Journal of Biological Chemistry

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Analysis of Poly(ethylene terephthalate) degradation kinetics of evolved IsPETase variants using a surface crowding model. 2024
The PARN, TOE1, and USB1 RNA deadenylases and their roles in RNA 2023
Distinct effects of two hearing loss-associated mutations in the sarcomeric myosin MYH7b 2023
The penultimate step of proteasomal ATPase assembly is mediated by a switch dependent on the chaperone Nas2 2023
Functional divergence of the sarcomeric myosin, MYH7b, supports species-specific biological roles 2023
Intrinsically disordered regions that drive phase separation form a robustly distinct protein class 2023
Systematic mutagenesis of TFIIH subunit p52/Tfb2 identifies residues required for XPB/Ssl2 subunit function and genetic interactions with TFB6 2022
Manganese promotes α-synuclein amyloid aggregation through the induction of protein phase transition 2022
Beta turn propensity and a model polymer scaling exponent identify intrinsically disordered phase-separating proteins 2021
Deconvolution of multiplexed transcriptional responses to wood smoke particles defines rapid aryl hydrocarbon receptor signaling dynamics 2021
Calcium-dependent and -independent lipid transfer mediated by tricalbins in yeast 2021
Defective insulin receptor signaling in hPSCs skews pluripotency and negatively perturbs neural differentiation 2021
Global proteomics of Ubqln2-based murine models of ALS 2021
Myosin 7b is a regulatory long noncoding RNA (lncMYH7b) in the human heart 2021
Structure and kinetics of indole-3-glycerol phosphate synthase from Pseudomonas aeruginosa: Decarboxylation is not essential for indole formation 2020
RNase L promotes the formation of unique ribonucleoprotein granules distinct from stress granules 2020
Inducible Exoc7/Exo70 knockout reveals a critical role of the exocyst in insulin-regulated GLUT4 exocytosis 2019
Myosin motor domains carrying mutations implicated in early or late onset hypertrophic cardiomyopathy have similar properties 2019
The ATPase cycle of human muscle myosin II isoforms: Adaptation of a single mechanochemical cycle for different physiological roles 2019
The plant triterpenoid celastrol blocks PINK1-dependent mitophagy by disrupting PINK1's association with the mitochondrial protein TOM20 2019
15-Deoxy-^12,14-prostaglandin J2 promotes phosphorylation of eukaryotic initiation factor 2 and activates the integrated stress response 2019
Two alternative mechanisms regulate the onset of chaperone-mediated assembly of the proteasomal ATPases 2019
The N-peptide-binding mode is critical to Munc18-1 function in synaptic exocytosis 2018
Interleukin-37 treatment of mice with metabolic syndrome improves insulin sensitivity and reduces pro-inflammatory cytokine production in adipose tissue 2018
The complex structure and function of Mediator 2018
Dilated cardiomyopathy myosin mutants have reduced force-generating capacity 2018
Sorafenib targets the mitochondrial electron transport chain complexes and ATP synthase to activate the PINK1-Parkin pathway and modulate cellular drug response 2017
Cobalamin riboswitches exhibit a broad range of ability to discriminate between methylcobalamin and adenosylcobalamin 2017
The Pseudouridine Synthase RPUSD4 Is an Essential Component of Mitochondrial RNA Granules 2017
Developmental Defects of Caenorhabditis elegans Lacking Branched-chain α-Ketoacid Dehydrogenase Are Mainly Caused by Monomethyl Branched-chain Fatty Acid Deficiency 2016
Rapid Fine Conformational Epitope Mapping Using Comprehensive Mutagenesis and Deep Sequencing 2015
Two-step Ligand Binding in a (βα)₈ Barrel Enzyme SUBSTRATE-BOUND STRUCTURES SHED NEW LIGHT ON THE CATALYTIC CYCLE OF HisA 2015
Producing Glucose 6-Phosphate from Cellulosic Biomass 2015
Histone Core Phosphorylation Regulates DNA Accessibility 2015
DNA Polymerase alpha Subunit Residues and Interactions Required for Efficient Initiation Complex Formation Identified by a Genetic Selection 2015
Identification of Subunit Binding Positions on a Model Fork and Displacements That Occur during Sequential Assembly of the Escherichia coli Primosome 2015
Structure-guided Mutational Analysis of Gene Regulation by the Bacillus subtilis pbuE Adenine-responsive Riboswitch in a Cellular Context 2015
Crystal Structure of BamB Bound to a Periplasmic Domain Fragment of BamA, the Central Component of the β-Barrel Assembly Machine 2015
Role of Glucose Metabolism and ATP in Maintaining PINK1 Levels during Parkin-mediated Mitochondrial Damage Responses 2015
The N- and C-terminal Domains of Tomosyn Play Distinct Roles in Soluble N-Ethylmaleimide-sensitive Factor Attachment Protein Receptor Binding and Fusion Regulation 2014
The p38β Mitogen-activated Protein Kinase Possesses an Intrinsic Autophosphorylation Activity, Generated by a Short Region Composed of the α-G Helix and MAPK Insert 2014
The Hypertrophic Cardiomyopathy Myosin Mutation R453C Alters ATP Binding and Hydrolysis of Human Cardiac β- Myosin* 2014
Programmed Cell Death Protein 5 Interacts with the Cytosolic Chaperonin Containing Tailless Complex Polypeptide 1 (CCT) to Regulate beta-Tubulin Folding 2014
Identification of Global Ferredoxin Interaction Networks in Chlamydomonas reinhardtii 2013
Inhibition of Telomerase Recruitment and Cancer Cell Death 2013
The Superfast Human Extraocular Myosin Is Kinetically Distinct from the Fast Skeletal IIa, IIb, and IId Isoforms 2013
Synip Arrests Soluble N-Ethylmaleimide-sensitive Factor Attachment Protein Receptor (SNARE)-dependent Membrane Fusion as a Selective Target Membrane SNARE-binding Inhibitor 2013
The PriA Replication Restart Protein Blocks Replicase Access Prior to Helicase Assembly and Directs Template Specificity through Its ATPase Activity 2013
The Chemical Synthesis of DNA/RNA: Our Gift to Science 2013
Genetic Analysis of the Hox Hydrogenase in the Cyanobacterium Synechocystis sp PCC 6803 Reveals Subunit Roles in Association, Assembly, Maturation, and Function 2012
Human Pumilio Proteins Recruit Multiple Deadenylases to Efficiently Repress Messenger RNAs 2012
Alternative Modes of Binding of Poly(ADP-ribose) Polymerase 1 to Free DNA and Nucleosomes 2012
Product Binding Varies Dramatically between Processive and Nonprocessive Cellulase Enzymes 2012
Structural Insights into Apoptotic DNA Degradation by CED-3 Protease Suppressor-6 (CPS-6) from Caenorhabditis elegans 2012
Histidine 66 in Escherichia coli elongation factor tu selectively stabilizes aminoacyl-tRNAs. 2012
Toward a Systems Biology Perspective on Enzyme Evolution 2012
Endosomal Na+ (K+)/H+ Exchanger Nhx1/Vps44 Functions Independently and Downstream of Multivesicular Body Formation 2011
Histone Chaperone FACT Coordinates Nucleosome Interaction through Multiple Synergistic Binding Events 2011
Structural Defects in the Regulatory Particle-Core Particle Interface of the Proteasome Induce a Novel Proteasome Stress Response 2011
The Linker Region of MacroH2A Promotes Self-association of Nucleosomal Arrays 2011
MicroRNA-378 Targets the Myogenic Repressor MyoR during Myoblast Differentiation 2011
The Histone Chaperone FACT: Structural Insights and Mechanisms for Nucleosome Reorganization 2011
Probing Carbohydrate Product Expulsion from a Processive Cellulase with Multiple Absolute Binding Free Energy Methods 2011
Cellular Abundance of Mps1 and the Role of Its Carboxyl Terminal Tail in Substrate Recruitment 2010
Only One ATP-binding DnaX Subunit Is Required for Initiation Complex Formation by the Escherichia coli DNA Polymerase III Holoenzyme 2010
Disruption of Lysosome Function Promotes Tumor Growth and Metastasis in Drosophila 2010
Strand Displacement by DNA Polymerase III Occurs through a τ-ψ-χ Link to Single-stranded DNA-binding Protein Coating the Lagging Strand Template 2009
Two Pathways for Cyclooxygenase-2 Protein Degradation in Vivo 2009
Genetically Encoded Sensors to Elucidate Spatial Distribution of Cellular Zinc 2009
Analysis of a Critical Interaction within the Archaeal Box C/D Small Ribonucleoprotein Complex 2009
Budding Yeast Centrosome Duplication Requires Stabilization of Spc29 via Mps1-mediated Phosphorylation 2009
TATA-binding Protein and Transcription Factor IIB Induce Transcript Slipping during Early Transcription by RNA Polymerase II 2009
Initiation of New DNA Strands by the Herpes Simplex Virus-1 Primase-Helicase Complex and Either Herpes DNA Polymerase or Human DNA Polymerase α 2009
Isolation of Intrinsically Active (MEK-independent) Variants of the ERK Family of Mitogen-activated Protein (MAP) Kinases 2008
A Thermodynamic Model for Nap1-Histone Interactions 2008
The Cth2 ARE-binding Protein Recruits the Dhh1 Helicase to Promote the Decay of Succinate Dehydrogenase SDH4 mRNA in Response to Iron Deficiency 2008
Crystal structure of the lysine riboswitch regulatory mRNA element 2008
The reticulon and DP1/Yop1p proteins form immobile oligomers in the tubular endoplasmic reticulum 2008
BI-1 Regulates Endoplasmic Reticulum Ca2+ Homeostasis Downstream of Bcl-2 Family Proteins 2008
Suppression of in vivo β-amyloid peptide toxicity by overexpression of the HSP-16.2 small chaperone protein 2008
Mps1 activation loop autophosphorylation enhances kinase activity 2007
Activation of Mps1 promotes transforming growth factor-β-independent Smad signaling 2007
alpha-7 Nicotinic receptor gene promoter polymorphisms in inbred mice affect expression in a cell type-specific fashion 2007
The histone variant macro-H2A preferentially forms "hybrid nucleosomes" 2006
Global gene expression analysis of ERK5 and ERK1/2 signaling reveals a role for HIF-1 in ERK5-mediated responses 2006
Sodium butyrate ameliorates histone hypoacetylation and neurodegenerative phenotypes in a mouse model for DRPLA 2006
The NH2-terminal php domain of the alpha subunit of the Escherichia coli replicase binds the epsilon proofreading subunit. 2006
RNA aptamers targeting the cell death inhibitor CED-9 induce cell killing in Caenorhabditis elegans 2006
Conversion of green fluorescent protein into a toxic, aggregation-prone protein by C-terminal addition of a short peptide 2006
Discovery and characterization of the cryptic psi subunit of the pseudomonad DNA replicase. 2005
The sequence at specific positions in the early transcribed region sets the rate of transcript synthesis by RNA polymerase II in vitro 2005
YxiN is a modular protein combining a DEx(D/H) core and a specific RNA-binding domain. 2005
The core histone n-terminal tail domains function independently and additively during salt-dependent oligomerization of nucleosomal arrays 2005
POT1 stimulates RecQ helicases WRN and BLM to unwind telomeric DNA substrates 2005
Ubiquitination of p27(Kip1) requires physical interaction with cyclin E and probable phosphate recognition by SKP2 2005
Switching human telomerase on and off with hPOT1 protein in vitro 2005
Myocyte enhancer factor-2 and serum response factor binding elements regulate fast myosin heavy chain transcription in vivo 2005
Reconstitution of a minimal DNA replicase from Pseudomonas aeruginosa and stimulation by non-cognate auxiliary factors. 2005
Yeast flavohemoglobin, a nitric oxide oxidoreductase, is located in both the cytosol and the mitochondrial matrix 2005
Expression of a RecQ helicase homolog affects progression through crisis in fission yeast lacking telomerase 2005
A role for Pet100p in the assembly of yeast cytochrome c oxidase -: Interaction with a subassembly that accumulates in a pet100 mutant 2005
Nucleosome assembly protein 1 exchanges histone H2A-H2B dimers and assists nucleosome sliding 2005
alpha-conotoxin BuIA, a novel peptide from Conus bullatus, distinguishes among neuronal nicotinic acetylcholine receptors 2005
Mitochondrial protein oxidation in yeast mutants lacking manganese- (MnSOD) or copper- and zinc-containing superoxide dismutase (CuZnSOD) - Evidence that MnSOD and CuZnSOD have both unique and overlapping functions in protecting mitochondrial proteins from oxidative damage 2004
Molecular and biochemical characterization of the Skp2-Cks1 binding interface 2004
Dependence of site-2 protease cleavage of ATF6 on prior site-1 protease digestion is determined by the size of the luminal domain of ATF6 2004
Wnt10b inhibits development of white and brown adipose tissues 2004
The basic leucine zipper domain of c-Jun functions in transcriptional activation through interaction with the N terminus of human TATA-binding protein-associated factor-1 (human TAF_II250) 2004
A new fluorescence resonance energy transfer approach demonstrates that the histone variant H2AZ stabilizes the histone octamer within the nucleosome 2004
A mechanism of oxygen sensing in yeast - Multiple oxygen-responsive steps in the heme biosynthetic pathway affect Hap1 activity 2003
Preferential binding of the histone (H3-H4)₂ tetramer by NAP1 is mediated by the amino-terminal histone tails 2003
A negatively charged amino acid in Skp2 is required for Skp2-Cks1 interaction and ubiquitination of p27(Kip1) 2003
Yin Yang 1 is increased in human heart failure and represses the activity of the human α-myosin heavy chain promoter 2003
Purification and mass spectrometric identification of GA-binding protein (GABP) as the functional pituitary Ets factor binding to the basal transcription element of the prolactin promoter 2003
Congo red populates partially unfolded states of an amyloidogenic protein to enhance aggregation and amyloid fibril formation 2003
Intracellular calcium and myosin isoform transitions - Calcineurin and calcium-calmodulin kinase pathways regulate preferential activation of the iia myosin heavy chain promoter 2002
Exposure of yeast cells to anoxia induces transient oxidative stress - Implications for the induction of hypoxic genes 2002
Kinetics and energetics of assembly, nucleation, and growth of aggregates and fibrils for an amyloidogenic protein - Insights into transition states from pressure, temperature, and co-solute studies 2002
Phosphatase inhibition leads to histone deacetylases 1 and 2 phosphorylation and disruption of corepressor interactions 2002
DNA polymerase III holoenzyme from Thermus thermophilus identification, expression, purification of components, and use to reconstitute a processive replicase. 2002
A three-domain structure for the delta subunit of the DNA polymerase III holoenzyme delta domain III binds delta' and assembles into the DnaX complex. 2002
The luminal domain of ATF6 senses endoplasmic reticulum (ER) stress and causes translocation of ATF6 from the ER to the Golgi 2002
Global regulation of post-translational modifications on core histones 2002
Phosphorylation of MEK1 by cdk5/p35 down-regulates the mitogen-activated protein kinase pathway 2002
Carboxyl-terminal domain III of the delta' subunit of DNA polymerase III holoenzyme binds DnaX and supports cooperative DnaX complex assembly. 2001
High pressure refolding of recombinant human growth hormone from insoluble aggregates - Structural transformations, kinetic barriers, and energetics 2001
Constitutive activation of extracellular signal-regulated kinase 2 by synergistic point mutations 2001
Peroxisome proliferator-activated receptor γ inhibits transforming growth factor β-induced connective tissue growth factor expression in human aortic smooth muscle cells by interfering with Smad3 2001
Different pathways regulate expression of the skeletal myosin heavy chain genes 2001
Carboxyl-terminal domain III of the delta' subunit of the DNA polymerase III holoenzyme binds delta. 2001
A novel mechanism for regulating transforming growth factor β (TGF-β) signaling -: Functional modulation of type III TGF-β receptor expression through interaction with the PDZ domain protein, GIPC 2001
tau binds and organizes Escherichia coli replication proteins through distinct domains: domain III, shared by gamma and tau, oligomerizes DnaX. 2001
Assembly of DNA polymerase III holoenzyme: co-assembly of gamma and tau is inhibited by DnaX complex accessory proteins but stimulated by DNA polymerase III core. 2001
The delta and delta ' subunits of the DNA polymerase III holoenzyme are essential for initiation complex formation and processive elongation. 2001
c-Jun binds the N terminus of human TAF(II)250 to derepress RNA polymerase II transcription in vitro 2001
Modulation of the G protein regulator phosducin by Ca²⁺/calmodulin-dependent protein kinase II phosphorylation and 14-3-3 protein binding 2001
Yeast Mps1p phosphorylates the spindle pole component Spc110p in the N-terminal domain 2001
Effects of anoxia and the mitochondrion on expression of aerobic nuclear COX genes in yeast - Evidence for a signaling pathway from the mitochondrial genome to the nucleus 2001
Tau binds and organizes Escherichia coli replication proteins through distinct domains. Domain III, shared by gamma and tau, binds delta delta ' and chi psi. 2001
tau binds and organizes Escherichia coli replication proteins through distinct domains. Domain IV, located within the unique C terminus of tau, binds the replication fork, helicase, DnaB. 2001
tau binds and organizes Escherichia coli replication through distinct domains. Partial proteolysis of terminally tagged tau to determine candidate domains and to assign domain V as the alpha binding domain. 2001
Counteracting effects of renal solutes on amyloid fibril formation by immunoglobulin light chains 2001
A kinetic model for the early steps of RNA synthesis by human RNA polymerase II 2000
The hexameric eukaryotic MCM helicase: Building symmetry from nonidentical parts 2000
Entrapping intermediates of thermal aggregation in α-helical proteins with low concentration of guanidine hydrochloride 2000
3 '-azidothymidine potently inhibits the biosynthesis of highly branched N-linked oligosaccharides and poly-N-acetyllactosamine chains in cells 2000
Activation of ATF6 and an ATF6 DNA binding site by the endoplasmic reticulum stress response 2000
A mutant of Tetrahymena telomerase reverse transcriptase with increased processivity 2000
Importin β mediates nuclear translocation of Smad 3 2000
Cysteine-rich fibroblast growth factor receptor alters secretion and intracellular routing of fibroblast growth factor 3 2000
Characterization of the unique C terminus of the Escherichia coli tau DnaX protein. Monomeric C-tau binds alpha AND DnaB and can partially replace tau in reconstituted replication forks. 2000
The DnaX-binding subunits delta' and psi are bound to gamma and not tau in the DNA polymerase III holoenzyme. 2000
Thermodynamic modulation of light chain amyloid fibril formation 2000
Chaperone activity of a chimeric GroEL protein that can exist in a single or double ring form 1999
Targeted Mutations in a Trametes villosa Laccase 1999
Nuclear localization of mitogen-activated protein kinase kinase 1 (MKK1) is promoted by serum stimulation and G2-M progression - Requirement for phosphorylation at the activation lip and signaling downstream of MKK 1999
Transforming growth factor-β induces formation of a dithiothreitol-resistant type I type II receptor complex in live cells 1999
Mismatch extension by Escherichia coli DNA polymerase III holoenzyme. 1999
Quantitative assessment of EF-1α•GTP binding to aminoacyl-tRNAs, aminoacyl-viral RNA, and tRNA shows close correspondence to the RNA binding properties of EF-Tu 1999
Detection of a conserved alpha-helix in the kinase-docking region of the aspartate receptor by cysteine and disulfide scanning 1998
The base substitution and frameshift fidelity of Escherichia coli DNA polymerase III holoenzyme in vitro. 1998
The chi psi subunits of DNA polymerase III holoenzyme bind to single-stranded DNA-binding protein (SSB) and facilitate replication of an SSB-coated template. 1998
Role of the core DNA polymerase III subunits at the replication fork. Alpha is the only subunit required for processive replication. 1998
Feedback regulation of Raf-1 and mitogen-activated protein kinase (MAP) kinase kinases 1 and 2 by MAP kinase phosphatase-1 (MKP-1) 1998
Independent folding and ligand specificity of the C2 calcium-dependent lipid binding domain of cytosolic phospholipase A₂ 1998
Cysteine and disulfide scanning reveals a regulatory alpha-helix in the cytoplasmic domain of the aspartate receptor 1997
Phosphorylation of I kappa B-alpha inhibits its cleavage by caspase CPP32 in vitro 1997
Destabilization of peptide binding and interdomain communication by an E543K mutation in the bovine 70-kDa heat shock cognate protein, a molecular chaperone. 1997
Involvement of a specific metal ion in the transition of the hammerhead ribozyme to its catalytic conformation 1997
Electron paramagnetic resonance studies of succinate:ubiquinone oxidoreductase from Paracoccus denitrificans - Evidence for a magnetic interaction between the 3Fe-4S cluster and cytochrome b 1997
Effects of oxygen concentration on the expression of cytochrome c and cytochrome c oxidase genes in yeast 1997
Single-stranded RNA recognition by the bacteriophage T4 translational repressor, RegA 1997
Structural requirements for major histocompatibility complex class II invariant chain trafficking in polarized Madin-Darby canine kidney cells 1997
Identification and characterization of a fibroblast growth factor (FGF) binding domain in the cysteine-rich FGF receptor 1997
Mass spectrometric analysis of 40 S ribosomal proteins from rat-1 fibroblasts 1996
Contributions of the Mitogen-activated Protein (MAP) Kinase Backbone and Phosphorylation Loop to MEK Specificity 1996
Function and expression of flavohemoglobin in Saccharomyces cerevisiae - Evidence for a role in the oxidative stress response 1996
G alpha 12 and G alpha 13 regulate extracellular signal-regulated kinase and c-Jun kinase pathways by different mechanisms in COS-7 cells 1996
tau couples the leading- and lagging-strand polymerases at the Escherichia coli DNA replication fork. 1996
Biotin tagging deletion analysis of domain limits involved in protein-macromolecular interactions. Mapping the tau binding domain of the DNA polymerase III alpha subunit. 1996
Identification of the beta-binding domain of the alpha subunit of Escherichia coli polymerase III holoenzyme. 1996
In vivo assembly of overproduced DNA polymerase III. Overproduction, purification, and characterization of the alpha, alpha-epsilon, and alpha-epsilon-theta subunits. 1996
Cloning and characterization of PET100, a gene required for the assembly of yeast cytochrome c oxidase 1996
In vivo assembly of the tau-complex of the DNA polymerase III holoenzyme expressed from a five-gene artificial operon. Cleavage of the tau-complex to form a mixed gamma-tau-complex by the OmpT protease. 1996
Tau protects beta in the leading-strand polymerase complex at the replication fork. 1996
Induction of mitogen-activated protein kinase phosphatase 1 by the stress-activated protein kinase signaling pathway but not by extracellular signal-regulated kinase in fibroblasts 1996
DnaX complex of Escherichia coli DNA polymerase III holoenzyme. Central role of tau in initiation complex assembly and in determining the functional asymmetry of holoenzyme. 1995
DnaX complex of Escherichia coli DNA polymerase III holoenzyme. Physical characterization of the DnaX subunits and complexes. 1995
DnaX complex of Escherichia coli DNA polymerase III holoenzyme. The chi psi complex functions by increasing the affinity of tau and gamma for delta.delta' to a physiologically relevant range. 1995
CONSERVATION OF LIGAND SPECIFICITY BETWEEN THE MAMMALIAN AND AMPHIBIAN FIBROBLAST GROWTH-FACTOR RECEPTORS 1995
LOCK ON OFF DISULFIDES IDENTIFY THE TRANSMEMBRANE SIGNALING HELIX OF THE ASPARTATE RECEPTOR 1995
3'-AZIDOTHYMIDINE (ZIDOVUDINE) INHIBITS GLYCOSYLATION AND DRAMATICALLY ALTERS GLYCOSPHINGOLIPID SYNTHESIS IN WHOLE CELLS AT CLINICALLY RELEVANT CONCENTRATIONS 1995
OLIGONUCLEOTIDES AS RESEARCH, DIAGNOSTIC, AND THERAPEUTIC AGENTS 1995
Escherichia coli DNA polymerase III holoenzyme subunits alpha, beta, and gamma directly contact the primer-template. 1995
ISOFORMS OF YEAST CYTOCHROME-C-OXIDASE SUBUNIT-V AFFECT THE BINUCLEAR REACTION-CENTER AND AFTER THE KINETICS OF INTERACTION WITH THE ISOFORMS OF YEAST CYTOCHROME-C 1995
Escherichia coli DNA polymerase III holoenzyme footprints three helical turns of its primer. 1994
Human immunodeficiency virus nucleocapsid protein accelerates strand transfer of the terminally redundant sequences involved in reverse transcription. 1994
THE BACTERIOPHAGE-T4 REGB RIBONUCLEASE - STIMULATION OF THE PURIFIED ENZYME BY RIBOSOMAL-PROTEIN-S1 1994
MISINCORPORATION OF NUCLEOTIDES BY CALF THYMUS DNA PRIMASE AND ELONGATION OF PRIMERS CONTAINING MULTIPLE NONCOGNATE NUCLEOTIDES BY DNA-POLYMERASE-ALPHA 1994
3'-AZIDO-3'-DEOXYTHYMIDINE POTENTLY INHIBITS PROTEIN GLYCOSYLATION - A NOVEL MECHANISM FOR AZT CYTOTOXICITY 1994
Selective binding of Escherichia coli RNA polymerase to topoisomers of minicircles carrying the TAC16 and TAC17 promoters. 1994
POSTTRANSCRIPTIONAL REGULATION OF RAT ALPHA-CARDIAC MYOSIN HEAVY-CHAIN GENE-EXPRESSION 1994
HETEROLOGOUS EXPRESSION OF A CARDIOMYOPATHIC MYOSIN THAT IS DEFECTIVE IN ITS ACTIN INTERACTION 1994
Differential effects of translational inhibition in cis and in trans on the decay of the unstable yeast MFA2 mRNA 1994
ACTIVATING AND INHIBITORY HEPARIN SEQUENCES FOR FGF-2 (BASIC FGF) - DISTINCT REQUIREMENTS FOR FGF-1, FGF-2, AND FGF-4 1993
HIV nucleocapsid protein. Expression in Escherichia coli, purification, and characterization. 1993
Human immunodeficiency virus reverse transcriptase. Expression in Escherichia coli, purification, and characterization of a functionally and structurally asymmetric dimeric polymerase. 1993
ACTIVATION OF THE PHOSPHOSIGNALING PROTEIN CHEY .1. ANALYSIS OF THE PHOSPHORYLATED CONFORMATION BY F-19 NMR AND PROTEIN ENGINEERING 1993
ACTIVATION OF THE PHOSPHOSIGNALING PROTEIN CHEY .2. ANALYSIS OF ACTIVATED MUTANTS BY F-19 NMR AND PROTEIN ENGINEERING 1993
RNA CATALYSIS BY A GROUP-I RIBOZYME - DEVELOPING A MODEL FOR TRANSITION-STATE STABILIZATION 1992
Coordinated leading- and lagging-strand synthesis at the Escherichia coli DNA replication fork. IV. Reconstitution of an asymmetric, dimeric DNA polymerase III holoenzyme. 1992
Coordinated leading- and lagging-strand synthesis at the Escherichia coli DNA replication fork. V. Primase action regulates the cycle of Okazaki fragment synthesis. 1992
Fluorescence energy transfer between the primer and the beta subunit of the DNA polymerase III holoenzyme. 1992
MECHANISM OF POLYETHYLENE-GLYCOL INTERACTION WITH THE MOLTEN GLOBULE FOLDING INTERMEDIATE OF BOVINE CARBONIC ANHYDRASE-B 1992
DNA polymerase III holoenzyme. Components, structure, and mechanism of a true replicative complex. 1991
Proofreading activity of DNA polymerase III responds like elongation activity to auxiliary subunits. 1991
Escherichia coli DNA polymerase II is stimulated by DNA polymerase III holoenzyme auxiliary subunits. 1991
THE ISOFORMS OF YEAST CYTOCHROME-C-OXIDASE SUBUNIT-V ALTER THE INVIVO KINETIC-PROPERTIES OF THE HOLOENZYME 1991
Dissociation of the DNA polymerase III holoenzyme beta 2 subunits is accompanied by conformational change at distal cysteines 333. 1990
EXPRESSION OF ACTIN IN ESCHERICHIA-COLI - AGGREGATION, SOLUBILIZATION, AND FUNCTIONAL-ANALYSIS 1990
DNA PRIMASE - PROCESSIVITY AND THE PRIMASE TO POLYMERASE ALPHA-ACTIVITY SWITCH 1990
MITOCHONDRIAL IMPORT OF CYTOCHROME-C OXIDASE SUBUNIT-VIIA IN SACCHAROMYCES-CEREVISIAE - IDENTIFICATION OF SEQUENCES REQUIRED FOR MITOCHONDRIAL LOCALIZATION INVIVO 1990
ISOLATION OF A RECEPTOR FOR ACIDIC AND BASIC FIBROBLAST GROWTH-FACTOR FROM EMBRYONIC CHICK 1989
ISOLATION AND CHARACTERIZATION OF A YEAST-STRAIN CARRYING A MUTATION IN THE MITOCHONDRIAL PROMOTER FOR COX2 1989
Glutamate overcomes the salt inhibition of DNA polymerase III holoenzyme. 1989
A ROLE FOR MEMBRANE-POTENTIAL IN THE BIOGENESIS OF CYTOCHROME-C OXIDASE SUBUNIT-II, A MITOCHONDRIAL GENE-PRODUCT 1989
TRANSCRIPTION OF YEAST COX6, THE GENE FOR CYTOCHROME-C OXIDASE SUBUNIT-VI, IS DEPENDENT ON HEME AND ON THE HAP2 GENE 1989
THE ROLE OF THE TRP1 GENE IN YEAST TRYPTOPHAN BIOSYNTHESIS 1988
Monoclonal antibodies specific for the tau subunit of the DNA polymerase III holoenzyme of Escherichia coli. Use to demonstrate that tau is the product of the dnaZX gene and that both it and gamma, the dnaZ gene product, are integral components of the same enzyme assembly. 1987
CLONING AND CHARACTERIZATION OF THE SCALLOP ESSENTIAL AND REGULATORY MYOSIN LIGHT CHAIN CDNAS 1987
Characterization of 2'(3')-trinitrophenyl-ATP as an inhibitor of ATP-dependent initiation complex formation between the DNA polymerase III holoenzyme and primed DNA. 1987
Properties of initiation complexes formed between Escherichia coli DNA polymerase III holoenzyme and primed DNA in the absence of ATP. 1987
DNA FUNCTIONAL-GROUPS REQUIRED FOR FORMATION OF OPEN COMPLEXES BETWEEN ESCHERICHIA-COLI RNA-POLYMERASE AND THE LAMBDA PR PROMOTER - IDENTIFICATION VIA BASE ANALOG SUBSTITUTIONS 1987
CHARACTERIZATION OF COX9, THE NUCLEAR GENE ENCODING THE YEAST MITOCHONDRIAL PROTEIN CYTOCHROME-C-OXIDASE SUBUNIT VIIA - SUBUNIT VIIA LACKS A LEADER PEPTIDE AND IS AN ESSENTIAL COMPONENT OF THE HOLOENZYME 1986
COX8, THE STRUCTURAL GENE FOR YEAST CYTOCHROME-C-OXIDASE SUBUNIT-VIII - DNA-SEQUENCE AND GENE DISRUPTION INDICATE THAT SUBUNIT-VIII IS REQUIRED FOR MAXIMAL LEVELS OF CELLULAR RESPIRATION AND IS DERIVED FROM A PRECURSOR WHICH IS EXTENDED AT BOTH ITS NH2 AND COOH TERMINI 1986
Chemical characterization and purification of the beta subunit of the DNA polymerase III holoenzyme from an overproducing strain. 1986
NUCLEAR FUNCTIONS REQUIRED FOR CYTOCHROME-C-OXIDASE BIOGENESIS IN SACCHAROMYCES-CEREVISIAE - CHARACTERIZATION OF MUTANTS IN 34 COMPLEMENTATION GROUPS 1986
EFFECT OF REPLACING URIDINE-33 IN YEAST TRANSFER RNAPHE ON THE REACTION WITH RIBOSOMES 1986
Effect of replacing uridine 33 in yeast tRNAPhe on the reaction with ribosomes. 1986
THE NUCLEAR-CODED SUBUNITS OF YEAST CYTOCHROME-C-OXIDASE - THE AMINO-ACID-SEQUENCES OF SUBUNITS-VII AND SUBUNITS-VIIA, STRUCTURAL SIMILARITIES BETWEEN THE 3 SMALLEST POLYPEPTIDES OF THE HOLOENZYME, AND IMPLICATIONS FOR BIOGENESIS 1986
The beta subunit of the Escherichia coli DNA polymerase III holoenzyme interacts functionally with the catalytic core in the absence of other subunits. 1986
BACTERIOPHAGE-T4 REGA PROTEIN - PURIFICATION OF A TRANSLATIONAL REPRESSOR 1985
Monoclonal antibodies specific for the alpha subunit of the Escherichia coli DNA polymerase III holoenzyme. 1984
Adenosine 5'-O-(3-thiotriphosphate) can support the formation of an initiation complex between the DNA polymerase III holoenzyme and primed DNA. 1984
Failure of translational repression in the phage f2 op3 mutant is not due to an altered coat protein-RNA interaction. 1984
ISOLATION AND SEQUENCE OF THE STRUCTURAL GENE FOR CYTOCHROME-C OXIDASE SUBUNIT-VI FROM SACCHAROMYCES-CEREVISIAE 1984
MITOCHONDRIAL GENE-EXPRESSION IN SACCHAROMYCES CEREVISIAE .1. OPTIMAL CONDITIONS FOR PROTEIN-SYNTHESIS IN ISOLATED-MITOCHONDRIA 1984
MITOCHONDRIAL GENE-EXPRESSION IN SACCHAROMYCES-CEREVISIAE .2. FIDELITY OF TRANSLATION IN ISOLATED-MITOCHONDRIA FROM WILD-TYPE AND RESPIRATORY-DEFICIENT MUTANT-CELLS 1984
QUANTITATION OF ENERGY COUPLING BETWEEN CA-2+, CALMODULIN, SKELETAL-MUSCLE MYOSIN LIGHT CHAIN KINASE, AND KINASE SUBSTRATES 1984
THE NUCLEAR-CODED SUBUNITS OF YEAST CYTOCHROME-C OXIDASE .1. FRACTIONATION OF THE HOLOENZYME INTO CHEMICALLY PURE POLYPEPTIDES AND THE IDENTIFICATION OF 2 NEW SUBUNITS USING SOLVENT-EXTRACTION AND REVERSED PHASE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY 1984
THE NUCLEAR-CODED SUBUNITS OF YEAST CYTOCHROME-C OXIDASE .2. THE AMINO-ACID-SEQUENCE OF SUBUNIT-VIII AND A MODEL FOR ITS DISPOSITION IN THE INNER MITOCHONDRIAL-MEMBRANE 1984
THE NUCLEAR-CODED SUBUNITS OF YEAST CYTOCHROME-C OXIDASE .3. IDENTIFICATION OF HOMOLOGOUS SUBUNITS IN YEAST, BOVINE HEART, AND NEUROSPORA-CRASSA CYTOCHROME-C OXIDASES 1984
Excess beta subunit can bypass the ATP requirement for highly processive synthesis by the Escherichia coli DNA polymerase III holoenzyme. 1983
NUCLEAR GENES FOR MITOCHONDRIAL PROTEINS - IDENTIFICATION AND ISOLATION OF A STRUCTURAL GENE FOR SUBUNIT-V OF YEAST CYTOCHROME-C OXIDASE 1983
POINT MUTATIONS OF THE ADENOVIRUS MAJOR LATE PROMOTER WITH DIFFERENT TRANSCRIPTIONAL EFFICIENCIES INVITRO 1983
The beta subunit of the DNA polymerase III holoenzyme becomes inaccessible to antibody after formation of an initiation complex with primed DNA. 1982
Independent locations of kinase and 3'-phosphatase activities on T4 polynucleotide kinase. 1982
Isolation and characterization of two mutant forms of T4 polynucleotide kinase. 1982
Size classes of products synthesized processively by two subassemblies of Escherichia coli DNA polymerase III holoenzyme. 1982
Purification and characterization of DNA polymerase III'. Identification of tau as a subunit of the DNA polymerase III holoenzyme. 1982
A CALORIMETRIC INVESTIGATION OF THE INTERACTION OF THE LAC REPRESSOR WITH INDUCER 1982
Size classes of products synthesized processively by DNA polymerase III and DNA polymerase III holoenzyme of Escherichia coli. 1981
HELA RIBOSOMAL PROTEIN-S6 - INSULIN AND DIBUTYRYL-CYCLIC-AMP AFFECT DIFFERENT PHOSPHOPEPTIDES 1981
Purification and characterization of the beta subunit of the DNA polymerase III holoenzyme of Escherichia coli. 1980
INHIBITION OF ADENYLATE-CYCLASE BY THE 2',3'-DIALDEHYDE OF ADENOSINE-TRIPHOSPHATE 1980
DNA polymerase III of Escherichia coli. Purification and identification of subunits. 1979
EXCHANGE AND STABILITY OF HELA RIBOSOMAL-PROTEINS INVIVO 1976
NON-HISTONE CHROMOSOMAL-PROTEINS FROM HELA-CELLS - SURVEY BY HIGH-RESOLUTION, 2-DIMENSIONAL ELECTROPHORESIS 1976
PROTEINS OF FRIEND LEUKEMIA-CELLS - COMPARISON OF HEMOGLOBIN-SYNTHESIZING AND NON-INDUCED POPULATIONS 1976
REGULATION OF GENE-32 EXPRESSION DURING BACTERIOPHAGE-T4 INFECTION OF ESCHERICHIA-COLI 1976
RELATIVE STOICHIOMETRY OF RIBOSOMAL-PROTEINS IN HELA-CELL NUCLEOLI 1976
TRANSLATIONAL, AUTOGENOUS REGULATION OF GENE-32 EXPRESSION DURING BACTERIOPHAGE-T4 INFECTION 1976
Total Synthesis of the Structural Gene for the Precursor of a Tyrosine Suppressor Transfer RNA from Escherichia coli 1. General Introduction 1976
Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 10. Enzymatic joining of chemically synthesized segments to form the DNA duplex corresponding to the nucleotide sequence 86-126 1976
Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 11. Enzymatic joining to form the total DNA duplex 1976
Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 3. Synthesis of deoxyribopolynucleotide segments corresponding to the nucleotide sequence 27-51 1976
Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 4. Synthesis of deoxyribopolynucleotide segments corresponding to the nucleotide sequence 47-78 1976
Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 5. Synthesis of the deoxyribopolynucleotide segments representing the nucleotide sequence 71-103 1976
Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 6. Synthesis of the deoxyribopolynucleotide segments corresponding to the nucleotide sequence 100-126 1976
EVIDENCE FOR HETEROGENEITY OF RIBOSOMES WITHIN HELA-CELL 1975
CALCULATED EQUILIBRIA OF PHOSPHOCREATINE AND ADENOSINE PHOSPHATES DURING UTILIZATION OF HIGH-ENERGY PHOSPHATE BY MUSCLE 1974
Assembly Checkpoint of the Proteasome is Mediated by Coordinated Actions of Proteasomal ATPase Chaperones 2023
Mediator kinase inhibition suppresses chronic inflammation in Down syndrome 2023

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