development and behaviors under various physiological conditions, Stress responses, starvation responses, Nucleotide metabolism, C elegans and mouse genetics, nuclear envelope complexes, nutrient response, metabolism, environmental sex determination, nucleotide sensing, non-canonic function of caspases, impact of gut of microbes on animal physiology, iron uptake

Publications

selected publications

Teaching

courses taught

  • MCDB 4425 Topics in Membrane Biology: Cell Biology, Physiology and Disease (Spring 2019)
  • MCDB 5220 Molecular Genetics (Methods and Logic) (Spring 2019)
  • MCDB 5425 Topics in Membrane Biology: Cell Biology, Physiology and Disease (Spring 2019)
  • MCDB 6000 Introduction to Laboratory Methods (Spring 2019)
  • MCDB 8990 Doctoral Dissertation (Spring 2019)
  • MCDB 4840 Upper-Division Independent Study (Fall 2018)
  • MCDB 6000 Introduction to Laboratory Methods (Fall 2018)
  • MCDB 8990 Doctoral Dissertation (Fall 2018)
  • MCDB 4840 Upper-Division Independent Study (Summer 2018)
  • MCDB 8990 Doctoral Dissertation (Summer 2018)
  • MCDB 6000 Introduction to Laboratory Methods (Spring 2018)
  • MCDB 8990 Doctoral Dissertation (Spring 2018)

Background

International Activities

global connections related to teaching and scholarly work (in recent years)

Other Profiles