publication venue for

• Antibodies blocking PlGF or VEGF interactions with the NRP1 receptor mediate antiproliferative effects 2026
• Cleavage of histone H2A during embryonic stem cell differentiation destabilizes nucleosomes to counteract gene activation 2026
• Missense mutations in intrinsically disordered protein regions link pathogenicity and phase separation 2025
• Polyserine-tau interactions modulate tau fibrillization 2025
• Systematic characterization of zinc in a series of breast cancer cell lines reveals significant changes in zinc homeostasis 2025
• PKM splice-switching ASOs induce upregulation of dual-specificity phosphatases and dephosphorylation of ERK1/2 in hepatocellular carcinoma 2025
• Enterobactin carries iron into Caenorhabditis elegans and mammalian intestinal cells by a mechanism independent of divalent metal transporter DMT1 2025
• Phosphorylation regulates the chromatin remodeler SMARCAD1 in nucleosome binding, ATP hydrolysis, and histone exchange 2024
• Analysis of Poly(ethylene terephthalate) degradation kinetics of evolved IsPETase variants using a surface crowding model 2024
• The PARN, TOE1, and USB1 RNA deadenylases and their roles in RNA 2023
• Distinct effects of two hearing loss-associated mutations in the sarcomeric myosin MYH7b 2023
• The penultimate step of proteasomal ATPase assembly is mediated by a switch dependent on the chaperone Nas2 2023
• Functional divergence of the sarcomeric myosin, MYH7b, supports species-specific biological roles 2023
• Intrinsically disordered regions that drive phase separation form a robustly distinct protein class 2023
• Systematic mutagenesis of TFIIH subunit p52/Tfb2 identifies residues required for XPB/Ssl2 subunit function and genetic interactions with TFB6 2022
• Manganese promotes α-synuclein amyloid aggregation through the induction of protein phase transition 2022
• Beta turn propensity and a model polymer scaling exponent identify intrinsically disordered phase-separating proteins 2021
• Deconvolution of multiplexed transcriptional responses to wood smoke particles defines rapid aryl hydrocarbon receptor signaling dynamics 2021
• Calcium-dependent and -independent lipid transfer mediated by tricalbins in yeast 2021
• Defective insulin receptor signaling in hPSCs skews pluripotency and negatively perturbs neural differentiation 2021
• Global proteomics of Ubqln2-based murine models of ALS 2021
• Myosin 7b is a regulatory long noncoding RNA (lncMYH7b) in the human heart 2021
• RNase L promotes the formation of unique ribonucleoprotein granules distinct from stress granules 2020
• Inducible Exoc7/Exo70 knockout reveals a critical role of the exocyst in insulin-regulated GLUT4 exocytosis 2019
• Myosin motor domains carrying mutations implicated in early or late onset hypertrophic cardiomyopathy have similar properties 2019
• The ATPase cycle of human muscle myosin II isoforms: Adaptation of a single mechanochemical cycle for different physiological roles 2019
• The plant triterpenoid celastrol blocks PINK1-dependent mitophagy by disrupting PINK1's association with the mitochondrial protein TOM20 2019
• 15-Deoxy-^12,14-prostaglandin J2 promotes phosphorylation of eukaryotic initiation factor 2 and activates the integrated stress response 2019
• Two alternative mechanisms regulate the onset of chaperone-mediated assembly of the proteasomal ATPases 2019
• The N-peptide-binding mode is critical to Munc18-1 function in synaptic exocytosis 2018
• Interleukin-37 treatment of mice with metabolic syndrome improves insulin sensitivity and reduces pro-inflammatory cytokine production in adipose tissue 2018
• The complex structure and function of Mediator 2018
• Dilated cardiomyopathy myosin mutants have reduced force-generating capacity 2018
• Sorafenib targets the mitochondrial electron transport chain complexes and ATP synthase to activate the PINK1-Parkin pathway and modulate cellular drug response 2017
• Cobalamin riboswitches exhibit a broad range of ability to discriminate between methylcobalamin and adenosylcobalamin 2017
• The Most Prevalent Freeman-Sheldon Syndrome Mutations in the Embryonic Myosin Motor Share Functional Defects 2016
• Developmental Defects of Caenorhabditis elegans Lacking Branched-chain α-Ketoacid Dehydrogenase Are Mainly Caused by Monomethyl Branched-chain Fatty Acid Deficiency 2016
• Rapid Fine Conformational Epitope Mapping Using Comprehensive Mutagenesis and Deep Sequencing 2015
• Producing Glucose 6-Phosphate from Cellulosic Biomass 2015
• Histone Core Phosphorylation Regulates DNA Accessibility 2015
• DNA Polymerase alpha Subunit Residues and Interactions Required for Efficient Initiation Complex Formation Identified by a Genetic Selection 2015
• Identification of Subunit Binding Positions on a Model Fork and Displacements That Occur during Sequential Assembly of the Escherichia coli Primosome 2015
• Structure-guided Mutational Analysis of Gene Regulation by the Bacillus subtilis pbuE Adenine-responsive Riboswitch in a Cellular Context 2015
• Crystal Structure of BamB Bound to a Periplasmic Domain Fragment of BamA, the Central Component of the β-Barrel Assembly Machine 2015
• Syntaxin 8 Regulates Platelet Dense Granule Secretion, Aggregation, and Thrombus Stability 2015
• Role of Glucose Metabolism and ATP in Maintaining PINK1 Levels during Parkin-mediated Mitochondrial Damage Responses 2015
• The N- and C-terminal Domains of Tomosyn Play Distinct Roles in Soluble N-Ethylmaleimide-sensitive Factor Attachment Protein Receptor Binding and Fusion Regulation 2014
• The p38β Mitogen-activated Protein Kinase Possesses an Intrinsic Autophosphorylation Activity, Generated by a Short Region Composed of the α-G Helix and MAPK Insert 2014
• The Hypertrophic Cardiomyopathy Myosin Mutation R453C Alters ATP Binding and Hydrolysis of Human Cardiac β- Myosin* 2014
• Programmed Cell Death Protein 5 Interacts with the Cytosolic Chaperonin Containing Tailless Complex Polypeptide 1 (CCT) to Regulate β-Tubulin Folding 2014
• Identification of Global Ferredoxin Interaction Networks in Chlamydomonas reinhardtii 2013
• RhoG Protein Regulates Platelet Granule Secretion and Thrombus Formation in Mice 2013
• Inhibition of Telomerase Recruitment and Cancer Cell Death 2013
• The Superfast Human Extraocular Myosin Is Kinetically Distinct from the Fast Skeletal IIa, IIb, and IId Isoforms 2013
• Synip Arrests Soluble N-Ethylmaleimide-sensitive Factor Attachment Protein Receptor (SNARE)-dependent Membrane Fusion as a Selective Target Membrane SNARE-binding Inhibitor 2013
• The PriA Replication Restart Protein Blocks Replicase Access Prior to Helicase Assembly and Directs Template Specificity through Its ATPase Activity 2013
• The Chemical Synthesis of DNA/RNA: Our Gift to Science 2013
• Genetic Analysis of the Hox Hydrogenase in the Cyanobacterium Synechocystis sp PCC 6803 Reveals Subunit Roles in Association, Assembly, Maturation, and Function 2012
• Human Pumilio Proteins Recruit Multiple Deadenylases to Efficiently Repress Messenger RNAs 2012
• Alternative Modes of Binding of Poly(ADP-ribose) Polymerase 1 to Free DNA and Nucleosomes 2012
• Product Binding Varies Dramatically between Processive and Nonprocessive Cellulase Enzymes 2012
• Structural Insights into Apoptotic DNA Degradation by CED-3 Protease Suppressor-6 (CPS-6) from Caenorhabditis elegans 2012
• Histidine 66 in Escherichia coli elongation factor tu selectively stabilizes aminoacyl-tRNAs. 2012
• Toward a Systems Biology Perspective on Enzyme Evolution 2012
• Endosomal Na+ (K+)/H+ Exchanger Nhx1/Vps44 Functions Independently and Downstream of Multivesicular Body Formation 2011
• Histone Chaperone FACT Coordinates Nucleosome Interaction through Multiple Synergistic Binding Events 2011
• Structural Defects in the Regulatory Particle-Core Particle Interface of the Proteasome Induce a Novel Proteasome Stress Response 2011
• The Linker Region of MacroH2A Promotes Self-association of Nucleosomal Arrays 2011
• MicroRNA-378 Targets the Myogenic Repressor MyoR during Myoblast Differentiation 2011
• The Histone Chaperone FACT: Structural Insights and Mechanisms for Nucleosome Reorganization 2011
• Probing Carbohydrate Product Expulsion from a Processive Cellulase with Multiple Absolute Binding Free Energy Methods 2011
• Cellular Abundance of Mps1 and the Role of Its Carboxyl Terminal Tail in Substrate Recruitment 2010
• Only One ATP-binding DnaX Subunit Is Required for Initiation Complex Formation by the Escherichia coli DNA Polymerase III Holoenzyme 2010
• Disruption of Lysosome Function Promotes Tumor Growth and Metastasis in Drosophila 2010
• Strand Displacement by DNA Polymerase III Occurs through a τ-ψ-χ Link to Single-stranded DNA-binding Protein Coating the Lagging Strand Template 2009
• Genetically Encoded Sensors to Elucidate Spatial Distribution of Cellular Zinc 2009
• Analysis of a Critical Interaction within the Archaeal Box C/D Small Ribonucleoprotein Complex 2009
• Budding Yeast Centrosome Duplication Requires Stabilization of Spc29 via Mps1-mediated Phosphorylation 2009
• TATA-binding Protein and Transcription Factor IIB Induce Transcript Slipping during Early Transcription by RNA Polymerase II 2009
• Initiation of New DNA Strands by the Herpes Simplex Virus-1 Primase-Helicase Complex and Either Herpes DNA Polymerase or Human DNA Polymerase α 2009
• Isolation of Intrinsically Active (MEK-independent) Variants of the ERK Family of Mitogen-activated Protein (MAP) Kinases 2008
• A Thermodynamic Model for Nap1-Histone Interactions 2008
• The Cth2 ARE-binding Protein Recruits the Dhh1 Helicase to Promote the Decay of Succinate Dehydrogenase SDH4 mRNA in Response to Iron Deficiency 2008
• Crystal structure of the lysine riboswitch regulatory mRNA element 2008
• The reticulon and DP1/Yop1p proteins form immobile oligomers in the tubular endoplasmic reticulum 2008
• BI-1 Regulates Endoplasmic Reticulum Ca2+ Homeostasis Downstream of Bcl-2 Family Proteins 2008
• Suppression of in vivo β-amyloid peptide toxicity by overexpression of the HSP-16.2 small chaperone protein 2008
• Mps1 activation loop autophosphorylation enhances kinase activity 2007
• Activation of Mps1 promotes transforming growth factor-β-independent Smad signaling 2007
• alpha-7 Nicotinic receptor gene promoter polymorphisms in inbred mice affect expression in a cell type-specific fashion 2007
• The histone variant macro-H2A preferentially forms "hybrid nucleosomes" 2006
• Global gene expression analysis of ERK5 and ERK1/2 signaling reveals a role for HIF-1 in ERK5-mediated responses 2006
• Sodium butyrate ameliorates histone hypoacetylation and neurodegenerative phenotypes in a mouse model for DRPLA 2006
• The NH2-terminal php domain of the alpha subunit of the Escherichia coli replicase binds the epsilon proofreading subunit. 2006
• RNA aptamers targeting the cell death inhibitor CED-9 induce cell killing in Caenorhabditis elegans 2006
• Conversion of green fluorescent protein into a toxic, aggregation-prone protein by C-terminal addition of a short peptide 2006
• Discovery and characterization of the cryptic psi subunit of the pseudomonad DNA replicase. 2005
• The sequence at specific positions in the early transcribed region sets the rate of transcript synthesis by RNA polymerase II in vitro 2005
• YxiN is a modular protein combining a DEx(D/H) core and a specific RNA-binding domain. 2005
• The core histone n-terminal tail domains function independently and additively during salt-dependent oligomerization of nucleosomal arrays 2005
• POT1 stimulates RecQ helicases WRN and BLM to unwind telomeric DNA substrates 2005
• Ubiquitination of p27^Kip1 requires physical interaction with cyclin E and probable phosphate recognition by SKP2 2005
• Switching human telomerase on and off with hPOT1 protein in vitro 2005
• Myocyte enhancer factor-2 and serum response factor binding elements regulate fast myosin heavy chain transcription in vivo 2005
• Reconstitution of a minimal DNA replicase from Pseudomonas aeruginosa and stimulation by non-cognate auxiliary factors. 2005
• Yeast flavohemoglobin, a nitric oxide oxidoreductase, is located in both the cytosol and the mitochondrial matrix 2005
• Expression of a RecQ helicase homolog affects progression through crisis in fission yeast lacking telomerase 2005
• A role for Pet100p in the assembly of yeast cytochrome c oxidase - Interaction with a subassembly that accumulates in a pet100 mutant 2005
• Nucleosome assembly protein 1 exchanges histone H2A-H2B dimers and assists nucleosome sliding 2005
• α-conotoxin BuIA, a novel peptide from Conus bullatus, distinguishes among neuronal nicotinic acetylcholine receptors 2005
• Mitochondrial protein oxidation in yeast mutants lacking manganese- (MnSOD) or copper- and zinc-containing superoxide dismutase (CuZnSOD) - Evidence that MnSOD and CuZnSOD have both unique and overlapping functions in protecting mitochondrial proteins from oxidative damage 2004
• Molecular and biochemical characterization of the Skp2-Cks1 binding interface 2004
• Dependence of site-2 protease cleavage of ATF6 on prior site-1 protease digestion is determined by the size of the luminal domain of ATF6 2004
• The basic leucine zipper domain of c-Jun functions in transcriptional activation through interaction with the N terminus of human TATA-binding protein-associated factor-1 (human TAF_II250) 2004
• A new fluorescence resonance energy transfer approach demonstrates that the histone variant H2AZ stabilizes the histone octamer within the nucleosome 2004
• A mechanism of oxygen sensing in yeast - Multiple oxygen-responsive steps in the heme biosynthetic pathway affect Hap1 activity 2003
• Preferential binding of the histone (H3-H4)₂ tetramer by NAP1 is mediated by the amino-terminal histone tails 2003
• A negatively charged amino acid in Skp2 is required for Skp2-Cks1 interaction and ubiquitination of p27(Kip1) 2003
• Yin Yang 1 is increased in human heart failure and represses the activity of the human α-myosin heavy chain promoter 2003
• Purification and mass spectrometric identification of GA-binding protein (GABP) as the functional pituitary Ets factor binding to the basal transcription element of the prolactin promoter 2003
• Congo red populates partially unfolded states of an amyloidogenic protein to enhance aggregation and amyloid fibril formation 2003
• Intracellular calcium and myosin isoform transitions - Calcineurin and calcium-calmodulin kinase pathways regulate preferential activation of the iia myosin heavy chain promoter 2002
• Exposure of yeast cells to anoxia induces transient oxidative stress - Implications for the induction of hypoxic genes 2002
• Kinetics and energetics of assembly, nucleation, and growth of aggregates and fibrils for an amyloidogenic protein - Insights into transition states from pressure, temperature, and co-solute studies 2002
• Phosphatase inhibition leads to histone deacetylases 1 and 2 phosphorylation and disruption of corepressor interactions 2002
• DNA polymerase III holoenzyme from Thermus thermophilus identification, expression, purification of components, and use to reconstitute a processive replicase. 2002
• A three-domain structure for the delta subunit of the DNA polymerase III holoenzyme delta domain III binds delta' and assembles into the DnaX complex. 2002
• The luminal domain of ATF6 senses endoplasmic reticulum (ER) stress and causes translocation of ATF6 from the ER to the Golgi 2002
• Global regulation of post-translational modifications on core histones 2002
• Phosphorylation of MEK1 by cdk5/p35 down-regulates the mitogen-activated protein kinase pathway 2002
• Carboxyl-terminal domain III of the delta' subunit of DNA polymerase III holoenzyme binds DnaX and supports cooperative DnaX complex assembly. 2001
• High pressure refolding of recombinant human growth hormone from insoluble aggregates - Structural transformations, kinetic barriers, and energetics 2001
• Constitutive activation of extracellular signal-regulated kinase 2 by synergistic point mutations 2001
• Peroxisome proliferator-activated receptor γ inhibits transforming growth factor β-induced connective tissue growth factor expression in human aortic smooth muscle cells by interfering with Smad3 2001
• Different pathways regulate expression of the skeletal myosin heavy chain genes 2001
• Carboxyl-terminal domain III of the delta' subunit of the DNA polymerase III holoenzyme binds delta. 2001
• A novel mechanism for regulating transforming growth factor β (TGF-β) signaling -: Functional modulation of type III TGF-β receptor expression through interaction with the PDZ domain protein, GIPC 2001
• tau binds and organizes Escherichia coli replication proteins through distinct domains: domain III, shared by gamma and tau, oligomerizes DnaX. 2001
• Assembly of DNA polymerase III holoenzyme: co-assembly of gamma and tau is inhibited by DnaX complex accessory proteins but stimulated by DNA polymerase III core. 2001
• The delta and delta ' subunits of the DNA polymerase III holoenzyme are essential for initiation complex formation and processive elongation. 2001
• c-Jun binds the N terminus of human TAF(II)250 to derepress RNA polymerase II transcription in vitro 2001
• Modulation of the G protein regulator phosducin by Ca²⁺/calmodulin-dependent protein kinase II phosphorylation and 14-3-3 protein binding 2001
• Yeast Mps1p phosphorylates the spindle pole component Spc110p in the N-terminal domain 2001
• Effects of anoxia and the mitochondrion on expression of aerobic nuclear COX genes in yeast - Evidence for a signaling pathway from the mitochondrial genome to the nucleus 2001
• Tau binds and organizes Escherichia coli replication proteins through distinct domains. Domain III, shared by gamma and tau, binds delta delta ' and chi psi. 2001
• tau binds and organizes Escherichia coli replication proteins through distinct domains. Domain IV, located within the unique C terminus of tau, binds the replication fork, helicase, DnaB. 2001
• tau binds and organizes Escherichia coli replication through distinct domains. Partial proteolysis of terminally tagged tau to determine candidate domains and to assign domain V as the alpha binding domain. 2001
• Counteracting effects of renal solutes on amyloid fibril formation by immunoglobulin light chains 2001
• A kinetic model for the early steps of RNA synthesis by human RNA polymerase II 2000
• The hexameric eukaryotic MCM helicase: Building symmetry from nonidentical parts 2000
• Entrapping intermediates of thermal aggregation in α-helical proteins with low concentration of guanidine hydrochloride 2000
• 3 '-azidothymidine potently inhibits the biosynthesis of highly branched N-linked oligosaccharides and poly-N-acetyllactosamine chains in cells 2000
• Activation of ATF6 and an ATF6 DNA binding site by the endoplasmic reticulum stress response 2000
• A mutant of Tetrahymena telomerase reverse transcriptase with increased processivity 2000
• Importin β mediates nuclear translocation of Smad 3 2000
• Cysteine-rich fibroblast growth factor receptor alters secretion and intracellular routing of fibroblast growth factor 3 2000
• Characterization of the unique C terminus of the Escherichia coli tau DnaX protein. Monomeric C-tau binds alpha AND DnaB and can partially replace tau in reconstituted replication forks. 2000
• The DnaX-binding subunits delta' and psi are bound to gamma and not tau in the DNA polymerase III holoenzyme. 2000
• Thermodynamic modulation of light chain amyloid fibril formation 2000
• Chaperone activity of a chimeric GroEL protein that can exist in a single or double ring form 1999
• Targeted Mutations in a Trametes villosa Laccase 1999
• Nuclear localization of mitogen-activated protein kinase kinase 1 (MKK1) is promoted by serum stimulation and G2-M progression - Requirement for phosphorylation at the activation lip and signaling downstream of MKK 1999
• Transforming growth factor-β induces formation of a dithiothreitol-resistant type I type II receptor complex in live cells 1999
• Mismatch extension by Escherichia coli DNA polymerase III holoenzyme. 1999
• Quantitative assessment of EF-1α•GTP binding to aminoacyl-tRNAs, aminoacyl-viral RNA, and tRNA shows close correspondence to the RNA binding properties of EF-Tu 1999
• Detection of a conserved α-helix in the kinase-docking region of the aspartate receptor by cysteine and disulfide scanning 1998
• The base substitution and frameshift fidelity of Escherichia coli DNA polymerase III holoenzyme in vitro. 1998
• The chi psi subunits of DNA polymerase III holoenzyme bind to single-stranded DNA-binding protein (SSB) and facilitate replication of an SSB-coated template. 1998
• Role of the core DNA polymerase III subunits at the replication fork. Alpha is the only subunit required for processive replication. 1998
• Feedback regulation of Raf-1 and mitogen-activated protein kinase (MAP) kinase kinases 1 and 2 by MAP kinase phosphatase-1 (MKP-1) 1998
• Independent folding and ligand specificity of the C2 calcium-dependent lipid binding domain of cytosolic phospholipase A₂ 1998
• Cysteine and disulfide scanning reveals a regulatory α-helix in the cytoplasmic domain of the aspartate receptor 1997
• Phosphorylation of I kappa B-alpha inhibits its cleavage by caspase CPP32 in vitro 1997
• Destabilization of peptide binding and interdomain communication by an E543K mutation in the bovine 70-kDa heat shock cognate protein, a molecular chaperone 1997
• Involvement of a specific metal ion in the transition of the hammerhead ribozyme to its catalytic conformation 1997
• Electron paramagnetic resonance studies of succinate:ubiquinone oxidoreductase from Paracoccus denitrificans - Evidence for a magnetic interaction between the 3Fe-4S cluster and cytochrome b 1997
• Effects of oxygen concentration on the expression of cytochrome c and cytochrome c oxidase genes in yeast 1997
• Single-stranded RNA recognition by the bacteriophage T4 translational repressor, RegA 1997
• Structural requirements for major histocompatibility complex class II invariant chain trafficking in polarized Madin-Darby canine kidney cells 1997
• Identification and characterization of a fibroblast growth factor (FGF) binding domain in the cysteine-rich FGF receptor 1997
• Mass spectrometric analysis of 40 S ribosomal proteins from rat-1 fibroblasts 1996
• Contributions of the Mitogen-activated Protein (MAP) Kinase Backbone and Phosphorylation Loop to MEK Specificity 1996
• Function and expression of flavohemoglobin in Saccharomyces cerevisiae - Evidence for a role in the oxidative stress response 1996
• G alpha 12 and G alpha 13 regulate extracellular signal-regulated kinase and c-Jun kinase pathways by different mechanisms in COS-7 cells 1996
• tau couples the leading- and lagging-strand polymerases at the Escherichia coli DNA replication fork. 1996
• Biotin tagging deletion analysis of domain limits involved in protein-macromolecular interactions. Mapping the tau binding domain of the DNA polymerase III alpha subunit. 1996
• Identification of the beta-binding domain of the alpha subunit of Escherichia coli polymerase III holoenzyme. 1996
• In vivo assembly of overproduced DNA polymerase III. Overproduction, purification, and characterization of the alpha, alpha-epsilon, and alpha-epsilon-theta subunits. 1996
• Cloning and characterization of PET100, a gene required for the assembly of yeast cytochrome c oxidase 1996
• In vivo assembly of the tau-complex of the DNA polymerase III holoenzyme expressed from a five-gene artificial operon. Cleavage of the tau-complex to form a mixed gamma-tau-complex by the OmpT protease. 1996
• Tau protects beta in the leading-strand polymerase complex at the replication fork. 1996
• Induction of mitogen-activated protein kinase phosphatase 1 by the stress-activated protein kinase signaling pathway but not by extracellular signal-regulated kinase in fibroblasts 1996
• DnaX complex of Escherichia coli DNA polymerase III holoenzyme. Central role of tau in initiation complex assembly and in determining the functional asymmetry of holoenzyme. 1995
• DnaX complex of Escherichia coli DNA polymerase III holoenzyme. Physical characterization of the DnaX subunits and complexes. 1995
• DnaX complex of Escherichia coli DNA polymerase III holoenzyme. The chi psi complex functions by increasing the affinity of tau and gamma for delta.delta' to a physiologically relevant range. 1995
• CONSERVATION OF LIGAND SPECIFICITY BETWEEN THE MAMMALIAN AND AMPHIBIAN FIBROBLAST GROWTH-FACTOR RECEPTORS 1995
• LOCK ON OFF DISULFIDES IDENTIFY THE TRANSMEMBRANE SIGNALING HELIX OF THE ASPARTATE RECEPTOR 1995
• 3'-AZIDOTHYMIDINE (ZIDOVUDINE) INHIBITS GLYCOSYLATION AND DRAMATICALLY ALTERS GLYCOSPHINGOLIPID SYNTHESIS IN WHOLE CELLS AT CLINICALLY RELEVANT CONCENTRATIONS 1995
• OLIGONUCLEOTIDES AS RESEARCH, DIAGNOSTIC, AND THERAPEUTIC AGENTS 1995
• Escherichia coli DNA polymerase III holoenzyme subunits alpha, beta, and gamma directly contact the primer-template. 1995
• ISOFORMS OF YEAST CYTOCHROME-C-OXIDASE SUBUNIT-V AFFECT THE BINUCLEAR REACTION-CENTER AND AFTER THE KINETICS OF INTERACTION WITH THE ISOFORMS OF YEAST CYTOCHROME-C 1995
• Escherichia coli DNA polymerase III holoenzyme footprints three helical turns of its primer. 1994
• Human immunodeficiency virus nucleocapsid protein accelerates strand transfer of the terminally redundant sequences involved in reverse transcription. 1994
• THE BACTERIOPHAGE-T4 REGB RIBONUCLEASE - STIMULATION OF THE PURIFIED ENZYME BY RIBOSOMAL-PROTEIN-S1 1994
• MISINCORPORATION OF NUCLEOTIDES BY CALF THYMUS DNA PRIMASE AND ELONGATION OF PRIMERS CONTAINING MULTIPLE NONCOGNATE NUCLEOTIDES BY DNA-POLYMERASE-ALPHA 1994
• 3'-AZIDO-3'-DEOXYTHYMIDINE POTENTLY INHIBITS PROTEIN GLYCOSYLATION - A NOVEL MECHANISM FOR AZT CYTOTOXICITY 1994
• Selective binding of Escherichia coli RNA polymerase to topoisomers of minicircles carrying the TAC16 and TAC17 promoters. 1994
• POSTTRANSCRIPTIONAL REGULATION OF RAT ALPHA-CARDIAC MYOSIN HEAVY-CHAIN GENE-EXPRESSION 1994
• HETEROLOGOUS EXPRESSION OF A CARDIOMYOPATHIC MYOSIN THAT IS DEFECTIVE IN ITS ACTIN INTERACTION 1994
• Differential effects of translational inhibition in cis and in trans on the decay of the unstable yeast MFA2 mRNA 1994
• ACTIVATING AND INHIBITORY HEPARIN SEQUENCES FOR FGF-2 (BASIC FGF) - DISTINCT REQUIREMENTS FOR FGF-1, FGF-2, AND FGF-4 1993
• HIV nucleocapsid protein. Expression in Escherichia coli, purification, and characterization. 1993
• Human immunodeficiency virus reverse transcriptase. Expression in Escherichia coli, purification, and characterization of a functionally and structurally asymmetric dimeric polymerase. 1993
• ACTIVATION OF THE PHOSPHOSIGNALING PROTEIN CHEY .1. ANALYSIS OF THE PHOSPHORYLATED CONFORMATION BY F-19 NMR AND PROTEIN ENGINEERING 1993
• ACTIVATION OF THE PHOSPHOSIGNALING PROTEIN CHEY .2. ANALYSIS OF ACTIVATED MUTANTS BY F-19 NMR AND PROTEIN ENGINEERING 1993
• RNA CATALYSIS BY A GROUP-I RIBOZYME - DEVELOPING A MODEL FOR TRANSITION-STATE STABILIZATION 1992
• Coordinated leading- and lagging-strand synthesis at the Escherichia coli DNA replication fork. IV. Reconstitution of an asymmetric, dimeric DNA polymerase III holoenzyme. 1992
• Coordinated leading- and lagging-strand synthesis at the Escherichia coli DNA replication fork. V. Primase action regulates the cycle of Okazaki fragment synthesis. 1992
• Fluorescence energy transfer between the primer and the beta subunit of the DNA polymerase III holoenzyme. 1992
• MECHANISM OF POLYETHYLENE-GLYCOL INTERACTION WITH THE MOLTEN GLOBULE FOLDING INTERMEDIATE OF BOVINE CARBONIC ANHYDRASE-B 1992
• DNA polymerase III holoenzyme. Components, structure, and mechanism of a true replicative complex. 1991
• Proofreading activity of DNA polymerase III responds like elongation activity to auxiliary subunits. 1991
• Escherichia coli DNA polymerase II is stimulated by DNA polymerase III holoenzyme auxiliary subunits. 1991
• THE ISOFORMS OF YEAST CYTOCHROME-C-OXIDASE SUBUNIT-V ALTER THE INVIVO KINETIC-PROPERTIES OF THE HOLOENZYME 1991
• Dissociation of the DNA polymerase III holoenzyme beta 2 subunits is accompanied by conformational change at distal cysteines 333. 1990
• EXPRESSION OF ACTIN IN ESCHERICHIA-COLI - AGGREGATION, SOLUBILIZATION, AND FUNCTIONAL-ANALYSIS 1990
• DNA PRIMASE - PROCESSIVITY AND THE PRIMASE TO POLYMERASE ALPHA-ACTIVITY SWITCH 1990
• MITOCHONDRIAL IMPORT OF CYTOCHROME-C OXIDASE SUBUNIT-VIIA IN SACCHAROMYCES-CEREVISIAE - IDENTIFICATION OF SEQUENCES REQUIRED FOR MITOCHONDRIAL LOCALIZATION INVIVO 1990
• ISOLATION OF A RECEPTOR FOR ACIDIC AND BASIC FIBROBLAST GROWTH-FACTOR FROM EMBRYONIC CHICK 1989
• ISOLATION AND CHARACTERIZATION OF A YEAST-STRAIN CARRYING A MUTATION IN THE MITOCHONDRIAL PROMOTER FOR COX2 1989
• Glutamate overcomes the salt inhibition of DNA polymerase III holoenzyme. 1989
• A ROLE FOR MEMBRANE-POTENTIAL IN THE BIOGENESIS OF CYTOCHROME-C OXIDASE SUBUNIT-II, A MITOCHONDRIAL GENE-PRODUCT 1989
• TRANSCRIPTION OF YEAST COX6, THE GENE FOR CYTOCHROME-C OXIDASE SUBUNIT-VI, IS DEPENDENT ON HEME AND ON THE HAP2 GENE 1989
• STRUCTURE OF A BACTERIAL SENSORY RECEPTOR - A SITE-DIRECTED SULFHYDRYL STUDY 1988
• THE ROLE OF THE TRP1 GENE IN YEAST TRYPTOPHAN BIOSYNTHESIS 1988
• Monoclonal antibodies specific for the tau subunit of the DNA polymerase III holoenzyme of Escherichia coli. Use to demonstrate that tau is the product of the dnaZX gene and that both it and gamma, the dnaZ gene product, are integral components of the same enzyme assembly. 1987
• CLONING AND CHARACTERIZATION OF THE SCALLOP ESSENTIAL AND REGULATORY MYOSIN LIGHT CHAIN CDNAS 1987
• Characterization of 2'(3')-trinitrophenyl-ATP as an inhibitor of ATP-dependent initiation complex formation between the DNA polymerase III holoenzyme and primed DNA. 1987
• Properties of initiation complexes formed between Escherichia coli DNA polymerase III holoenzyme and primed DNA in the absence of ATP. 1987
• DNA FUNCTIONAL-GROUPS REQUIRED FOR FORMATION OF OPEN COMPLEXES BETWEEN ESCHERICHIA-COLI RNA-POLYMERASE AND THE LAMBDA PR PROMOTER - IDENTIFICATION VIA BASE ANALOG SUBSTITUTIONS 1987
• CHARACTERIZATION OF COX9, THE NUCLEAR GENE ENCODING THE YEAST MITOCHONDRIAL PROTEIN CYTOCHROME-C-OXIDASE SUBUNIT VIIA - SUBUNIT VIIA LACKS A LEADER PEPTIDE AND IS AN ESSENTIAL COMPONENT OF THE HOLOENZYME 1986
• COX8, THE STRUCTURAL GENE FOR YEAST CYTOCHROME-C-OXIDASE SUBUNIT-VIII - DNA-SEQUENCE AND GENE DISRUPTION INDICATE THAT SUBUNIT-VIII IS REQUIRED FOR MAXIMAL LEVELS OF CELLULAR RESPIRATION AND IS DERIVED FROM A PRECURSOR WHICH IS EXTENDED AT BOTH ITS NH2 AND COOH TERMINI 1986
• Chemical characterization and purification of the beta subunit of the DNA polymerase III holoenzyme from an overproducing strain. 1986
• NUCLEAR FUNCTIONS REQUIRED FOR CYTOCHROME-C-OXIDASE BIOGENESIS IN SACCHAROMYCES-CEREVISIAE - CHARACTERIZATION OF MUTANTS IN 34 COMPLEMENTATION GROUPS 1986
• EFFECT OF REPLACING URIDINE-33 IN YEAST TRANSFER RNAPHE ON THE REACTION WITH RIBOSOMES 1986
• Effect of replacing uridine 33 in yeast tRNAPhe on the reaction with ribosomes. 1986
• THE NUCLEAR-CODED SUBUNITS OF YEAST CYTOCHROME-C-OXIDASE - THE AMINO-ACID-SEQUENCES OF SUBUNITS-VII AND SUBUNITS-VIIA, STRUCTURAL SIMILARITIES BETWEEN THE 3 SMALLEST POLYPEPTIDES OF THE HOLOENZYME, AND IMPLICATIONS FOR BIOGENESIS 1986
• The beta subunit of the Escherichia coli DNA polymerase III holoenzyme interacts functionally with the catalytic core in the absence of other subunits. 1986
• The minimal structure containing the band 3 anion transport site. A 35Cl NMR study. 1985
• BACTERIOPHAGE-T4 REGA PROTEIN - PURIFICATION OF A TRANSLATIONAL REPRESSOR 1985
• EVIDENCE THAT ANION TRANSPORT BY BAND-3 PROCEEDS VIA A PING-PONG MECHANISM INVOLVING A SINGLE TRANSPORT SITE - A CL-35 NMR-STUDY 1985
• THE KINETIC-EQUATION FOR THE CHLORIDE TRANSPORT CYCLE OF BAND-3 - A CL-35 AND CL-37 NMR-STUDY 1985
• THE MINIMAL STRUCTURE CONTAINING THE BAND-3 ANION TRANSPORT SITE - A CL-35 NMR-STUDY 1985
• Monoclonal antibodies specific for the alpha subunit of the Escherichia coli DNA polymerase III holoenzyme. 1984
• Adenosine 5'-O-(3-thiotriphosphate) can support the formation of an initiation complex between the DNA polymerase III holoenzyme and primed DNA. 1984
• Failure of translational repression in the phage f2 op3 mutant is not due to an altered coat protein-RNA interaction. 1984
• CHLORIDE BINDING TO THE ANION TRANSPORT BINDING-SITES OF BAND-3 - A CL-35 NMR-STUDY 1984
• DIRECT OBSERVATION OF THE TRANSMEMBRANE RECRUITMENT OF BAND-3 TRANSPORT SITES BY COMPETITIVE INHIBITORS - A CL-35 NMR-STUDY 1984
• HALIDE BINDING BY THE PURIFIED HALORHODOPSIN CHROMOPROTEIN .2. NEW CHLORIDE-BINDING SITES REVEALED BY CL-35 NMR 1984
• ISOLATION AND SEQUENCE OF THE STRUCTURAL GENE FOR CYTOCHROME-C OXIDASE SUBUNIT-VI FROM SACCHAROMYCES-CEREVISIAE 1984
• MITOCHONDRIAL GENE-EXPRESSION IN SACCHAROMYCES CEREVISIAE .1. OPTIMAL CONDITIONS FOR PROTEIN-SYNTHESIS IN ISOLATED-MITOCHONDRIA 1984
• MITOCHONDRIAL GENE-EXPRESSION IN SACCHAROMYCES-CEREVISIAE .2. FIDELITY OF TRANSLATION IN ISOLATED-MITOCHONDRIA FROM WILD-TYPE AND RESPIRATORY-DEFICIENT MUTANT-CELLS 1984
• QUANTITATION OF ENERGY COUPLING BETWEEN CA-2+, CALMODULIN, SKELETAL-MUSCLE MYOSIN LIGHT CHAIN KINASE, AND KINASE SUBSTRATES 1984
• THE NUCLEAR-CODED SUBUNITS OF YEAST CYTOCHROME-C OXIDASE .1. FRACTIONATION OF THE HOLOENZYME INTO CHEMICALLY PURE POLYPEPTIDES AND THE IDENTIFICATION OF 2 NEW SUBUNITS USING SOLVENT-EXTRACTION AND REVERSED PHASE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY 1984
• THE NUCLEAR-CODED SUBUNITS OF YEAST CYTOCHROME-C OXIDASE .2. THE AMINO-ACID-SEQUENCE OF SUBUNIT-VIII AND A MODEL FOR ITS DISPOSITION IN THE INNER MITOCHONDRIAL-MEMBRANE 1984
• THE NUCLEAR-CODED SUBUNITS OF YEAST CYTOCHROME-C OXIDASE .3. IDENTIFICATION OF HOMOLOGOUS SUBUNITS IN YEAST, BOVINE HEART, AND NEUROSPORA-CRASSA CYTOCHROME-C OXIDASES 1984
• Excess beta subunit can bypass the ATP requirement for highly processive synthesis by the Escherichia coli DNA polymerase III holoenzyme. 1983
• NUCLEAR GENES FOR MITOCHONDRIAL PROTEINS - IDENTIFICATION AND ISOLATION OF A STRUCTURAL GENE FOR SUBUNIT-V OF YEAST CYTOCHROME-C OXIDASE 1983
• POINT MUTATIONS OF THE ADENOVIRUS MAJOR LATE PROMOTER WITH DIFFERENT TRANSCRIPTIONAL EFFICIENCIES INVITRO 1983
• RECOGNITION, ISOLATION, AND CHARACTERIZATION OF RAT-LIVER D-METHYLMALONYL COENZYME-A HYDROLASE 1983
• The beta subunit of the DNA polymerase III holoenzyme becomes inaccessible to antibody after formation of an initiation complex with primed DNA. 1982
• Independent locations of kinase and 3'-phosphatase activities on T4 polynucleotide kinase. 1982
• Isolation and characterization of two mutant forms of T4 polynucleotide kinase. 1982
• Size classes of products synthesized processively by two subassemblies of Escherichia coli DNA polymerase III holoenzyme. 1982
• Purification and characterization of DNA polymerase III'. Identification of tau as a subunit of the DNA polymerase III holoenzyme. 1982
• A CALORIMETRIC INVESTIGATION OF THE INTERACTION OF THE LAC REPRESSOR WITH INDUCER 1982
• Size classes of products synthesized processively by DNA polymerase III and DNA polymerase III holoenzyme of Escherichia coli. 1981
• Purification and characterization of the beta subunit of the DNA polymerase III holoenzyme of Escherichia coli. 1980
• INHIBITION OF ADENYLATE-CYCLASE BY THE 2',3'-DIALDEHYDE OF ADENOSINE-TRIPHOSPHATE 1980
• DNA polymerase III of Escherichia coli. Purification and identification of subunits. 1979
• REGULATION OF GENE-32 EXPRESSION DURING BACTERIOPHAGE-T4 INFECTION OF ESCHERICHIA-COLI 1976
• TRANSLATIONAL, AUTOGENOUS REGULATION OF GENE-32 EXPRESSION DURING BACTERIOPHAGE-T4 INFECTION 1976
• Total Synthesis of the Structural Gene for the Precursor of a Tyrosine Suppressor Transfer RNA from Escherichia coli 1. General Introduction 1976
• Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 10. Enzymatic joining of chemically synthesized segments to form the DNA duplex corresponding to the nucleotide sequence 86-126 1976
• Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 11. Enzymatic joining to form the total DNA duplex 1976
• Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 3. Synthesis of deoxyribopolynucleotide segments corresponding to the nucleotide sequence 27-51 1976
• Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 4. Synthesis of deoxyribopolynucleotide segments corresponding to the nucleotide sequence 47-78 1976
• Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 5. Synthesis of the deoxyribopolynucleotide segments representing the nucleotide sequence 71-103 1976
• Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 6. Synthesis of the deoxyribopolynucleotide segments corresponding to the nucleotide sequence 100-126 1976
• CALCULATED EQUILIBRIA OF PHOSPHOCREATINE AND ADENOSINE PHOSPHATES DURING UTILIZATION OF HIGH-ENERGY PHOSPHATE BY MUSCLE 1974
• Assembly Checkpoint of the Proteasome is Mediated by Coordinated Actions of Proteasomal ATPase Chaperones 2023
• Mediator kinase inhibition suppresses chronic inflammation in Down syndrome 2023
• Septin filaments interact with AP-3 and are required for trafficking via the AP-3 pathway in budding yeast 2023