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Lowry, Christopher A. Associate Professor

Positions

Research Areas research areas

Research

research overview

  • Dr. Lowry’s research is focused on mechanisms underlying stress-related physiology and behavior, with a focus on the role of serotonergic systems. Current projects address four main topics: 1) the integrative (molecular to organismal) biological mechanisms controlling anxiety-related physiological responses, anxiety-related behavior, and anxiety states, including the role of the microbiome; 2) mechanisms underlying physiologic and behavioral responses to thermal stimuli, and the potential for whole-body infrared heating (WBH) for treatment of major depressive disorder (MDD); 3) mechanisms underlying rapid negative feedback control of the hypothalamic-pituitary-adrenal (HPA) axis, including a potential role for the corticosterone-sensitive organic cation transporter 3 (OCT3); 4) mechanisms underlying physiologic and behavioral responses to peripheral immune activation, and the potential for immunoregulation in prevention and treatment of stress-related psychiatric disorders

keywords

  • behavioral neuroendocrinology, behavioral neuroscience, psychoneuroimmunology, stress physiology, stress-related pathology, serotonergic systems

Publications

selected publications

Teaching

courses taught

  • IPHY 1181 - Biological Probiotic/Drug Discovery Through Hands-on Screens
    Primary Instructor - Spring 2019 / Fall 2019
    Provides introduction to research and laboratory experience. Students will work in teams to screen novel mycobacterial strains for use as probiotics or immunoregulatory/anti-inflammatory drugs using THP-1 cells, a human monocytic cell line. Topics covered include the hygiene or Old Friends hypothesis, the human microbiome, approaches to screening for new probiotics of therapeutics and statistical analysis of the data. Same as MCDB 1181.
  • IPHY 4440 - Endocrinology
    Primary Instructor - Spring 2020
    Introduces mammalian endocrine system. Provides a thorough analysis of chemical communication by hormones and related bioregulators with emphasis on the major endocrine systems such as the thyroid, gonad, pituitary and the brain. Students must take lecture and recitation sections. Same as IPHY 5440.
  • IPHY 4930 - Internship
    Primary Instructor - Spring 2018
    Provides an opportunity for field/laboratory work in a variety of different settings. Consult with faculty for approval. May be repeated up to 6 total credit hours. Department enforced prerequisite: completion of at least two of the major core classes.
  • IPHY 6840 - Research Project
    Primary Instructor - Spring 2018 / Fall 2019 / Fall 2020 / Spring 2021
    Involves a scholarly investigation of a selected topic using literature and/or experimental techniques. Advisor required. May be repeated up to 3 total credit hours.
  • MCDB 1181 - Biological Probiotic/Drug Discovery Through Hands-on Screens
    Primary Instructor - Spring 2019 / Fall 2019
    Provides introduction to research and laboratory experience. Students will work in teams to screen novel mycobacterial strains for use as probiotics or immunoregulatory/anti-inflammatory drugs using THP-1 cells, a human monocytic cell line. Topics covered include the hygiene or Old Friends hypothesis, the human microbiome, approaches to screening for new probiotics of therapeutics and statistical analysis of the data. Same as IPHY 1181.
  • MCDB 4980 - Honors Research
    Primary Instructor - Spring 2020
    Provides faculty-supervised research for students who have been approved by the departmental honors committee. Normally taken during the semester before completion of the honors thesis. Recommended prerequisite: MCDB 4840 or comparable research experience, and minimum GPA of 3.20.
  • MCDB 4990 - Honors Thesis
    Primary Instructor - Spring 2020
    Involves the preparation and defense of an honors thesis, based on faculty-supervised original research, including final phases of the research project. Recommended prerequisites: MCDB 4840 or MCDB 4980 or comparable research experience, and minimum GPA of 3.3 and approval by the MCDB Honors Committee.

Background

International Activities

global connections related to teaching and scholarly work (in recent years)

Other Profiles