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Publications in VIVO

Ahn, Natalie

Distinguished Professor

Positions

Research Areas research areas

Research

research overview

  • Research Interests: Signal transduction pathways in melanoma, MAP kinase pathways and mechanisms of response to targeted therapeutics against BRaf, MAPKK, and MAP kinases, and drug resistance in cancer cells. Control of cancer cell polarity and migration by Wnt5a pathway signaling. Analysis of protein kinase regulation with studies of protein dynamics by hydrogen exchange mass spectrometry, NMR, enzyme kinetics and site directed mutagenesis. Analysis of signaling responses by functional proteomics, and methods development for proteomics and mass spectrometry.

keywords

  • Signal transduction pathways in cancer, Melanoma mechanisms of drug resistance, Functional proteomics, mass spectrometry, bioanalytical studies of proteins, protein chemistry

Publications

selected publications

Teaching

courses taught

  • BCHM 4720 - Metabolic Pathways and Human Disease
    Primary Instructor - Spring 2023 / Spring 2024
    Covers energy metabolism and anabolic/catabolic pathways; metabolism of carbohydrates, lipids, amino acids, and nucleic acids; photosynthesis; special topics on human diseases with pathologies and metabolic pathways. Formerly CHEM 4720. Same as BCHM 5720.
  • BCHM 6901 - Research in Biochemistry
    Primary Instructor - Fall 2021 / Spring 2022 / Fall 2022 / Spring 2023
    May be repeated up to 15 total credit hours.
  • CHEM 1400 - Foundations of Chemistry
    Primary Instructor - Fall 2019 / Fall 2020 / Fall 2021
    Covers core concepts in chemistry: nature of matter (atomic and molecular structure, bonding and macroscopic properties), transformations of matter (chemical reactivity), and quantifying chemical transformations (thermochemistry, thermodynamics and kinetics). Emphasizes critical thinking and cultivate core problem solving skills utilized by scientists. Intended for first semester CHEM/BCHM majors. Department enforced prerequisites: one year high school chemistry or CHEM 1021 (minimum grad C-) and high school math through pre-calculus. Not recommended for students with grades below B- in CHEM 1021. Department enforced corequisite: CHEM 1401. Degree credit not granted for this course and CHEM 1113.
  • CHEM 4761 - Biochemistry Laboratory
    Primary Instructor - Fall 2018
    Two 4-hour periods per week. Introduction to modern biochemical techniques. Topics include enzymology, spectrophotometry, electrophoresis, multi-step protein purification, recombinant DNA techniques and molecular cloning. Formerly CHEM 4761.
  • CHEM 6901 - Research in Chemistry
    Primary Instructor - Spring 2018 / Fall 2018
    May be repeated up to 15 total credit hours.

Background

awards and honors

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